Ec-Pan Dsr

Composition of Ec-Pan Dsr

Ec-Pan Dsr contains Pantoprazole 40 mg (enteric-coated) + Domperidone 30 mg (sustained release) capsule. It belongs to the Proton pump inhibitor (PPI) + Prokinetic/antiemetic (D2 receptor antagonist) class of medicines.

Uses of Ec-Pan Dsr

• Gastroesophageal reflux disease (GERD)
• heartburn/acid reflux
• gastritis and indigestion associated with excess acid
• nausea/vomiting related to reflux

Key benefits

• Relieves heartburn and acid reflux
• Promotes healing in GERD/gastritis
• Reduces nausea and vomiting associated with reflux
• Improves gastric emptying and bloating

How Ec-Pan Dsr works

Pantoprazole is a proton pump inhibitor that reduces stomach acid by blocking the gastric H+/K+ ATPase pump. Domperidone is a prokinetic/antiemetic that increases gastric motility and helps reduce nausea by blocking dopamine (D2) receptors peripherally.

How to take Ec-Pan Dsr

Oral capsule. Typically taken once daily 30 minutes before food (preferably before breakfast) or as directed by physician. Swallow whole; do not crush or chew (enteric-coated/SR formulation).

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause confusion, blurred vision, sweating and a fast heartbeat. It can cause drowsiness, disorientation and abnormal muscle movements. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Ec-Pan Dsr

Most side effects of Ec-Pan Dsr are mild and settle as the body adjusts. Reported side effects include:

• Headache
• diarrhea
• abdominal pain
• nausea
• flatulence
• dizziness
• dry mouth

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Ec-Pan Dsr

Warnings and precautions

Use only on medical advice. Domperidone may prolong QT interval and cause serious heart rhythm problems; avoid in patients with known QT prolongation, significant cardiac disease, electrolyte disturbances, or with other QT-prolonging medicines. Not recommended in moderate to severe liver impairment. Long-term PPI use may be associated with low magnesium/vitamin B12, fracture risk, and increased risk of infections (e.g., C. difficile). Seek medical help for alarm symptoms (blood in vomit/stool, black stools, unexplained weight loss, persistent vomiting, severe chest pain).

Do not take Ec-Pan Dsr if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

QT-prolonging drugs (e.g., amiodarone, sotalol, certain antipsychotics/antidepressants), strong CYP3A4 inhibitors that increase domperidone levels (e.g., ketoconazole, itraconazole, clarithromycin, erythromycin, ritonavir), anticoagulants (warfarin—monitor), drugs affected by reduced acidity (e.g., ketoconazole/itraconazole absorption, iron salts), methotrexate (high dose), digoxin (monitor)

How to store Ec-Pan Dsr

Store below 25°C in a dry place, protected from light and moisture. Keep in original blister pack. Keep out of reach of children.

Expert advice for Ec-Pan Dsr

Take it before breakfast, not after a meal. Eat smaller meals, avoid late dinners, raise the head of your bed and avoid smoking — these do as much as the tablet for reflux. Take it shortly before meals for bloating and early fullness. Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting.

Manufacturer and class

Manufacturer:

ICON PHARMA

Therapeutic class:

Anti-ulcer/Anti-reflux (Gastrointestinal)

Drug class:

Proton pump inhibitor (PPI) + Prokinetic/antiemetic (D2 receptor antagonist)