Targocid 200 mg

Targocid 200 mg contains Teicoplanin 200 mg (as lyophilized powder) for injection and is used for serious. Prescription required.

Treatment of serious Gram-positive bacterial infections such as complicated skin and soft tissue infections, bone and joint infections (including osteomyelitis), hospital-acquired pneumonia caused by susceptible organisms, bacteraemia/septicaemia, and infective endocarditis; used especially when MRSA/MRSE is suspected or when patients cannot receive beta-lactams.

Teicoplanin is a glycopeptide antibiotic that inhibits bacterial cell wall synthesis by binding to D-Ala-D-Ala termini of peptidoglycan precursors. This prevents cross-linking of the cell wall, leading to bacterial death against susceptible Gram-positive organisms.

For IV or IM use only; reconstitute the vial with the recommended diluent and further dilute for IV infusion as per label/hospital protocol. Dose and duration are decided by the physician based on infection type, severity, kidney function and body weight; loading doses are commonly used initially. Administer at the same time each day; do not self-administer.

Injection site pain/phlebitis, rash, itching, fever, nausea, vomiting, diarrhoea, headache, dizziness, elevated liver enzymes, eosinophilia, thrombocytopenia

Prescription-only hospital antibiotic. Use only for confirmed/suspected susceptible Gram-positive infections; not active against most Gram-negative bacteria. Dose adjustment and monitoring required in renal impairment; monitor kidney function and blood counts during prolonged therapy. Rare but serious hypersensitivity reactions (including anaphylaxis, SJS/TEN) may occur—stop and seek urgent care if severe rash, facial swelling or breathing difficulty develops. Ototoxicity is rare but risk increases with concomitant ototoxic drugs; monitor hearing in high-risk patients. Caution in patients with known glycopeptide allergy (e.g., vancomycin).

Increased risk of nephrotoxicity/ototoxicity with aminoglycosides (amikacin/gentamicin), vancomycin, amphotericin B, colistin, cisplatin, and loop diuretics (furosemide). Additive nephrotoxicity with cyclosporine/tacrolimus and other nephrotoxic drugs.

Store unopened vial at or below 25°C, protected from light and moisture. After reconstitution/dilution, use immediately or store as per product label and institutional aseptic guidelines; do not freeze unless label permits.

Targocid 200 Injection (Sanofi), Teicoplanin 200 mg Injection (generic), Teicoplanin 200 Injection (various brands), Vancomycin 500/1 g Injection (alternative glycopeptide), Linezolid 600 mg (alternative for susceptible Gram-positive infections)