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Prescription requiredGI PharmaANTI INFECTIVES

Cefosul 1.5 Injection

Cefoperazone (1000mg) + Sulbactam (500mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Izone-S Injection₹264View
  • Lactagard 1500 Injection₹338View
  • Zofactum 1.5 g Injection₹454View

Cefosul 1.5 Injection is used for treatment of Bacterial infections.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Cefoperazone (1000mg) + Sulbactam (500mg)
Available variants: injection 1000mg + 500mg VIAL
Best price: ₹220
MRP: ₹231
Prescription: Required
Manufacturer: GI PHARMA

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Cefosul 1.5 Injection

Cefosul 1.5 Injection contains Cefoperazone (1000mg) + Sulbactam (500mg). It belongs to the Cephalosporin and Penicillin class of medicines.

Uses of Cefosul 1.5 Injection

Treatment of Bacterial infections

Key benefits

  • In Treatment of Bacterial infections Cefosul 1000mg/500mg Injection contains two different medicines
  • Cefoperazone and Sulbactum
  • that work together to kill the bacteria that cause infections. Cefoperazone works by stopping the growth of bacteria. Sulbactam reduces resistance and enhances the activity of Cefoperazone against bacteria. Cefosul 1000mg/500mg Injection can be used to treat many different bacterial infections such as ear
  • sinus
  • throat
  • lung
  • urinary tract
  • skin and soft tissues. This medicine usually makes you feel better within a few days
  • but you should continue taking it as prescribed even when you feel better to make sure that all bacteria are killed and do not become resistant.

How Cefosul 1.5 Injection works

Cefosul 1000mg/500mg Injection is a combination of two medicines: Cefoperazone and Sulbactam. Cefoperazone is an antibiotic. It works by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Sulbactam is a beta-lactamase inhibitor which reduces resistance and enhances the activity of Cefoperazone against bacteria.

How to take Cefosul 1.5 Injection

Take exactly as prescribed by your doctor.

Side effects of Cefosul 1.5 Injection

Most side effects of Cefosul are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Cefosul 1.5 Injection

PregnancyPregnancy SAFE IF PRESCRIBED
BreastfeedingBreast feeding SAFE IF PRESCRIBED
AlcoholAlcohol UNSAFE
DrivingDriving CONSULT YOUR DOCTOR
KidneyKidney CONSULT YOUR DOCTOR
LiverLiver CONSULT YOUR DOCTOR
Habit formingNo

Warnings and precautions

Finish the whole course even after you feel better — stopping early breeds resistant bacteria. Tell your doctor if you have ever had a severe reaction to penicillin; a small proportion of people react to both groups. Report severe or watery loose motions during or after the course rather than treating them yourself. Several medicines in this group are on Schedule H1 precisely because overuse drives antibiotic resistance. Take it only when a doctor has prescribed it for you. Finish the whole course even after you feel better. Stopping early lets the strongest bacteria survive, and they are the ones that come back resistant. Stop and seek emergency care for swelling of the face or throat, difficulty breathing, or a widespread rash — a penicillin allergy can be serious. Tell every doctor and pharmacist if you have ever reacted to penicillin. Tell your doctor if loose motions become severe or watery, or continue after the course — this needs attention rather than an anti-diarrhoeal. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses.

Do not take Cefosul if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known allergy to cephalosporin antibiotics. Not for anyone with a known penicillin allergy.

Interactions with other medicines

Antacids, iron and zinc reduce absorption — separate them by a couple of hours. Tell your doctor if you take a blood thinner. May reduce the reliability of the oral contraceptive pill if you have vomiting or loose motions — use additional precautions during the course. Tell your doctor if you take methotrexate or a blood thinner.

How to store Cefosul 1.5 Injection

Store as printed on the carton — some injections need refrigeration and must not be frozen. Keep out of the reach of children.

Expert advice for Cefosul 1.5 Injection

You have been prescribed this combination medicine to treat bacterial infections even if they have developed resistance. Finish the prescribed course, even if you start to feel better. Stopping it early may make the infection come back and harder to treat. Diarrhea may occur as a side effect. Taking probiotics along with Cefosul 1000mg/500mg Injection may help. Talk to your doctor if you notice bloody stools or develop abdominal cramps. Stop taking Cefosul 1000mg/500mg Injection and inform your doctor immediately if you develop an itchy rash, swelling of the face, throat or tongue or breathing difficulties while taking it.

Manufacturer and class

Manufacturer:
GI PHARMA
Therapeutic class:
ANTI INFECTIVES
Drug class:
Cephalosporin and Penicillin

Substitutes for Cefosul 1.5 Injection

Medicines with the same active ingredient (Cefoperazone (1000mg) + Sulbactam (500mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Cefosul 1.5 Injection
Izone-S InjectionEYSYS PHARMAinjection · VIAL₹26420% more
Lactagard 1500 InjectionIPCA LABORATORIES LTD`injection · 1`S₹33854% more
Zofactum 1.5 g Injection1*20₹454107% more
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Cefosul 1.5 Injection FAQs

What is Cefosul 1.5 Injection used for?
Cefosul 1.5 Injection is commonly used for Treatment of Bacterial infections. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Cefosul 1.5 Injection?
Cefosul 1.5 Injection contains Cefoperazone (1000mg) + Sulbactam (500mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How does Cefosul 1.5 Injection work?
Cefosul 1000mg/500mg Injection is a combination of two medicines: Cefoperazone and Sulbactam.
Is Cefosul 1.5 Injection a prescription medicine?
Yes. Cefosul 1.5 Injection is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Cefosul 1.5 Injection?
The side effects reported most often with Cefosul are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Cefosul 1.5 Injection be taken during pregnancy?
Pregnancy SAFE IF PRESCRIBED Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Cefosul.
Can I drink alcohol while taking Cefosul 1.5 Injection?
Alcohol UNSAFE
Is Cefosul 1.5 Injection habit forming?
No. Cefosul 1.5 Injection is not known to be habit forming when taken as prescribed.
How much does Cefosul 1.5 Injection cost on PingMeDoc Pharmacy?
Cefosul 1.5 Injection starts at ₹220 (MRP ₹231) on PingMeDoc Pharmacy. Available in injection 1000mg + 500mg VIAL. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Cefosul 1.5 Injection?
Cefosul 1.5 Injection is manufactured by GI PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Cefosul 1.5 Injection delivered?
Cefosul 1.5 Injection is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Cefosul 1.5 Injection, Quick facts

Salt
Cefoperazone (1000mg) + Sulbactam (500mg)
Form
injection
Best price
₹220
MRP
₹231
Prescription
Required (Rx)
Schedule
Schedule H1
Brand
GI PHARMA
Manufacturer
GI PHARMA
Therapeutic class
ANTI INFECTIVES
Drug class
Cephalosporin and Penicillin
Habit forming
No
Variants
injection 1000mg + 500mg VIAL
Delivery
Standard across India

References

The information on Cefosul 1.5 Injection is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Cefosul 1.5 Injection.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.