Aziderm Plus

Composition of Aziderm Plus

Aziderm Plus contains Azelaic Acid 20% w/w + Clindamycin 1% w/w (topical gel/cream). It belongs to the Dicarboxylic acid (azelaic acid) + Lincosamide antibiotic (clindamycin) class of medicines.

Uses of Aziderm Plus

• Treatment of acne (pimples) including inflammatory acne; helps reduce comedones
• redness and post-acne marks; may also help in mild rosacea-associated bumps as advised by doctor.

Key benefits

• Reduces acne-causing bacteria and inflammation
• Unclogs pores and reduces blackheads/whiteheads
• Helps fade post-acne marks and uneven tone
• Improves redness and bumps with regular use

How Aziderm Plus works

Azelaic acid reduces keratin build-up in pores (comedolytic), decreases acne-causing bacteria and inflammation, and helps fade hyperpigmentation. Clindamycin is a topical antibiotic that inhibits bacterial protein synthesis, reducing Cutibacterium acnes and inflammation.

How to take Aziderm Plus

For external use only. Clean and dry the affected area, then apply a thin layer once daily initially; may increase to twice daily if tolerated or as directed by a doctor. Avoid eyes, lips, inside nose and broken/irritated skin; wash hands after application. Use sunscreen in daytime and moisturiser if dryness occurs.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. It can cause vomiting, severe loose motions and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Aziderm Plus

Most side effects of Aziderm Plus are mild and settle as the body adjusts. Reported side effects include:

• Burning/stinging
• itching
• dryness
• peeling
• redness
• irritation
• rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Aziderm Plus

Warnings and precautions

For external use only. Do not use on broken skin or around eyes/mucosa. Stop and seek medical advice if severe irritation, swelling, or allergic reaction occurs. Prolonged/indiscriminate use of topical antibiotics can lead to resistance—use for the duration advised and avoid combining with other topical antibiotics unless prescribed. Rarely, topical clindamycin may cause antibiotic-associated diarrhoea/colitis; discontinue and consult a doctor if severe or persistent diarrhoea occurs. Use caution in patients with a history of colitis/IBD. Avoid excessive sun exposure; use sunscreen.

Do not take Aziderm Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.

Interactions with other medicines

Other topical irritants/peeling agents (retinoids, benzoyl peroxide, salicylic acid, alcohol-based products) may increase irritation; consider staggered use. Neuromuscular blocking agents may have enhanced effect with clindamycin (rare with topical).

How to store Aziderm Plus

Store below 25°C, protected from heat and direct light. Keep the tube tightly closed and out of reach of children. Do not freeze.

Expert advice for Aziderm Plus

Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars. Space the doses evenly and complete the course. Take tetracyclines with a full glass of water and stay upright for half an hour afterwards. Never use a leftover antibiotic, or someone else's, for a new illness.

Manufacturer and class

Manufacturer:

MICRO LABS

Therapeutic class:

Anti-acne (topical)

Drug class:

Dicarboxylic acid (azelaic acid) + Lincosamide antibiotic (clindamycin)