Distributor inventory | Tablet

Prevention and treatment of nausea and vomiting due to chemotherapy, radiotherapy, and after surgery (post-operative nausea and vomiting).

Ondansetron is a selective 5-HT3 (serotonin) receptor antagonist. It blocks serotonin action in the gut and in the brain’s vomiting centre, thereby reducing nausea and vomiting.

Place the mouth-dissolving tablet on the tongue and allow it to dissolve; swallow with saliva (water not necessary). Use as prescribed by the doctor; may be taken with or without food. Do not chew or crush; handle with dry hands.

Headache, constipation, diarrhea, dizziness, fatigue, flushing

Use with caution in patients with heart rhythm problems (QT prolongation), electrolyte imbalance (low potassium/magnesium), severe liver disease (dose adjustment may be needed), and intestinal obstruction. Seek urgent care for palpitations, fainting, severe dizziness, or signs of allergy. Not recommended with apomorphine. May cause drowsiness in some people—avoid driving if affected.

Apomorphine (contraindicated), other QT-prolonging medicines (e.g., amiodarone, sotalol, macrolides, fluoroquinolones, antipsychotics), serotonergic drugs (SSRIs/SNRIs, tramadol, linezolid—risk of serotonin syndrome), CYP3A4 inducers (rifampicin, phenytoin, carbamazepine may reduce effect)

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack until use.

Emeset MD 8, Vomikind MD 8, Ondem MD 8, Ondansetron MD 8 (generic), Setron MD 8