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Prescription requiredSerum Institute Of India LtdAnti-ulcer agent and Analgesic and anti-inflammatory

Acendol R Capsule

Rabeprazole (20mg) + Aceclofenac (200mg)

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Acendol R Capsule is used for acendol-R Capsule SR is used for pain relief. It relieves pain and inflammation in rheumatoid arthritis, ankylosing spondylitis and osteoarthritis. It also relieves tooth ache, lower back pain, ear and throat pain.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Rabeprazole (20mg) + Aceclofenac (200mg)
Available variants: capsule 20mg + 200mg 10`S
Best price: ₹105 (₹10.51 per capsule)
MRP: ₹111
Prescription: Required
Manufacturer: SERUM INTERNATIONAL LTD`

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Acendol R Capsule

Acendol R Capsule contains Rabeprazole (20mg) + Aceclofenac (200mg). It belongs to the Proton pump inhibitor and Non-steroidal anti-inflammatory drug class of medicines.

Uses of Acendol R Capsule

  • Acendol-R Capsule SR is used for pain relief. It relieves pain and inflammation in rheumatoid arthritis
  • ankylosing spondylitis and osteoarthritis. It also relieves tooth ache
  • lower back pain
  • ear and throat pain.

Key benefits

  • Powerful and reliable relief of acidity
  • Heals ulcers and reflux damage
  • Usually taken once a day
  • Relieves pain and the swelling that causes it
  • Effective in arthritis and injury

How Acendol R Capsule works

Acendol-R Capsule SR is a combination of two medicines: Aceclofenac and Rabeprazole, which relieves pain. Aceclofenac is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Rabeprazole is a proton-pump inhibitor which prevents damage to the stomach lining caused by Aceclofenac.

How to take Acendol R Capsule

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Acendol-R Capsule SR is to be taken empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause confusion, blurred vision, sweating and a fast heartbeat. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Acendol R Capsule

Most side effects of Acendol R are mild and settle as the body adjusts. Reported side effects include:

  • Headache
  • Loose motions
  • Nausea
  • Stomach pain
  • Flatulence
  • Indigestion
  • Heartburn
  • Dizziness
  • Swelling of the ankles and feet

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Acendol R Capsule

PregnancyConsult doctor
BreastfeedingNo information is available on the use of Acendol-R Capsule SR during lactation. Please consult your doctor.
AlcoholUse with caution
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyAcendol-R Capsule SR should be used with caution in patients with kidney disease. Dose adjustment of Acendol-R Capsule SR may be needed. Please consult your doctor.<br>Use of Acendol-R Capsule SR is not recommended in patients with severe kidney disease.
LiverAcendol-R Capsule SR should be used with caution in patients with liver disease. Dose adjustment of Acendol-R Capsule SR may be needed. Please consult your doctor.<br>Use of Acendol-R Capsule SR is not recommended in patients with severe liver disease. Regular monitoring of liver function tests is advisable while the patient is taking this medicine.
Habit formingNo

Warnings and precautions

Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.

Do not take Acendol R if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.

Interactions with other medicines

Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.

How to store Acendol R Capsule

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Expert advice for Acendol R Capsule

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Acendol-R Capsule SR reduces pain and inflammation in conditions like rheumatoid arthritis, ankylosing spondylitis, and osteoarthritis.</li> <li>It may also be used to relieve pain in tooth, lower back, ear and throat.</li> <li>Take it with food to avoid getting an upset stomach.</li> <li>Take it as per the dose and duration prescribed by your doctor. Long term use may lead to serious side effects.</li> <li>It may cause dizziness and sleepiness. Don't drive or do anything that requires mental focus until you know how Acendol-R Capsule SR affects you.</li> <li>Inform your doctor if you are pregnant, planning to conceive or breastfeeding.</li> <li><div>Your doctor may regularly monitor your kidney function, liver function and levels of blood components if you are taking this medicine for long duration.</div></li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
SERUM INTERNATIONAL LTD`
Therapeutic class:
Anti-ulcer agent and Analgesic and anti-inflammatory
Drug class:
Proton pump inhibitor and Non-steroidal anti-inflammatory drug

Substitutes for Acendol R Capsule

Medicines with the same active ingredient (Rabeprazole (20mg) + Aceclofenac (200mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Acendol R Capsule
Acelong TabletSKN ORGANICS (P) LTD.`tablet · 10`S₹4557% cheaper
Cyra Ace TabletSYSTOPIC LABtablet · 10`S₹5746% cheaper
Acelong R TabletSKN ORGANICS (P) LTD.`tablet · 10`S₹8519% cheaper
Ashycloflam Rb Capsule1₹1032% cheaper
Dizaflam Ar CapsuleLA VINCITA LIFE SCIENCES PVT Lcapsule · 10`S₹1137% more
Aceflip R Capsule1X10₹11812% more
Raceclo CapsuleARISTO PHARMACEUTICALS PVT LTDcapsule · 10`S₹13630% more
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Acendol R Capsule FAQs

What is Acendol R Capsule used for?
Acendol R Capsule is commonly used for Acendol-R Capsule SR is used for pain relief. It relieves pain and inflammation in rheumatoid arthritis, ankylosing spondylitis and osteoarthritis. It also relieves tooth ache, lower back pain, ear and throat pain. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Acendol R Capsule?
Acendol R Capsule contains Rabeprazole (20mg) + Aceclofenac (200mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Acendol R Capsule?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Acendol R Capsule work?
Acendol-R Capsule SR is a combination of two medicines: Aceclofenac and Rabeprazole, which relieves pain.
Is Acendol R Capsule a prescription medicine?
Yes. Acendol R Capsule is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Acendol R Capsule?
The side effects reported most often with Acendol R are Headache, Loose motions, Nausea, Stomach pain, Flatulence. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Acendol R Capsule be taken during pregnancy?
Consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Acendol R.
Can I drink alcohol while taking Acendol R Capsule?
Use with caution
What if I miss a dose of Acendol R Capsule?
Take it as soon as you remember.
Is Acendol R Capsule habit forming?
No. Acendol R Capsule is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Acendol R Capsule?
Acelong Tablet has the same active ingredient and strength and is listed from ₹45 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Acendol R Capsule cost on PingMeDoc Pharmacy?
Acendol R Capsule starts at ₹105 (MRP ₹111) on PingMeDoc Pharmacy. Available in capsule 20mg + 200mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Acendol R Capsule?
Acendol R Capsule is manufactured by SERUM INTERNATIONAL LTD`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Acendol R Capsule delivered?
Acendol R Capsule is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Acendol R Capsule, Quick facts

Salt
Rabeprazole (20mg) + Aceclofenac (200mg)
Form
capsule
Best price
₹105 (₹10.51 per capsule)
MRP
₹111
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Serum Institute Of India Ltd
Manufacturer
SERUM INTERNATIONAL LTD`
Therapeutic class
Anti-ulcer agent and Analgesic and anti-inflammatory
Drug class
Proton pump inhibitor and Non-steroidal anti-inflammatory drug
Habit forming
No
Variants
capsule 20mg + 200mg 10`S
Delivery
Standard across India

References

The information on Acendol R Capsule is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack information
  2. Indian drug brand databases, established medical literature
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Acendol R Capsule.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.