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Prescription requiredLupin LabMuscle relaxant and Analgesic and anti-inflammatory

Lupiflex 4

Thiocolchicoside (4mg) + Ketoprofen (50mg)

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Lupiflex 4 is used for lupiflex 4 Tablet is used in pain due to muscle spasm.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Thiocolchicoside (4mg) + Ketoprofen (50mg)
Available variants: NA 10`S
Best price: ₹166
MRP: ₹175
Prescription: Required
Manufacturer: LUPIN LAB

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Lupiflex 4

Lupiflex 4 contains Thiocolchicoside (4mg) + Ketoprofen (50mg). It belongs to the Centrally acting muscle relaxant and Non-steroidal anti-inflammatory drug class of medicines.

Uses of Lupiflex 4

Lupiflex 4 Tablet is used in pain due to muscle spasm.

Key benefits

  • Breaks the spasm–pain cycle
  • Helps you move and sleep more comfortably
  • Relieves pain and the swelling that causes it
  • Effective in arthritis and injury

How Lupiflex 4 works

Lupiflex 4 Tablet is a combination of two medicines: Ketoprofen and Thiocolchicoside which relieve pain and relax the muscles. Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Thiocolchicoside is a muscle relaxant. It works by acting on the centers in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.

How to take Lupiflex 4

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupiflex 4 Tablet is to be taken with food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause deep drowsiness, muscle weakness, a fall in blood pressure and slowed breathing. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lupiflex 4

Most side effects of Lupiflex are mild and settle as the body adjusts. Reported side effects include:

  • Nausea Indigestion Heartburn Stomach pain

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lupiflex 4

PregnancyLupiflex 4 Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingNo information is available on the use of Lupiflex 4 Tablet during lactation. Please consult your doctor.
AlcoholTaking Ketoprofen with alcohol increases the risk of stomach bleeding.
DrivingDo not drive or operate machinery while taking this medicine.
KidneyLupiflex 4 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lupiflex 4 Tablet may be needed. Please consult your doctor.<br>Regular monitoring of kidney function test is advised while you are taking this medicine. Use of Lupiflex 4 Tablet is not recommended in patients with severe kidney disease.
LiverThere is limited information available on the use of Lupiflex 4 Tablet in patients with liver disease. Please consult your doctor.
Habit formingNo

Warnings and precautions

This medicine causes drowsiness. Do not drive or operate machinery until you know how it affects you. Use it for the short course your doctor has prescribed — these are not intended for long-term use. Do not stop a long course abruptly without asking your doctor. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.

Do not take Lupiflex if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with myasthenia gravis or severe liver disease. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.

Interactions with other medicines

Alcohol, sleeping tablets, antihistamines and opioid painkillers all add to the drowsiness, sometimes dangerously. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.

How to store Lupiflex 4

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Lupiflex 4

Combine it with gentle movement and the physiotherapy your doctor advises; rest alone prolongs back pain. Take it at night if drowsiness troubles you during the day. Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache.

Manufacturer and class

Manufacturer:
LUPIN LAB
Therapeutic class:
Muscle relaxant and Analgesic and anti-inflammatory
Drug class:
Centrally acting muscle relaxant and Non-steroidal anti-inflammatory drug

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Lupiflex 4 FAQs

What is Lupiflex 4 used for?
Lupiflex 4 is commonly used for Lupiflex 4 Tablet is used in pain due to muscle spasm. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Lupiflex 4?
Lupiflex 4 contains Thiocolchicoside (4mg) + Ketoprofen (50mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Lupiflex 4?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Lupiflex 4 work?
Lupiflex 4 Tablet is a combination of two medicines: Ketoprofen and Thiocolchicoside which relieve pain and relax the muscles.
Is Lupiflex 4 a prescription medicine?
Yes. Lupiflex 4 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Lupiflex 4?
The side effects reported most often with Lupiflex are Nausea Indigestion Heartburn Stomach pain. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Lupiflex 4 be taken during pregnancy?
Lupiflex 4 Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Lupiflex.
Can I drink alcohol while taking Lupiflex 4?
Taking Ketoprofen with alcohol increases the risk of stomach bleeding.
What if I miss a dose of Lupiflex 4?
Take it as soon as you remember.
Is Lupiflex 4 habit forming?
No. Lupiflex 4 is not known to be habit forming when taken as prescribed.
How much does Lupiflex 4 cost on PingMeDoc Pharmacy?
Lupiflex 4 starts at ₹166 (MRP ₹175) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Lupiflex 4?
Lupiflex 4 is manufactured by LUPIN LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Lupiflex 4 delivered?
Lupiflex 4 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Lupiflex 4, Quick facts

Salt
Thiocolchicoside (4mg) + Ketoprofen (50mg)
Best price
₹166
MRP
₹175
Prescription
Required (Rx)
Schedule
Schedule H
Brand
LUPIN LAB
Manufacturer
LUPIN LAB
Therapeutic class
Muscle relaxant and Analgesic and anti-inflammatory
Drug class
Centrally acting muscle relaxant and Non-steroidal anti-inflammatory drug
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

The information on Lupiflex 4 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Lupiflex 4.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.