Amitop M 5MG Tab
Tasmed India Pvt Ltd - Tablet - 5 mg - 15 S
Domperidone (10mg) + Paracetamol (325mg)
Motidom P Tablet is used for motidom P Tablet is used in the treatment of migraine.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Motidom P Tablet contains Domperidone (10mg) + Paracetamol (325mg). It belongs to the Anti-emetic / prokinetic and Para-aminophenol derivative class of medicines.
Motidom P Tablet is used in the treatment of migraine.
Motidom P Tablet is a combination of two medicines: Domperidone and Paracetamol/Acetaminophen. Domperidone is a prokinetic which works on the region in the brain that controls vomiting. It also increases the movement of the stomach and intestines, allowing food to move more easily through the stomach. This prevents nausea and vomiting caused due to migraine. Paracetamol/Acetaminophen is an analgesic (pain reliever) and an anti-pyretic (fever reducer) which blocks the release of certain chemical messengers that cause pain and fever associated with migraine.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Motidom P Tablet is to be taken empty stomach.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
An overdose of this medicine can cause drowsiness, disorientation and abnormal muscle movements. It can cause severe and sometimes fatal liver damage, often with no symptoms at all for the first day. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Motidom P are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Motidom P Tablet may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Motidom P Tablet is safe to use during lactation. Human studies have shown that either the drug does not pass into the breastmilk in significant amount or is not expected to cause toxicity to the baby. |
| Alcohol | Taking Domperidone+Paracetamol/Acetaminophen with alcohol can cause liver damage. |
| Driving | May cause drowsiness or affect your concentration. Do not drive until you know how it affects you. |
| Kidney | Motidom P Tablet should be used with caution in patients with kidney disease. Dose adjustment of Motidom P Tablet may be needed. Please consult your doctor. |
| Liver | Motidom P Tablet should be used with caution in patients with liver disease. Dose adjustment of Motidom P Tablet may be needed. Please consult your doctor.<br>However, the use of Motidom P Tablet is not recommended in patients with severe liver disease and active liver disease. |
| Habit forming | No |
Use it for the shortest period that works. These medicines are not intended for long-term daily use. Report any unusual muscle stiffness, tremor, restlessness or uncontrolled movements of the face or limbs at once — stop and contact your doctor. Tell your doctor if you have a heart rhythm problem; some of this group affect the heart's electrical timing. Persistent vomiting needs a diagnosis. Do not keep suppressing it without seeing a doctor, especially with abdominal pain, fever or blood. Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders. Not for people with severe liver disease, except under medical supervision.
Antifungals, some antibiotics and heart-rhythm medicines increase the risk of rhythm problems when combined. Adds to the drowsiness of alcohol and sedatives. Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
Take it shortly before meals for bloating and early fullness. Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting. Take the lowest dose that works, and leave the stated gap between doses. Seek help immediately after a suspected overdose, even if you feel completely well — treatment works best when it is early.
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The information on Motidom P Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.