
Aceclo 100MG
Aristo Pharmaceuticals Pvt Ltd - 100 mg - 10 S
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Ampicillin + Cloxacillin
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Megapen 1 g Injection Vial is used for this medicine is used in the treatment of bacterial infection, throat infection, chest infection, skin infection and urinary infection.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Megapen 1 g Injection Vial contains Ampicillin + Cloxacillin. It belongs to the Penicillin class of medicines.
Megapen 1 gm Injection is a combination of two antibiotics: Ampicillin and Cloxacillin. These antibiotics work by preventing the formation of the bacterial protective covering which is essential for the survival of bacteria. Together, they treat your infection effectively.
This is given by a doctor or a nurse. Do not attempt to inject it yourself unless you have been trained and told to. Follow the dose and the duration written on your prescription.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause vomiting, severe loose motions and, rarely, fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Megapen are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Megapen 1 gm Injection is probably safe to use during pregnancy.<br>Animal studies have shown low or no adverse effect on the foetus, however, there are limited human studies. Please consult your doctor. |
|---|---|
| Breastfeeding | Megapen 1 gm Injection is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. |
| Alcohol | Interaction with alcohol is unknown. Please consult your doctor. |
| Driving | Not expected to affect your ability to drive. |
| Kidney | Megapen 1 gm Injection should be used with caution in patients with kidney disease. Dose adjustment of Megapen 1 gm Injection may be needed. Please consult your doctor.<br>Regular monitoring of kidney function tests is advised while taking this medicine. |
| Liver | Megapen 1 gm Injection should be used with caution in patients with liver disease. Dose adjustment of Megapen 1 gm Injection may be needed. Please consult your doctor.<br>Regular monitoring of liver function tests is advised while taking this medicine. |
| Habit forming | No |
Finish the whole course even after you feel better. Stopping early lets the strongest bacteria survive, and they are the ones that come back resistant. Stop and seek emergency care for swelling of the face or throat, difficulty breathing, or a widespread rash — a penicillin allergy can be serious. Tell every doctor and pharmacist if you have ever reacted to penicillin. Tell your doctor if loose motions become severe or watery, or continue after the course — this needs attention rather than an anti-diarrhoeal. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known penicillin allergy.
May reduce the reliability of the oral contraceptive pill if you have vomiting or loose motions — use additional precautions during the course. Tell your doctor if you take methotrexate or a blood thinner.
Store as printed on the carton — some injections need refrigeration and must not be frozen. Keep out of the reach of children.
Space the doses evenly through the day so the level stays steady. Take a probiotic a few hours apart if loose motions trouble you, and drink plenty of fluids. Never use a leftover antibiotic, or someone else's, for a new illness.

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The information on Megapen 1 g Injection Vial is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.