Sitagliptin 100 mg + Metformin hydrochloride 1000 mg (sustained release/extended release – check pack label)
Tablet
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Tablet · 1000 mg · 10`S
Before you take it
Consult doctor
Avoid
Monograph
Tablet
Type 2 diabetes mellitus: used to improve blood glucose control along with diet and exercise when dual therapy with metformin and a DPP-4 inhibitor is appropriate.
Sitagliptin is a DPP-4 inhibitor that increases incretin hormones, leading to increased insulin release and reduced glucagon secretion in a glucose-dependent manner. Metformin decreases hepatic glucose production and improves peripheral insulin sensitivity, reducing blood glucose levels.
Oral tablet. Take as prescribed by doctor, usually once daily with the evening meal (for SR/ER) or with meals to reduce stomach upset. Swallow whole; do not crush/chew if sustained/extended release. Monitor blood sugar regularly.
Nausea,diarrhoea,abdominal pain,loss of appetite,headache,upper respiratory tract infection,nasopharyngitis,dizziness,metallic taste
Prescription-only antidiabetic. Risk of lactic acidosis with metformin (higher risk in kidney impairment, dehydration, severe infection, low oxygen states, heavy alcohol use); stop and seek urgent care for deep/rapid breathing, severe weakness, abdominal pain. Not recommended in severe renal impairment; dose adjustment/avoid based on eGFR. Hold metformin before/after iodinated contrast procedures and major surgery as advised. Sitagliptin may rarely cause pancreatitis or severe joint pain; stop and consult doctor if severe abdominal pain. Use caution in elderly; monitor kidney function and vitamin B12 with long-term use. Not for type 1 diabetes or diabetic ketoacidosis.
Alcohol (increases lactic acidosis risk),iodinated contrast media,carbonic anhydrase inhibitors (e.g., topiramate/acetazolamide),cimetidine,diuretics/ACE inhibitors/NSAIDs (may worsen renal function),insulin or sulfonylureas (increased hypoglycaemia risk),digoxin (may increase levels with sitagliptin)
Store below 25°C in a dry place, protected from moisture and light. Keep in original pack and out of reach of children.
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Good to know
Type 2 diabetes mellitus: used to improve blood glucose control along with diet and exercise when dual therapy with metformin and a DPP-4 inhibitor is appropriate.
Nausea,diarrhoea,abdominal pain,loss of appetite,headache,upper respiratory tract infection,nasopharyngitis,dizziness,metallic taste
Sitagliptin is a DPP-4 inhibitor that increases incretin hormones, leading to increased insulin release and reduced glucagon secretion in a glucose-dependent manner. Metformin decreases hepatic glucose production and improves peripheral insulin sensitivity, reducing blood glucose levels.
Oral tablet. Take as prescribed by doctor, usually once daily with the evening meal (for SR/ER) or with meals to reduce stomach upset. Swallow whole; do not crush/chew if sustained/extended release. Monitor blood sugar regularly.
Store below 25°C in a dry place, protected from moisture and light. Keep in original pack and out of reach of children.
Yes, this product requires a valid prescription (Rx). Upload it during checkout when prompted.
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Brand
GLENMARK PHARMACEUTICALS
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Manufacturer: GLENMARK PHARMACEUTICALS
Medical disclaimer: product information is for awareness only and does not replace medical advice. For Rx medicines, a valid prescription is required. Consult your doctor or pharmacist for personalised guidance. Sources: Manufacturer labeling,CDSCO/Indian regulatory product information,established medical literature (metformin and sitagliptin prescribing information),standard clinical guidelines for type 2 diabetes
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