Tebina 500MG Tab

Tablet

Treatment of fungal infections of skin and nails such as onychomycosis (fungal nail infection), tinea corporis (ringworm), tinea cruris (jock itch), tinea pedis (athlete’s foot), and other dermatophyte infections as prescribed.

Terbinafine is an allylamine antifungal that inhibits squalene epoxidase, blocking ergosterol synthesis in fungal cell membranes. This leads to toxic accumulation of squalene and results in fungal cell death, especially against dermatophytes.

Tablet is taken by mouth exactly as prescribed. Can be taken with or without food; take at the same time each day. Duration depends on site and severity (skin infections usually weeks; nail infections often longer). Do not stop early without medical advice.

Nausea, abdominal pain, diarrhoea, headache, rash, itching, taste disturbance, loss of appetite, indigestion, dizziness, fatigue, elevated liver enzymes

Prescription-only antifungal. Terbinafine can rarely cause serious liver injury—avoid/use with caution in liver disease; baseline and periodic liver function tests may be advised, and stop/seek care if jaundice, dark urine, persistent nausea/vomiting, right upper abdominal pain, unusual tiredness or itching occurs. Use caution in renal impairment. Rare severe skin reactions (SJS/TEN) and blood disorders have been reported—seek urgent care for widespread rash, fever, sore throat, easy bruising/bleeding. May worsen psoriasis or lupus in susceptible patients. Not for self-medication for prolonged use.

CYP2D6 interactions: may increase levels/effects of tricyclic antidepressants, SSRIs (e.g., paroxetine/fluoxetine), antipsychotics, beta-blockers (e.g., metoprolol), and antiarrhythmics (e.g., propafenone/flecainide). Rifampicin may reduce terbinafine levels; cimetidine may increase levels. Warfarin—INR changes reported; monitor. Caffeine clearance may be reduced. Avoid other hepatotoxic drugs where possible.

Store below 25°C, protected from light and moisture. Keep in original blister pack and out of reach of children.

Terbinafine 500 mg Tablet (generic), Terbinafine 250 mg tablets (various brands), Lamisil Tablet (terbinafine), Terbicip Tablet (terbinafine), Terbinaforce Tablet (terbinafine)