Amicin 250 mg Injection Vial

Composition of Amicin 250 mg Injection Vial

Amicin 250 mg Injection Vial contains Amikacin 250 mg (as amikacin sulfate) injection (vial). It belongs to the Aminoglycoside antibiotic class of medicines.

Uses of Amicin 250 mg Injection Vial

• Treatment of serious bacterial infections caused by susceptible organisms
• including complicated urinary tract infections
• respiratory tract infections
• intra-abdominal infections
• skin and soft tissue infections
• bone and joint infections
• septicemia
• and infections in hospitalized patients (often in combination with other antibiotics).

Key benefits

• Broad activity against Gram-negative bacteria
• Useful in severe hospital-acquired infections
• Bactericidal action
• Option for infections resistant to some other antibiotics
• Can be used in combination therapy for serious infections

How Amicin 250 mg Injection Vial works

Amikacin is an aminoglycoside antibiotic that binds to the 30S ribosomal subunit of bacteria. It inhibits protein synthesis and causes production of faulty proteins, leading to bacterial cell death (bactericidal).

How to take Amicin 250 mg Injection Vial

For intravenous infusion or intramuscular injection only; to be administered by a healthcare professional. Dose and duration depend on infection severity, age, weight, kidney function and culture sensitivity; maintain adequate hydration and complete the prescribed course.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Amicin 250 mg Injection Vial

Most side effects of Amicin are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• injection site pain
• headache
• dizziness
• rash
• fever
• increased blood urea/creatinine
• decreased urine output
• hearing changes (tinnitus/hearing loss)
• vertigo

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Amicin 250 mg Injection Vial

Warnings and precautions

Prescription-only injectable antibiotic. Risk of nephrotoxicity and ototoxicity—monitor kidney function and hearing, especially with prolonged therapy, high doses, dehydration, elderly, or pre-existing renal impairment. Can cause neuromuscular blockade/respiratory depression (higher risk in myasthenia gravis, Parkinsonism, or with anesthetics/neuromuscular blockers). Adjust dose in renal impairment; therapeutic drug monitoring may be required. Use only for proven/suspected susceptible bacterial infections; not effective for viral infections.

Do not take Amicin if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Other nephrotoxic/ototoxic drugs (e.g., vancomycin, amphotericin B, cisplatin, cyclosporine, tacrolimus), loop diuretics (furosemide, ethacrynic acid), other aminoglycosides, neuromuscular blocking agents/anesthetics (increased risk of respiratory depression), NSAIDs (may increase aminoglycoside levels), penicillins/cephalosporins (compatibility issues if mixed; administer separately).

How to store Amicin 250 mg Injection Vial

Store below 25°C, protect from light, do not freeze. Keep vial in original carton; use reconstituted/diluted solution as per label/institutional policy and discard unused portion.

Expert advice for Amicin 250 mg Injection Vial

Space the doses evenly and complete the course. Take tetracyclines with a full glass of water and stay upright for half an hour afterwards. Never use a leftover antibiotic, or someone else's, for a new illness.

Manufacturer and class

Manufacturer:

ZYDUS HEALTHCARE PHARMA

Therapeutic class:

Antibiotic

Drug class:

Aminoglycoside antibiotic