
8X Cream
Cipla Limited - Cream - 30 G
Prescription required
Amantadine (129mg)
Amantrel ER 129 mg Tablet is used for this medicine is used in the treatment of alzheimer's disease, dementia and parkinson's disease.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Amantrel ER 129 mg Tablet contains Amantadine (129mg). It belongs to the Anti-dementia / anti-parkinsonian agent class of medicines.
Amantadine supports the chemical messengers in the brain that control memory, attention and movement.
Swallow the tablet whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it at exactly the times prescribed. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause severe confusion, abnormal movements, a very slow pulse and collapse. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Amantrel ER are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult your doctor before using this in pregnancy. |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Do not drink alcohol while taking this medicine. |
| Driving | Do not drive or operate machinery while taking this medicine. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Never stop a Parkinson's medicine suddenly — this can cause a severe and dangerous deterioration. Dose timing matters a great deal in Parkinson's disease. Take it at exactly the times prescribed. Report sudden daytime sleep attacks, hallucinations, or new gambling, spending or other impulsive behaviour — these are recognised effects and the dose may need review. Rise slowly from sitting or lying; a drop in blood pressure on standing is common.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Your doctor will assess suitability if you have heart, eye or psychiatric conditions.
Anti-emetics such as metoclopramide and some antipsychotics can worsen Parkinson's symptoms. High-protein meals can reduce the absorption of levodopa — ask your doctor about timing.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Keep a fixed dosing schedule, with alarms if needed. Involve a family member in the routine, and take a symptom diary to appointments.

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The information on Amantrel ER 129 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.