Zoryl 0.5MG Tab

Tablet

Type 2 diabetes mellitus (adult) to help control blood sugar, usually along with diet and exercise; may be used alone or with other antidiabetic medicines.

Glimepiride is a sulfonylurea that stimulates the pancreas to release insulin. It also improves peripheral insulin sensitivity, thereby lowering blood glucose levels.

Oral tablet. Take exactly as prescribed, usually once daily with breakfast or the first main meal. Swallow with water; do not skip meals after taking it. Dose is individualized based on blood glucose and HbA1c; monitor sugars regularly.

Hypoglycaemia (low blood sugar), dizziness, headache, nausea, abdominal discomfort, diarrhoea, weight gain, skin rash

Risk of hypoglycaemia—more likely with missed meals, excessive exercise, alcohol intake, elderly patients, liver/kidney impairment, or when combined with other antidiabetics. Use with caution in hepatic or renal disease; dose adjustment/close monitoring may be required. Avoid driving/operating machinery if you experience symptoms of low blood sugar. Inform doctor if you have sulfonamide allergy, G6PD deficiency (risk of haemolysis), severe infection, trauma or surgery (may require insulin). Not for type 1 diabetes or diabetic ketoacidosis.

Other antidiabetics (insulin, metformin) may increase hypoglycaemia risk; beta-blockers may mask hypoglycaemia symptoms; ACE inhibitors can potentiate glucose-lowering effect; corticosteroids, thiazide/loop diuretics, oral contraceptives, thyroid hormones and sympathomimetics may raise glucose; azole antifungals (e.g., fluconazole), macrolides, chloramphenicol may increase effect; rifampicin, phenytoin, carbamazepine may reduce effect; warfarin interaction possible—monitor INR; alcohol increases hypoglycaemia risk.

Store below 25°C in a dry place. Protect from light and moisture. Keep out of reach of children.

Amaryl 0.5 Tablet, Glimy 0.5 Tablet, Glimiprex 0.5 Tablet, Glypride 0.5 Tablet, Glimestar 0.5 Tablet