Zyrova Ez 40 Tab

Tablet

Used to treat high cholesterol (hypercholesterolaemia/mixed dyslipidaemia) when diet and exercise alone are not enough; helps reduce LDL cholesterol and triglycerides and lower cardiovascular risk in appropriate patients.

Rosuvastatin is a statin that inhibits HMG‑CoA reductase, reducing cholesterol production in the liver and increasing LDL clearance. Ezetimibe blocks intestinal absorption of cholesterol by inhibiting the NPC1L1 transporter. Together they provide stronger LDL reduction than either alone.

Oral tablet. Take exactly as prescribed, usually once daily, at the same time each day, with or without food. Continue diet and lifestyle changes; do not stop without medical advice.

Headache, dizziness, nausea, abdominal pain, constipation, diarrhoea, muscle pain (myalgia), weakness, increased liver enzymes

Not recommended in pregnancy or breastfeeding. Use with caution in liver disease, heavy alcohol use, hypothyroidism, kidney impairment, older age, or history of muscle disorders; risk of myopathy/rhabdomyolysis—seek care for unexplained muscle pain/weakness especially with fever/dark urine. Monitor lipid profile and liver enzymes as advised.

Cyclosporine, gemfibrozil/other fibrates, niacin (high dose), protease inhibitors (e.g., ritonavir combinations), warfarin/other anticoagulants (monitor INR), antacids containing aluminium/magnesium (may reduce rosuvastatin levels), bile acid sequestrants (reduce ezetimibe absorption—separate dosing), colchicine

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Rosuvas EZ 40 Tablet, Rozavel EZ 40 Tablet, Rosulip EZ 40 Tablet, Roseday EZ 40 Tablet, Crestor EZ 40 Tablet