
Benadryl Cough Formula
Johnson & Johnson Pvt Ltd - 50 ml
Dextromethorphan Hydrobromide 10 mg/5 ml
Benadryl DR Cough Syrup is used for dry (non-productive) cough, throat irritation-related cough, cough due to common cold or allergy (symptomatic relief).
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Benadryl DR Cough Syrup contains Dextromethorphan Hydrobromide 10 mg/5 ml. It belongs to the Non-opioid antitussive class of medicines.
Dextromethorphan is a centrally acting antitussive. It suppresses the cough reflex by acting on the cough center in the brain, reducing the urge to cough.
Take by mouth using a measuring cup/spoon. Usually taken every 6–8 hours as needed; follow the label/doctor’s advice. Can be taken with or without food. Do not exceed the recommended dose; not for prolonged use without medical advice.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause vomiting, severe drowsiness, a racing heart and, with codeine, dangerously slow breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Benadryl DR Cough are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Consult doctor |
|---|---|
| Breastfeeding | Consult your doctor before using this while breastfeeding. |
| Alcohol | Avoid |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Use with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function. |
| Liver | Use with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function. |
| Habit forming | No |
Do not use in children below the age recommended on the label without medical advice. Avoid driving or operating machinery if drowsy. Do not use for cough with excessive mucus, chronic cough (asthma/COPD/smoking), or if fever/rash/persistent symptoms occur—seek medical advice. Risk of misuse/overdose; do not exceed dose. Use caution in liver disease. Seek urgent care for serotonin syndrome symptoms (agitation, confusion, sweating, fast heartbeat, tremor) especially if on serotonergic medicines.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Codeine-containing preparations are not for children, or for anyone with breathing difficulty.
MAO inhibitors (e.g., selegiline, linezolid) and within 14 days of stopping them, SSRIs/SNRIs/TCAs (risk of serotonin syndrome), other CNS depressants (alcohol, sedatives), serotonergic agents (tramadol, triptans), CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine) may increase effects
Store below 25°C in a cool, dry place. Protect from light. Keep the bottle tightly closed. Keep out of reach of children.
Drink plenty of water — it thins mucus better than any syrup. Steam inhalation helps congestion and costs nothing. Measure the dose with the cup supplied.

Johnson & Johnson Pvt Ltd - 50 ml

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The information on Benadryl DR Cough Syrup is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.