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Prescription requiredFranco-indian PharmaceuticalsAnti-emetic and Anti-ulcer agent

GR8

Domperidone (10mg) + Omeprazole (20mg)

₹95MRP ₹1005% offIn stock
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GR8 is used for gR8 Capsule is used in the treatment of acidity and heartburn.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Domperidone (10mg) + Omeprazole (20mg)
Available variants: NA 10`S
Best price: ₹95
MRP: ₹100
Prescription: Required
Manufacturer: FRANCO-INDIAN PHARMACEUTICALS

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of GR8

GR8 contains Domperidone (10mg) + Omeprazole (20mg). It belongs to the Anti-emetic / prokinetic and Proton pump inhibitor class of medicines.

Uses of GR8

GR8 Capsule is used in the treatment of acidity and heartburn.

Key benefits

  • Rapid relief of nausea and vomiting
  • Helps bloating and early fullness
  • Powerful and reliable relief of acidity
  • Heals ulcers and reflux damage
  • Usually taken once a day

How GR8 works

GR8 Capsule is a combination of two medicines: Domperidone and Omeprazole. Domperidone is a prokinetic which works on the upper digestive tract to increase the movement of the stomach and intestines, allowing the food to move more easily through the stomach. Omeprazole is a proton pump inhibitor (PPI) which works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.

How to take GR8

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. GR8 Capsule is to be taken empty stomach.<br>Take GR8 Capsule 30 minutes before food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It may cause confusion, blurred vision, sweating and a fast heartbeat. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of GR8

Most side effects of GR8 are mild and settle as the body adjusts. Reported side effects include:

  • Diarrhea Stomach pain Dryness in mouth Headache Flatulence

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for GR8

PregnancyGR8 Capsule may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingGR8 Capsule is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
AlcoholTaking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn. This would decrease the effect of this drug and can aggravate your underlying condition.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyGR8 Capsule should be used with caution in patients with kidney disease. Dose adjustment of GR8 Capsule may be needed. Please consult your doctor.
LiverGR8 Capsule should be used with caution in patients with liver disease. Dose adjustment of GR8 Capsule may be needed. Please consult your doctor.<br>Use of GR8 Capsule is not recommended in patients with moderate and severe liver disease.
Habit formingNo

Warnings and precautions

Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Take it on an empty stomach, about half an hour to an hour before your first meal — this is when the acid pumps are most active and the medicine works best. Long-term use has been linked to low magnesium and low vitamin B12, and to a higher risk of bone fracture. Review the need with your doctor rather than continuing indefinitely. Tell your doctor if acidity comes with difficulty swallowing, vomiting, weight loss, or black stools — these need investigation, not a longer course. Do not stop a long course abruptly; acid can rebound. Your doctor will taper it.

Do not take GR8 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Reduces the absorption of some antifungals, iron and certain HIV medicines. Tell your doctor if you take clopidogrel, methotrexate or a blood thinner.

How to store GR8

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for GR8

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>You have been prescribed GR8 Capsule for the treatment of acidity and heartburn.</li> <li>Take it one hour before the meal, preferably in the morning.</li> <li>It is a well-tolerated medicine and provides relief for a long time.</li> <li>Inform your doctor if you get watery diarrhea, fever or stomach pain that does not go away.</li> <li>Inform your doctor if you do not feel better after taking it for 14 days as you may be suffering from some other problem that needs attention.</li> <li>Long-term use can cause weak bones and deficiency of minerals such as magnesium. Take adequate dietary intake of calcium and magnesium or their supplements as prescribed by your doctor.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
FRANCO-INDIAN PHARMACEUTICALS
Therapeutic class:
Anti-emetic and Anti-ulcer agent
Drug class:
Anti-emetic / prokinetic and Proton pump inhibitor

Substitutes for GR8

Medicines with the same active ingredient (Domperidone (10mg) + Omeprazole (20mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs GR8
Kzole D CapsuleKALPA HEALTH CARE PVT LTDcapsule · 15`S₹10712% more
Omee D CapsuleCOMMON PRODUCTScapsule · 20`S₹15664% more
Omee D Capsule20'S₹19099% more
Promisec D Capsule1X20₹237148% more
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GR8 FAQs

What is GR8 used for?
GR8 is commonly used for GR8 Capsule is used in the treatment of acidity and heartburn. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in GR8?
GR8 contains Domperidone (10mg) + Omeprazole (20mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take GR8?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does GR8 work?
GR8 Capsule is a combination of two medicines: Domperidone and Omeprazole.
Is GR8 a prescription medicine?
Yes. GR8 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of GR8?
The side effects reported most often with GR8 are Diarrhea Stomach pain Dryness in mouth Headache Flatulence. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can GR8 be taken during pregnancy?
GR8 Capsule may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting GR8.
Can I drink alcohol while taking GR8?
Taking a large amount of alcohol can increase acidity and cause acid reflux in the food pipe causing heartburn.
What if I miss a dose of GR8?
Take it as soon as you remember.
Is GR8 habit forming?
No. GR8 is not known to be habit forming when taken as prescribed.
How much does GR8 cost on PingMeDoc Pharmacy?
GR8 starts at ₹95 (MRP ₹100) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures GR8?
GR8 is manufactured by FRANCO-INDIAN PHARMACEUTICALS. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is GR8 delivered?
GR8 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

GR8, Quick facts

Salt
Domperidone (10mg) + Omeprazole (20mg)
Best price
₹95
MRP
₹100
Prescription
Required (Rx)
Schedule
Schedule H
Brand
FRANCO-INDIAN PHARMACEUTICALS
Manufacturer
FRANCO-INDIAN PHARMACEUTICALS
Therapeutic class
Anti-emetic and Anti-ulcer agent
Drug class
Anti-emetic / prokinetic and Proton pump inhibitor
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for GR8.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.