Ursocol 300 Tablet

Drug | Tablet

Dissolution of cholesterol gallstones (when surgery is not suitable), primary biliary cholangitis (PBC) / cholestatic liver disease, symptomatic relief in cholestasis-related pruritus (as prescribed)

Ursodeoxycholic acid is a hydrophilic bile acid that reduces cholesterol saturation of bile by decreasing hepatic cholesterol secretion and increasing bile flow. It also protects liver cells and bile ducts from toxic bile acids, improving cholestasis and liver enzyme levels in certain cholestatic disorders.

Take the tablet whole with water, preferably with food or after meals to reduce stomach upset. Dose and duration depend on indication and body weight; use exactly as prescribed and continue regularly for best effect.

Diarrhoea, nausea, abdominal pain, indigestion, constipation, vomiting, headache, dizziness, rash, itching, increased liver enzymes

Use under medical supervision. Not recommended in patients with non-functioning gallbladder, calcified gallstones, frequent biliary colic, or obstruction of the biliary tract (e.g., complete biliary obstruction). Monitor liver function tests periodically, especially in PBC/cholestasis. Use with caution in severe liver disease, pancreatitis, or inflammatory bowel disease; stop and consult doctor if severe diarrhoea, worsening jaundice, or abdominal pain occurs.

Bile acid sequestrants (cholestyramine, colestipol) and antacids containing aluminium hydroxide may reduce absorption (separate dosing by 2–4 hours). Oestrogens, oral contraceptives and lipid-lowering drugs like clofibrate may increase biliary cholesterol and reduce gallstone dissolution efficacy. Cyclosporine levels may change; monitoring may be needed.

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

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