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Treatment of hypertension (high blood pressure), angina (chest pain), and as add-on therapy in stable chronic heart failure; also used for rate control in certain tachyarrhythmias as prescribed.

Metoprolol is a cardioselective beta-1 adrenergic blocker. It reduces heart rate and the force of contraction, lowering blood pressure and myocardial oxygen demand. In heart failure, it helps improve cardiac function over time by reducing harmful sympathetic stimulation.

Take by mouth exactly as prescribed, usually once daily for prolonged-release tablets. Swallow whole with water; do not crush or chew. Can be taken with or without food, but take at the same time each day for best effect.

tiredness, dizziness, slow heart rate (bradycardia), low blood pressure, cold hands/feet, headache, nausea

Do not stop suddenly (may worsen angina/trigger heart attack); taper under medical supervision. Use with caution in asthma/COPD (may cause bronchospasm), diabetes (may mask low-sugar symptoms), thyroid disorders, peripheral vascular disease, and in patients with bradycardia, heart block, or acute decompensated heart failure. Monitor blood pressure and pulse; seek help if fainting, very slow pulse, wheezing, or worsening breathlessness/swelling occurs.

Other antihypertensives (additive hypotension), verapamil/diltiazem/amiodarone/digoxin (bradycardia/heart block), clonidine (rebound hypertension if withdrawn improperly), insulin/oral antidiabetics (masked hypoglycaemia), NSAIDs (reduced BP effect), CYP2D6 inhibitors like fluoxetine/paroxetine/quinidine (increased metoprolol levels).

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Metoprolol Succinate ER 25 mg tablet, Metolar XR 25 Tablet, Met XL 25 Tablet, Prolomet XL 25 Tablet, Seloken XL 25 Tablet