Biotretin 10 mg Capsule

Composition of Biotretin 10 mg Capsule

Biotretin 10 mg Capsule contains Isotretinoin 10 mg capsule. It belongs to the Retinoid (oral retinoid; isotretinoin) class of medicines.

Uses of Biotretin 10 mg Capsule

Treatment of severe acne (nodular/cystic acne) that is resistant to adequate courses of standard therapy including systemic antibiotics and topical treatments

Key benefits

• Reduces severe acne lesions
• Decreases sebum/oiliness
• Prevents new comedone formation
• Lowers acne-related inflammation
• Helps reduce risk of scarring when used appropriately

How Biotretin 10 mg Capsule works

Isotretinoin is an oral retinoid that reduces sebum (oil) production by shrinking sebaceous glands. It also normalizes skin cell shedding in follicles and has anti-inflammatory effects, thereby reducing comedones and acne lesions.

How to take Biotretin 10 mg Capsule

Take the capsule exactly as prescribed by a dermatologist, usually once or twice daily with food (preferably a fatty meal) and water; swallow whole without crushing or chewing. Use for the prescribed duration; regular follow-up and lab monitoring may be required.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Biotretin 10 mg Capsule

Most side effects of Biotretin are mild and settle as the body adjusts. Reported side effects include:

• Dry lips
• dry skin
• dry eyes
• nosebleeds
• skin peeling
• photosensitivity
• headache
• muscle/joint pain
• increased liver enzymes
• increased triglycerides
• mood changes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Biotretin 10 mg Capsule

Warnings and precautions

Highly teratogenic: must not be used in pregnancy; effective contraception required before, during and after therapy as advised; discontinue and seek urgent medical advice if pregnancy occurs. Avoid blood donation during treatment and for at least 1 month after stopping. Monitor liver function and lipids; use with caution in liver disease, hyperlipidemia, diabetes, depression or other psychiatric illness. Avoid excessive sun exposure; use sunscreen. Do not use with tetracyclines (risk of intracranial hypertension). Report severe headache/visual changes, severe abdominal pain, persistent diarrhea/bleeding, or significant mood changes.

Do not take Biotretin if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.

Interactions with other medicines

Tetracyclines (e.g., doxycycline, minocycline), vitamin A supplements/other retinoids, alcohol (increases risk of hypertriglyceridemia/hepatotoxicity), hepatotoxic medicines, corticosteroids (may increase risk of osteoporosis), phenytoin (bone effects)

How to store Biotretin 10 mg Capsule

Store below 25°C in a cool, dry place, protected from light and moisture. Keep in original packaging and out of reach of children.

Expert advice for Biotretin 10 mg Capsule

Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars.

Manufacturer and class

Manufacturer:

BIOSWIZZ PHARMACEUTICALS LTD

Therapeutic class:

Anti-acne

Drug class:

Retinoid (oral retinoid; isotretinoin)