Panalto-DSR Capsule

Panalto-Dsr Capsule contains Pantoprazole (as enteric-coated pellets) 40 mg + Domperidone (as sustained/modified release) 30 mg. Prescription required.

Gastroesophageal reflux disease (GERD), acidity/heartburn, indigestion (dyspepsia), nausea and vomiting associated with acid reflux

Pantoprazole is a proton pump inhibitor that reduces stomach acid by blocking the gastric H+/K+ ATPase pump. Domperidone is a peripheral dopamine (D2) receptor antagonist that increases gastric motility and helps relieve nausea/vomiting, improving reflux symptoms.

Take 1 capsule as prescribed, usually once daily 30 minutes before food (preferably before breakfast). Swallow whole; do not crush or chew (contains enteric-coated/SR components).

Headache, diarrhea, abdominal pain, nausea, dry mouth, dizziness, flatulence, constipation

Use with caution in liver disease. Domperidone may increase risk of QT prolongation/serious heart rhythm problems—avoid in patients with known QT prolongation, significant cardiac disease, electrolyte disturbances, or when used with QT-prolonging medicines. Seek medical help for black stools, blood in vomit, persistent vomiting, unexplained weight loss, or severe abdominal pain. Long-term PPI use may be associated with low magnesium/vitamin B12, bone fracture risk, and gastrointestinal infections; use the lowest effective dose.

Ketoconazole/itraconazole/posaconazole/erlotinib (reduced absorption with pantoprazole), warfarin (monitor INR), digoxin (risk of hypomagnesemia-related toxicity), methotrexate high dose (increased levels), clopidogrel (possible reduced activation; consider alternative PPI if needed), strong CYP3A4 inhibitors like clarithromycin/erythromycin/ketoconazole/ritonavir (increase domperidone levels and QT risk), other QT-prolonging drugs (e.g., amiodarone, sotalol, quinolones, macrolides, antipsychotics)

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack. Keep out of reach of children.

Pantocid DSR Capsule, Pan DSR Capsule, Pentasure DSR Capsule, Pantop DSR Capsule, Pantosec DSR Capsule