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Prescription requiredIntas Pharmaceuticals LtdNEURO CNS

Depsol 25

Imipramine (25mg)

₹15MRP ₹15In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Depsol 25 is used for bed-wetting Depression.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Imipramine (25mg)
Available variants: NA 10`S
Best price: ₹15
MRP: ₹15
Prescription: Required
Manufacturer: INTAS PHARMACEUTICALS`

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Depsol 25

Depsol 25 contains Imipramine (25mg). It belongs to the Antidepressant class of medicines.

Uses of Depsol 25

Bed-wetting Depression

Key benefits

  • In Bed-wetting Bedwetting (nocturnal enuresis) is common in children and can be distressing for both children and parents. Depsol 25mg Tablet is used to help control this condition by improving bladder control during sleep
  • reducing nighttime accidents and improving confidence. In Depression Depression is a mental health condition that affects mood
  • sleep
  • and daily functioning. Depsol 25mg Tablet helps in managing symptoms by balancing certain chemicals in the brain. It supports emotional well-being
  • enhances mood
  • and helps individuals regain interest in daily activities. Show More

How Depsol 25 works

Imipramine works by increasing the levels of certain natural chemicals (like serotonin and norepinephrine) in the brain that influence mood and emotions. It restores their balance, helps improve mood, relieves feelings of sadness, and reduces anxiety linked with depression.

How to take Depsol 25

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Depsol 25mg Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Depsol 25mg Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

If you take too much

An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Depsol 25

Most side effects of Depsol are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Depsol 25

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol UNSAFE
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

These medicines take two to four weeks to begin working, and longer for the full effect. Stopping at two weeks because nothing has changed is the commonest mistake. Never stop suddenly. Abrupt withdrawal causes dizziness, electric-shock sensations, irritability and flu-like symptoms — your doctor will reduce the dose gradually. Tell your doctor or go to hospital immediately if thoughts of harming yourself appear or worsen, particularly in the first weeks or after a dose change, and especially in anyone under twenty-five. Seek urgent care for agitation with fever, shivering, a racing heart, muscle twitching or confusion, particularly if more than one medicine affecting serotonin is being taken. Side effects are usually worst in the first fortnight and then settle.

Do not take Depsol if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

Tramadol, triptans for migraine, linezolid, St John's wort and other antidepressants can together raise serotonin dangerously. Anti-inflammatory painkillers and blood thinners increase the bleeding risk when combined with this group.

How to store Depsol 25

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Depsol 25

Depsol 25mg Tablet is used for the treatment of depression and bedwetting in children. The main dose should be taken at night as this medicine may produce drowsiness or sleepiness. You may be asked for regular blood tests to monitor the blood cell count or level of sodium and sugar in the blood. Inform your doctor if you notice behavioral changes, mood changes and suicidal thoughts while taking this medicine. Do not drive or do anything that requires concentration until you know how this medicine affects you. Do not stop taking the medication suddenly without talking to your doctor. The main dose should be taken at night as this medicine may produce drowsiness or sleepiness. It can take 2 to 3 weeks for Depsol 25mg Tablet to start working. You should continue the treatment for at least 6 months after you feel better to stop depression from coming back. If your doctor asks you to stop Depsol 25mg Tablet, you should reduce the dose slowly over 4 weeks. You should not discontinue it abruptly. Avoid driving or operating machinery as it may decrease alertness. Avoid consuming alcohol when taking the Depsol 25mg Tablet, as it may cause excessive drowsiness and calmness. The addiction/dependence potential of Depsol 25mg Tablet is very less. It may be extremely dangerous in overdose.

Manufacturer and class

Manufacturer:
INTAS PHARMACEUTICALS`
Therapeutic class:
NEURO CNS
Drug class:
Antidepressant
Chemical class:
Dibenzazepines

Substitutes for Depsol 25

Medicines with the same active ingredient (Imipramine (25mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Depsol 25
Depsonil 25 mg TabletAbbott Healthcare Pvt Ltdtablet · 10`S₹1716% more
Antidep 25 mg TabletTorrent Pharmaceuticals Ltdtablet · 10`S₹1927% more
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Depsol 25 FAQs

What is Depsol 25 used for?
Depsol 25 is commonly used for Bed-wetting Depression. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Depsol 25?
Depsol 25 contains Imipramine (25mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Depsol 25?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Depsol 25 work?
Imipramine works by increasing the levels of certain natural chemicals (like serotonin and norepinephrine) in the brain that influence mood and emotions.
Is Depsol 25 a prescription medicine?
Yes. Depsol 25 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Depsol 25?
The side effects reported most often with Depsol are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Depsol 25 be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Depsol.
Can I drink alcohol while taking Depsol 25?
Alcohol UNSAFE
What if I miss a dose of Depsol 25?
If you miss a dose of Depsol 25mg Tablet, take it as soon as possible.
Is Depsol 25 habit forming?
No. Depsol 25 is not known to be habit forming when taken as prescribed.
How much does Depsol 25 cost on PingMeDoc Pharmacy?
Depsol 25 starts at ₹15 (MRP ₹15) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Depsol 25?
Depsol 25 is manufactured by INTAS PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Depsol 25 delivered?
Depsol 25 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Depsol 25, Quick facts

Salt
Imipramine (25mg)
Best price
₹15
MRP
₹15
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Intas Pharmaceuticals Ltd
Manufacturer
INTAS PHARMACEUTICALS`
Therapeutic class
NEURO CNS
Drug class
Antidepressant
Chemical class
Dibenzazepines
Action class
Tricyclic Antidepressants (TCAs)
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

The information on Depsol 25 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Depsol 25.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.