Distributor inventory | Tablet

Treatment of erectile dysfunction (impotence) in adult men; helps achieve and maintain an erection during sexual stimulation.

Sildenafil is a phosphodiesterase-5 (PDE5) inhibitor. It increases cGMP levels in the corpus cavernosum, enhancing nitric oxide–mediated blood flow to the penis during sexual stimulation. It does not cause an erection without sexual arousal.

Oral tablet. Usually taken as needed about 30–60 minutes before sexual activity (can be taken 30 minutes to 4 hours before). Swallow with water; may be taken with or without food, but high-fat meals may delay onset. Do not take more than once in 24 hours; dose as prescribed by a doctor.

Headache, flushing, dizziness, nasal congestion, indigestion, nausea, visual disturbance (blurred vision/blue tinge), back pain, muscle pain

Prescription-only medicine. Do not use with nitrates (e.g., nitroglycerin, isosorbide) or riociguat due to dangerous fall in blood pressure. Use with caution in heart disease, recent heart attack/stroke, uncontrolled hypertension/hypotension, severe liver impairment, severe kidney disease, bleeding disorders, peptic ulcer, anatomical deformation of penis, predisposition to priapism (e.g., sickle cell, leukemia, myeloma). Seek urgent help for chest pain, erection lasting >4 hours (priapism), sudden loss of vision or hearing. May cause dizziness—avoid driving if affected.

Nitrates and nitric oxide donors, riociguat, alpha-blockers (e.g., tamsulosin, doxazosin), strong CYP3A4 inhibitors (ketoconazole, itraconazole, ritonavir, cobicistat, clarithromycin), CYP3A4 inducers (rifampicin, carbamazepine, phenytoin), other PDE5 inhibitors, antihypertensives (additive BP lowering), grapefruit juice (may increase levels)

Store at room temperature (below 25°C), protected from moisture and light. Keep in original pack and out of reach of children.

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