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Prescription requiredSystopic LabAnti-emetic and Anti-ulcer agent

Esys D

Domperidone + Esomeprazole

₹83MRP ₹87In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

This medicine needs a prescription.

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Esys D is used for this medicine is used in the treatment of nausea, vomiting, bloating, slow stomach emptying, acidity, acid reflux, stomach ulcer and heartburn.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Domperidone + Esomeprazole
Available variants: NA 10`S
Best price: ₹83
MRP: ₹87
Prescription: Required
Manufacturer: SYSTOPIC LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Esys D

Esys D contains Domperidone + Esomeprazole. It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.

Uses of Esys D

  • This medicine is used in the treatment of nausea
  • vomiting
  • bloating
  • slow stomach emptying
  • acidity
  • acid reflux
  • stomach ulcer and heartburn.

Key benefits

  • Rapid relief of nausea and vomiting
  • Helps bloating and early fullness
  • Powerful and reliable relief of acidity
  • Heals ulcers and reflux damage
  • Usually taken once a day

How Esys D works

This medicine combines 2 active ingredients: Domperidone and Esomeprazole. Domperidone settles the stomach and blocks the signals that trigger nausea and vomiting, and helps the stomach empty at a normal rate. Esomeprazole switches off the acid pumps in the lining of your stomach, so much less acid is produced and the lining can heal.

How to take Esys D

Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Esys D

Most side effects of Esys D are mild and settle as the body adjusts. Reported side effects include:

  • Dry mouth
  • Drowsiness
  • Headache
  • Loose motions
  • Restlessness
  • Nausea
  • Stomach pain
  • Flatulence

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Esys D

PregnancyConsult your doctor before using this in pregnancy.
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholDo not drink alcohol while taking this medicine.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyUse with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.

Do not take Esys D if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.

How to store Esys D

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Esys D

Take it shortly before meals for bloating and early fullness. Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting. Take it before breakfast, not after a meal. Eat smaller meals, avoid late dinners, raise the head of your bed and avoid smoking — these do as much as the tablet for reflux.

Manufacturer and class

Manufacturer:
SYSTOPIC LAB
Therapeutic class:
Anti-emetic and Anti-ulcer agent
Drug class:
Anti-emetic / prokinetic and Proton pump inhibitor

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Esys D FAQs

What is Esys D used for?
Esys D is commonly used for This medicine is used in the treatment of nausea, vomiting, bloating, slow stomach emptying, acidity, acid reflux, stomach ulcer and heartburn. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Esys D?
Esys D contains Domperidone + Esomeprazole. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Esys D?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Esys D work?
This medicine combines 2 active ingredients: Domperidone and Esomeprazole.
Is Esys D a prescription medicine?
Yes. Esys D is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Esys D?
The side effects reported most often with Esys D are Dry mouth, Drowsiness, Headache, Loose motions, Restlessness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Esys D be taken during pregnancy?
Consult your doctor before using this in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Esys D.
Can I drink alcohol while taking Esys D?
Do not drink alcohol while taking this medicine.
What if I miss a dose of Esys D?
Take it as soon as you remember.
Is Esys D habit forming?
No. Esys D is not known to be habit forming when taken as prescribed.
How much does Esys D cost on PingMeDoc Pharmacy?
Esys D starts at ₹83 (MRP ₹87) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Esys D?
Esys D is manufactured by SYSTOPIC LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Esys D delivered?
Esys D is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Esys D, Quick facts

Salt
Domperidone + Esomeprazole
Best price
₹83
MRP
₹87
Prescription
Required (Rx)
Brand
SYSTOPIC LAB
Manufacturer
SYSTOPIC LAB
Therapeutic class
Anti-emetic and Anti-ulcer agent
Drug class
Anti-emetic / prokinetic and Proton pump inhibitor
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

The information on Esys D is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Esys D.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.