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Prescription requiredIntas Pharmaceuticals LtdAnxiolytic and hypnotic and Antidepressant
Depran 5
CLONAZEPAM-0.5MG+ESCITALOPRAM-5MG
Available at our pharmacy counter
This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.
In-store reference price ₹184
Depran 5 is used for this medicine is used in the treatment of anxiety, insomnia, panic disorder, seizures, muscle spasm, depression, obsessive compulsive disorder, nerve pain and migraine prevention.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated October 2026
Licensed pharmacyPharmacist-verified order
Key details
Salt: CLONAZEPAM-0.5MG+ESCITALOPRAM-5MG
Available variants: NA 15`S
Best price: ₹184
MRP: ₹194
Prescription: Required
Manufacturer: INTAS PHARMACEUTICALS`
Ordering notes
This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Depran 5
Depran 5 contains CLONAZEPAM-0.5MG+ESCITALOPRAM-5MG. It belongs to the Benzodiazepine / sedative-hypnotic and Antidepressant class of medicines.
Uses of Depran 5
- Anxiety
- Insomnia
- Panic disorder
- Seizures
- Muscle spasm
- Depression
- Obsessive compulsive disorder
- Nerve pain
- Migraine prevention
Benefits of Depran 5
- In Anxiety
- Depran calms the nervous system quickly, easing acute anxiety, panic and the racing heart and tremor that go with it. It is intended for short-term use.
- In Insomnia
- Depran helps you fall asleep and stay asleep when sleep has broken down, so you can function the next day while the cause is dealt with.
- In Panic disorder
- Depran reduces the frequency and intensity of panic attacks, giving breathing space for longer-term treatment to work.
- In Seizures
- Depran stops a prolonged seizure or a cluster of seizures quickly, and is used in some forms of epilepsy to prevent them.
- In Muscle spasm
- Depran relaxes severe muscle spasm and the pain it causes, including spasm caused by nerve conditions.
- In Depression
- Depran restores the balance of the brain's chemical messengers, gradually lifting mood, energy, sleep and appetite. The benefit builds over several weeks, which is why it is important to keep taking it.
- In Obsessive compulsive disorder
- Depran reduces the intrusive thoughts and the urge to repeat rituals, usually alongside talking therapy.
- In Nerve pain
- Depran dampens the pain signals from damaged nerves, easing burning, shooting or tingling pain that ordinary painkillers do not touch.
- In Migraine prevention
- Depran, taken every day, reduces how often migraines come and how severe they are. It does not treat an attack once it has started.
How Depran 5 works
This medicine combines 2 active ingredients: Clonazepam and Escitalopram. Clonazepam calms over-activity in the brain, which relieves anxiety and helps sleep come more easily. Escitalopram restores the balance of the chemical messengers in the brain that regulate mood, sleep and the way pain is felt.
How to take Depran 5
Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause deep unconsciousness and dangerously slow breathing, particularly with alcohol or an opioid. It can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Depran 5
Most side effects of Depran are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Drowsiness
- Dizziness
- Unsteadiness
- Poor concentration
- Memory lapses
- Dry mouth
- Nausea
- Drowsiness or difficulty sleeping
- Headache
- Weight change
- Reduced sexual desire
- Constipation
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Depran 5
- AlcoholUNSAFE
- Do not drink alcohol while taking this medicine.
- PregnancyUNSAFE
- Not recommended in pregnancy. It may harm the developing baby, so tell your doctor at once if you are or might be pregnant.
- Breast feedingUNSAFE
- Not recommended while breastfeeding.
- DrivingUNSAFE
- Do not drive or operate machinery while taking this medicine.
- KidneyCAUTION
- Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
- LiverCONSULT YOUR DOCTOR
- Consult your doctor if you have liver disease.
- Habit formingYES
- This medicine can cause dependence with prolonged use. Take it only under medical supervision and do not stop it abruptly.
Warnings and precautions
These medicines cause dependence. They are intended for the shortest possible course — usually two to four weeks — and are not a long-term treatment for anxiety or sleeplessness. Never stop a regular course suddenly. Withdrawal can cause severe anxiety, tremor and fits. Your doctor will taper it slowly. Do not drive or operate machinery. Drowsiness and slowed reactions can continue into the next day. Never combine with alcohol or with opioid painkillers — together they can stop your breathing. Older people are far more likely to fall, become confused or have memory problems on these medicines. Several of these are Schedule H1 medicines and must be dispensed against a prescription and entered in the pharmacy register. These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.
Do not take Depran if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe breathing problems, sleep apnoea, or severe liver disease. Not for anyone with a history of dependence, except under specialist supervision. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Interactions with other medicines
Alcohol, opioids, antihistamines, muscle relaxants and other sedatives all deepen the sedation, sometimes fatally. Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.
How to store Depran 5
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Quick tips for Depran 5
- Use it for the shortest course, and ask your doctor about talking therapy and sleep routine, which work without dependence.
- Take it only at bedtime if it is for sleep, and allow a full night before driving.
- Never share these medicines, and keep them secured.
- Give it a fair trial of several weeks, and keep your review appointments.
- Take it at the same time each day.
- At night if it makes you drowsy, in the morning if it disturbs sleep.
- Talking therapy alongside medicine works better than either alone for most people.
Manufacturer and class
- Manufacturer:
- INTAS PHARMACEUTICALS`
- Therapeutic class:
- Anxiolytic and hypnotic and Antidepressant
- Drug class:
- Benzodiazepine / sedative-hypnotic and Antidepressant
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Depran 5 FAQs
What is Depran 5 used for?
Depran 5 is commonly used for anxiety, insomnia, panic disorder, seizures, muscle spasm, depression, obsessive compulsive disorder, nerve pain and migraine prevention. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Depran 5?
Anxiety: Depran calms the nervous system quickly, easing acute anxiety, panic and the racing heart and tremor that go with it. It is intended for short-term use. It is also used for insomnia, panic disorder, seizures.
What is the salt in Depran 5?
Depran 5 contains CLONAZEPAM-0.5MG+ESCITALOPRAM-5MG. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Depran 5?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Depran 5 work?
This medicine combines 2 active ingredients: Clonazepam and Escitalopram.
Is Depran 5 a prescription medicine?
Yes. Depran 5 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Depran 5?
The side effects reported most often with Depran are Drowsiness, Dizziness, Unsteadiness, Poor concentration, Memory lapses. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Depran 5 be taken during pregnancy?
Depran 5 is not recommended in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Depran.
Can I drink alcohol while taking Depran 5?
No. Do not drink alcohol while taking Depran 5.
What if I miss a dose of Depran 5?
Take it as soon as you remember.
Is Depran 5 habit forming?
Yes. Depran 5 can cause dependence with prolonged use. Take Depran only as directed and for the duration your doctor advises.
How much does Depran 5 cost on PingMeDoc Pharmacy?
Depran 5 starts at ₹184 (MRP ₹194) on PingMeDoc Pharmacy. Available in NA 15`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Depran 5?
Depran 5 is manufactured by INTAS PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Depran 5 delivered?
Depran 5 is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.
Depran 5, Quick facts
- Salt
- CLONAZEPAM-0.5MG+ESCITALOPRAM-5MG
- Best price
- ₹184
- MRP
- ₹194
- Prescription
- Required (Rx)
- Brand
- Intas Pharmaceuticals Ltd
- Manufacturer
- INTAS PHARMACEUTICALS`
- Therapeutic class
- Anxiolytic and hypnotic and Antidepressant
- Drug class
- Benzodiazepine / sedative-hypnotic and Antidepressant
- Habit forming
- Yes
- Variants
- NA 15`S
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
- CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Depran 5.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.