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OTC · No prescriptionLupin LabRESPIRATORY

Lupihist 100 ml

Diphenhydramine (15mg) + Ammonium Chloride (150mg) + Sodium Citrate (85mg)

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Lupihist 100 ml is used for treatment of Cough.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Diphenhydramine (15mg) + Ammonium Chloride (150mg) + Sodium Citrate (85mg)
Available variants: 100 ml 100ML
Best price: ₹71 (₹0.71 per ml)
MRP: ₹75
Prescription: Not required
Manufacturer: LUPIN LAB

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Lupihist 100 ml

Lupihist 100 ml contains Diphenhydramine (15mg) + Ammonium Chloride (150mg) + Sodium Citrate (85mg). It belongs to the Antihistamine / leukotriene antagonist, Expectorant / mucolytic / bronchodilator and Laxative class of medicines.

Uses of Lupihist 100 ml

Treatment of Cough

Key benefits

  • In Treatment of Cough Lupihist Syrup is a combination medicine that helps relieve cough and associated symptoms. It works by loosening thick mucus
  • making it easier to cough out
  • and clearing the airways. It also reduces allergy-related symptoms such as sneezing
  • runny nose
  • watery eyes
  • and throat irritation. This helps improve breathing and provides overall comfort.

How Lupihist 100 ml works

Lupihist Syrup is a combination of three medicines: diphenhydramine, ammonium chloride, and sodium citrate. Diphenhydramine is an antihistamine that relieves allergy symptoms such as a runny nose, watery eyes, and sneezing. Ammonium chloride is an expectorant that helps loosen mucus (phlegm) and make it easier to remove from the airways. Sodium citrate helps thin and loosen mucus, making it easier to cough out.

How to take Lupihist 100 ml

Take this medicine in the dose and duration as advised by your doctor. Check the label for directions before use. Measure it with a measuring cup and take it by mouth. Shake well before use. Lupihist Syrup may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Lupihist Syrup, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause severe drowsiness, a fast heartbeat, confusion and, in children, agitation and fits. It can cause vomiting, severe drowsiness, a racing heart and, with codeine, dangerously slow breathing. It can cause severe loose motions, dehydration and salt imbalance. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Lupihist 100 ml

Most side effects of Lupihist are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Lupihist 100 ml

PregnancyPregnancy UNSAFE
BreastfeedingBreast feeding CAUTION
AlcoholAlcohol UNSAFE
DrivingDriving UNSAFE
KidneyKidney UNSAFE
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

Older antihistamines cause marked drowsiness — do not drive or operate machinery until you know how this affects you. Tell your doctor promptly about any change in mood, sleep, agitation or unusual thoughts while taking montelukast; this is uncommon but recognised. This relieves the symptoms of an allergy; it does not treat the cause, and it is not a treatment for an acute asthma attack. Seek emergency care for swelling of the lips, tongue or throat, or difficulty breathing. See a doctor if a cough lasts more than a week, or comes with fever, breathlessness, chest pain or blood in the sputum. Do not give cough and cold preparations to young children except on a doctor's advice. Do not combine two cough preparations — they frequently contain the same ingredients, and the doses add up. Preparations containing codeine can cause dependence and must be used only for the period your doctor specifies. Drink plenty of water while taking any laxative, particularly the fibre-based ones — without it they can make constipation worse. Do not use stimulant laxatives daily over long periods without medical advice; the bowel becomes reliant on them. See a doctor if constipation is new and persistent in an adult over forty, or comes with blood, weight loss or severe pain.

Do not take Lupihist if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. The sedating antihistamines are not suitable for very young children, or for people with glaucoma or an enlarged prostate, without medical advice. Codeine-containing preparations are not for children, or for anyone with breathing difficulty. Not for anyone with a suspected bowel obstruction, or with severe abdominal pain of unknown cause.

Interactions with other medicines

Alcohol, sleeping tablets and other sedating medicines add to the drowsiness. Tell your doctor about all cold and cough preparations — many already contain an antihistamine. Sedating ingredients add to the effect of alcohol and sleeping tablets. Decongestants such as phenylephrine and pseudoephedrine can raise blood pressure — tell your doctor if you are hypertensive. Laxatives can reduce the absorption of other medicines taken at the same time.

How to store Lupihist 100 ml

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Lupihist 100 ml

Lupihist Syrup may cause dizziness or sleepiness, so avoid driving or operating machinery until you know how it affects you. Avoid alcohol or other sedating medicines while taking Lupihist Syrup, as they may increase drowsiness. Use a proper measuring cup or spoon to measure the dose, not a household tablespoon. Dry mouth or constipation may occur; staying hydrated and maintaining fiber intake may help. Do not combine Lupihist Syrup with other cough or cold medicines containing antihistamines or sedatives unless advised by your doctor. If you have diabetes, monitor your blood glucose levels while taking Lupihist Syrup. Inform your doctor if you have a history of thyroid disease, heart disease, glaucoma, or urinary retention before using Lupihist Syrup. Avoid smoking or exposure to secondhand smoke, as it may worsen cough and throat irritation. Seek medical attention if you develop a high fever, chest pain, breathlessness, or cough up blood. Stop taking Lupihist Syrup and consult your doctor if cough lasts more than about one week, keeps recurring, or occurs with fever, rash, or persistent headache. Stop the medicine and seek urgent medical help if rash, swelling of the face, or breathing difficulty occurs.

Manufacturer and class

Manufacturer:
LUPIN LAB
Therapeutic class:
RESPIRATORY
Drug class:
Antihistamine / leukotriene antagonist, Expectorant / mucolytic / bronchodilator and Laxative

Substitutes for Lupihist 100 ml

Medicines with the same active ingredient (Diphenhydramine (15mg) + Ammonium Chloride (150mg) + Sodium Citrate (85mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Lupihist 100 ml
Aristodryl 100 ml Syrup100ML₹12372% more
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Lupihist 100 ml FAQs

What is Lupihist 100 ml used for?
Lupihist 100 ml is commonly used for Treatment of Cough. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Lupihist 100 ml?
Lupihist 100 ml contains Diphenhydramine (15mg) + Ammonium Chloride (150mg) + Sodium Citrate (85mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Lupihist 100 ml?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Lupihist 100 ml work?
Lupihist Syrup is a combination of three medicines: diphenhydramine, ammonium chloride, and sodium citrate.
Is Lupihist 100 ml a prescription medicine?
No. Lupihist 100 ml is available over the counter (OTC), no prescription is required. However, it is always safer to consult a doctor or pharmacist before use.
What are the common side effects of Lupihist 100 ml?
The side effects reported most often with Lupihist are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Lupihist 100 ml be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Lupihist.
Can I drink alcohol while taking Lupihist 100 ml?
Alcohol UNSAFE
What if I miss a dose of Lupihist 100 ml?
If you miss a dose of Lupihist Syrup, take it as soon as possible.
Is Lupihist 100 ml habit forming?
No. Lupihist 100 ml is not known to be habit forming when taken as prescribed.
How much does Lupihist 100 ml cost on PingMeDoc Pharmacy?
Lupihist 100 ml starts at ₹71 (MRP ₹75) on PingMeDoc Pharmacy. Available in 100 ml 100ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Lupihist 100 ml?
Lupihist 100 ml is manufactured by LUPIN LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Lupihist 100 ml delivered?
Lupihist 100 ml is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Lupihist 100 ml, Quick facts

Salt
Diphenhydramine (15mg) + Ammonium Chloride (150mg) + Sodium Citrate (85mg)
Best price
₹71 (₹0.71 per ml)
MRP
₹75
Prescription
Not required (OTC)
Brand
LUPIN LAB
Manufacturer
LUPIN LAB
Therapeutic class
RESPIRATORY
Drug class
Antihistamine / leukotriene antagonist, Expectorant / mucolytic / bronchodilator and Laxative
Habit forming
No
Variants
100 ml 100ML
Delivery
Standard across India

References

Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Lupihist 100 ml.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.