Amicin 500 mg Injection Vial

Composition of Amicin 500 mg Injection Vial

Amicin 500 mg Injection Vial contains Amikacin 500 mg (as Amikacin sulfate) injection. It belongs to the Aminoglycoside antibiotic class of medicines.

Uses of Amicin 500 mg Injection Vial

• Treatment of severe bacterial infections caused by susceptible organisms such as septicemia
• hospital-acquired/ventilator-associated pneumonia
• complicated urinary tract infections
• intra-abdominal infections
• skin/soft tissue infections
• bone and joint infections; also used with other drugs for drug-resistant tuberculosis as per specialist advice

Key benefits

• Treats severe gram-negative infections
• Useful in complicated urinary tract infections
• Effective in hospital-acquired pneumonia/sepsis
• Option for infections resistant to other antibiotics
• Used in MDR-TB regimens with specialist care

How Amicin 500 mg Injection Vial works

Amikacin is an aminoglycoside antibiotic that binds to the 30S bacterial ribosomal subunit. It inhibits protein synthesis and causes misreading of mRNA, leading to bacterial cell death (bactericidal).

How to take Amicin 500 mg Injection Vial

For intravenous or intramuscular use only, to be administered by a healthcare professional. Dose and duration depend on infection severity, body weight and kidney function; therapeutic drug monitoring may be needed. Maintain adequate hydration; do not self-inject.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Amicin 500 mg Injection Vial

Most side effects of Amicin are mild and settle as the body adjusts. Reported side effects include:

• Injection site pain
• nausea
• vomiting
• headache
• dizziness
• rash
• fever
• increased blood urea/creatinine (kidney impairment)
• hearing changes (tinnitus/hearing loss)
• vertigo
• neuromuscular weakness

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Amicin 500 mg Injection Vial

Warnings and precautions

Prescription-only antibiotic. Risk of nephrotoxicity and ototoxicity—higher with prolonged therapy, high doses, dehydration, elderly, and kidney disease; monitor renal function and hearing. May cause neuromuscular blockade/respiratory depression, especially in myasthenia gravis or with anesthetics. Use only for susceptible bacterial infections; not effective for viral infections. Dose adjustment required in renal impairment.

Do not take Amicin if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

Other nephrotoxic drugs (e.g., vancomycin, amphotericin B, cisplatin, cyclosporine/tacrolimus), loop diuretics (furosemide, ethacrynic acid) increase ototoxicity risk, other aminoglycosides, neuromuscular blockers and anesthetics (enhanced blockade), polymyxins, cephalosporins (additive kidney risk), NSAIDs may worsen renal function

How to store Amicin 500 mg Injection Vial

Store below 25°C, protected from light. Do not freeze. Keep in original pack; use immediately after opening/reconstitution as per label and discard unused portion.

Expert advice for Amicin 500 mg Injection Vial

Space the doses evenly and complete the course. Take tetracyclines with a full glass of water and stay upright for half an hour afterwards. Never use a leftover antibiotic, or someone else's, for a new illness.

Manufacturer and class

Manufacturer:

ZYDUS HEALTHCARE PHARMA

Therapeutic class:

Antibiotic

Drug class:

Aminoglycoside antibiotic