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Prescription requiredLarenonAnti-emetic and Analgesic and anti-inflammatory

Domoxen-500 Tablet

Domperidone + Naproxen

₹114MRP ₹120In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Domoxen-500 Tablet is used for this medicine is used in the treatment of nausea, vomiting, bloating, slow stomach emptying, pain, inflammation, arthritis, fever and period pain.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Domperidone + Naproxen
Available variants: tablet 10`S
Best price: ₹114 (₹11.40 per tablet)
MRP: ₹120
Prescription: Required
Manufacturer: LARENON

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Domoxen-500 Tablet

Domoxen-500 Tablet contains Domperidone + Naproxen. It belongs to the Anti-emetic / prokinetic and Non-steroidal anti-inflammatory drug class of medicines.

Uses of Domoxen-500 Tablet

  • This medicine is used in the treatment of nausea
  • vomiting
  • bloating
  • slow stomach emptying
  • pain
  • inflammation
  • arthritis
  • fever and period pain.

Key benefits

  • Rapid relief of nausea and vomiting
  • Helps bloating and early fullness
  • Relieves pain and the swelling that causes it
  • Effective in arthritis and injury

How Domoxen-500 Tablet works

This medicine combines 2 active ingredients: Domperidone and Naproxen. Domperidone settles the stomach and blocks the signals that trigger nausea and vomiting, and helps the stomach empty at a normal rate. Naproxen blocks the chemicals your body makes at a site of injury or inflammation, which reduces pain, swelling and fever.

How to take Domoxen-500 Tablet

Swallow the tablet whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it 15 to 30 minutes before meals. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Domoxen-500 Tablet

Most side effects of Domoxen-500 are mild and settle as the body adjusts. Reported side effects include:

  • Dry mouth
  • Drowsiness
  • Headache
  • Loose motions
  • Restlessness
  • Indigestion
  • Stomach pain
  • Nausea
  • Heartburn
  • Dizziness
  • Swelling of the ankles and feet

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Domoxen-500 Tablet

PregnancyNot recommended in pregnancy — it may harm the developing baby. Tell your doctor at once if you are or might be pregnant.
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholDo not drink alcohol while taking this medicine.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyConsult your doctor if you have kidney disease.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.

Do not take Domoxen-500 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.

Interactions with other medicines

Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.

How to store Domoxen-500 Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Domoxen-500 Tablet

Take it shortly before meals for bloating and early fullness. Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting. Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache.

Manufacturer and class

Manufacturer:
LARENON
Therapeutic class:
Anti-emetic and Analgesic and anti-inflammatory
Drug class:
Anti-emetic / prokinetic and Non-steroidal anti-inflammatory drug

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Domoxen-500 Tablet FAQs

What is Domoxen-500 Tablet used for?
Domoxen-500 Tablet is commonly used for This medicine is used in the treatment of nausea, vomiting, bloating, slow stomach emptying, pain, inflammation, arthritis, fever and period pain. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Domoxen-500 Tablet?
Domoxen-500 Tablet contains Domperidone + Naproxen. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Domoxen-500 Tablet?
Swallow the tablet whole with a glass of water. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Domoxen-500 Tablet work?
This medicine combines 2 active ingredients: Domperidone and Naproxen.
Is Domoxen-500 Tablet a prescription medicine?
Yes. Domoxen-500 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Domoxen-500 Tablet?
The side effects reported most often with Domoxen-500 are Dry mouth, Drowsiness, Headache, Loose motions, Restlessness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Domoxen-500 Tablet be taken during pregnancy?
Not recommended in pregnancy — it may harm the developing baby. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Domoxen-500.
Can I drink alcohol while taking Domoxen-500 Tablet?
Do not drink alcohol while taking this medicine.
What if I miss a dose of Domoxen-500 Tablet?
Take it as soon as you remember.
Is Domoxen-500 Tablet habit forming?
No. Domoxen-500 Tablet is not known to be habit forming when taken as prescribed.
How much does Domoxen-500 Tablet cost on PingMeDoc Pharmacy?
Domoxen-500 Tablet starts at ₹114 (MRP ₹120) on PingMeDoc Pharmacy. Available in tablet 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Domoxen-500 Tablet?
Domoxen-500 Tablet is manufactured by LARENON. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Domoxen-500 Tablet delivered?
Domoxen-500 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Domoxen-500 Tablet, Quick facts

Salt
Domperidone + Naproxen
Form
tablet
Best price
₹114 (₹11.40 per tablet)
MRP
₹120
Prescription
Required (Rx)
Brand
LARENON
Manufacturer
LARENON
Therapeutic class
Anti-emetic and Analgesic and anti-inflammatory
Drug class
Anti-emetic / prokinetic and Non-steroidal anti-inflammatory drug
Habit forming
No
Variants
tablet 10`S
Delivery
Standard across India

References

The information on Domoxen-500 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Domoxen-500 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.