Type 2 diabetes mellitus (as an add-on to diet and exercise) to improve glycaemic control in adults when dual therapy is appropriate.
How It Works
Sitagliptin is a DPP-4 inhibitor that increases incretin hormones, thereby increasing insulin release and decreasing glucagon levels in a glucose-dependent manner. Dapagliflozin is an SGLT2 inhibitor that lowers blood glucose by increasing urinary glucose excretion through the kidneys.
Directions for Use
Tablet for oral use. Take as prescribed by the doctor, usually once daily; may be taken with or without food, preferably at the same time each day. Maintain adequate hydration; follow diet/exercise advice and monitor blood glucose.
Not for type 1 diabetes or diabetic ketoacidosis. Risk of dehydration and low blood pressure (more in elderly/diuretics); maintain fluids. SGLT2 inhibitors may increase risk of genital mycotic infections, UTIs and rare Fournier’s gangrene—seek care for genital pain/swelling/fever. Rare risk of pancreatitis with sitagliptin—stop and consult if severe abdominal pain occurs. Monitor kidney function before and during therapy; use with caution/avoid in significant renal impairment as advised by physician. Use caution if history of recurrent UTIs, ketoacidosis, alcoholism, low-carb intake, or surgery/acute illness (ketoacidosis risk).
Drug Interactions
Insulin and sulfonylureas (increased hypoglycaemia risk),diuretics (increased dehydration/hypotension risk),rifampicin and other strong enzyme inducers (may reduce sitagliptin effect),digoxin (sitagliptin may increase levels),other glucose-lowering drugs (additive effect)
Storage Instructions
Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.
Substitutes
Istamet D 50/5 Tablet,Kombiglyze XR 5/500 Tablet,Qtern 5/5 Tablet (dapagliflozin+saxagliptin),Glyxambi 10/5 Tablet (empagliflozin+linagliptin),Jardiance Duo 25/5 Tablet (empagliflozin+linagliptin)
Frequently Asked Questions
What is this medicine used for?
Type 2 diabetes mellitus (as an add-on to diet and exercise) to improve glycaemic control in adults when dual therapy is appropriate.
Sitagliptin is a DPP-4 inhibitor that increases incretin hormones, thereby increasing insulin release and decreasing glucagon levels in a glucose-dependent manner. Dapagliflozin is an SGLT2 inhibitor that lowers blood glucose by increasing urinary glucose excretion through the kidneys.
How should I use this medicine?
Tablet for oral use. Take as prescribed by the doctor, usually once daily; may be taken with or without food, preferably at the same time each day. Maintain adequate hydration; follow diet/exercise advice and monitor blood glucose.
How should I store this medicine?
Store below 25°C in a cool, dry place. Protect from moisture and light. Keep out of reach of children.
Do I need a prescription for this product?
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
Can prices or availability change?
Yes. Prices and availability can change based on inventory and serviceability. The latest details are shown at checkout.
How do I place an order?
Select a variant, add to cart, enter delivery address, upload prescription if required, and pay securely.
Manufacturer & Brand
Brand:Zuventus Healthcare Ltd
Manufacturer:ZUVENTUS HEALTHCARE LTD`
HSN Code:30049099
Alternatives
Alternatives are suggested by pharmacists after reviewing your order and prescription.
Disclaimer: Product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalized guidance.
Sources: Manufacturer labeling/pack insert,CDSCO/drug safety communications,standard pharmacology texts,established medical literature on DPP-4 and SGLT2 inhibitors