
Ab Flo Caps
Lupin Lab - Capsule - 100mg - 15 S
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Thiocolchicoside (4mg) + Ketoprofen (50mg)
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Lupiflex 4 is used for lupiflex 4 Tablet is used in pain due to muscle spasm.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Lupiflex 4 contains Thiocolchicoside (4mg) + Ketoprofen (50mg). It belongs to the Centrally acting muscle relaxant and Non-steroidal anti-inflammatory drug class of medicines.
Lupiflex 4 Tablet is used in pain due to muscle spasm.
Lupiflex 4 Tablet is a combination of two medicines: Ketoprofen and Thiocolchicoside which relieve pain and relax the muscles. Ketoprofen is a non-steroidal anti-inflammatory drug (NSAID) which works by blocking the release of certain chemical messengers that cause pain and inflammation (redness and swelling). Thiocolchicoside is a muscle relaxant. It works by acting on the centers in the brain and spinal cord to relieve muscle stiffness or spasm and to improve pain and movement of muscles.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Lupiflex 4 Tablet is to be taken with food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause deep drowsiness, muscle weakness, a fall in blood pressure and slowed breathing. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Lupiflex are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Lupiflex 4 Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | No information is available on the use of Lupiflex 4 Tablet during lactation. Please consult your doctor. |
| Alcohol | Taking Ketoprofen with alcohol increases the risk of stomach bleeding. |
| Driving | Do not drive or operate machinery while taking this medicine. |
| Kidney | Lupiflex 4 Tablet should be used with caution in patients with kidney disease. Dose adjustment of Lupiflex 4 Tablet may be needed. Please consult your doctor.<br>Regular monitoring of kidney function test is advised while you are taking this medicine. Use of Lupiflex 4 Tablet is not recommended in patients with severe kidney disease. |
| Liver | There is limited information available on the use of Lupiflex 4 Tablet in patients with liver disease. Please consult your doctor. |
| Habit forming | No |
This medicine causes drowsiness. Do not drive or operate machinery until you know how it affects you. Use it for the short course your doctor has prescribed — these are not intended for long-term use. Do not stop a long course abruptly without asking your doctor. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with myasthenia gravis or severe liver disease. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.
Alcohol, sleeping tablets, antihistamines and opioid painkillers all add to the drowsiness, sometimes dangerously. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Combine it with gentle movement and the physiotherapy your doctor advises; rest alone prolongs back pain. Take it at night if drowsiness troubles you during the day. Use the lowest dose for the shortest period. If you need a painkiller regularly, see your doctor rather than continuing on your own. Paracetamol is the safer choice for simple fever and headache.

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The information on Lupiflex 4 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.