Myotop Dsr Tablet

Composition of Myotop Dsr Tablet

Myotop Dsr Tablet contains Tolperisone (450mg) + Diclofenac (100mg). It belongs to the Proton pump inhibitor (esomeprazole) + dopamine D2 antagonist prokinetic/antiemetic (domperidone) class of medicines.

Uses of Myotop Dsr Tablet

• Gastroesophageal reflux disease (GERD)
• heartburn and acid reflux
• gastritis/acid-peptic disorders
• nausea and vomiting associated with reflux or delayed gastric emptying

Key benefits

• Relieves heartburn and acid reflux
• Promotes healing in acid-peptic disease
• Reduces nausea and bloating
• Improves gastric emptying and reflux symptoms

How Myotop Dsr Tablet works

Esomeprazole is a proton pump inhibitor that reduces stomach acid by blocking the gastric H+/K+ ATPase pump. Domperidone is a peripheral dopamine (D2) receptor antagonist that enhances gastric motility and helps relieve nausea by improving gastric emptying.

How to take Myotop Dsr Tablet

Take as directed by the physician, usually 1 tablet once daily before food (preferably 30 minutes before breakfast). Swallow whole with water; do not crush or chew as it is a DSR (delayed release + sustained release) formulation.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Myotop-DSR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause deep drowsiness, muscle weakness, a fall in blood pressure and slowed breathing. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Myotop Dsr Tablet

Most side effects of Myotop Dsr are mild and settle as the body adjusts. Reported side effects include:

• Headache
• diarrhoea
• abdominal pain
• nausea
• dry mouth
• flatulence
• dizziness
• constipation

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Myotop Dsr Tablet

Warnings and precautions

Use with caution in liver disease; domperidone is not recommended in moderate to severe hepatic impairment. Domperidone may increase risk of serious heart rhythm problems (QT prolongation/arrhythmia), especially in older adults, with higher doses, or with interacting medicines—seek medical help for palpitations, fainting, or chest discomfort. Avoid in patients with known QT prolongation, significant electrolyte disturbances, or concomitant QT-prolonging drugs. Long-term PPI use may be associated with low magnesium, vitamin B12 deficiency, bone fracture risk and infections; use the lowest effective dose. Not for use if there is GI bleeding, obstruction or perforation.

Do not take Myotop Dsr if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with myasthenia gravis or severe liver disease. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.

Interactions with other medicines

QT-prolonging drugs (e.g., amiodarone,sotalol,quinidine),macrolide antibiotics (erythromycin,clarithromycin),azole antifungals (ketoconazole,itraconazole,fluconazole),HIV protease inhibitors (ritonavir),CYP3A4 inhibitors,warfarin (monitor INR),clopidogrel (reduced effect possible with some PPIs),digoxin (levels may increase),methotrexate (high-dose),tacrolimus

How to store Myotop Dsr Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Expert advice for Myotop Dsr Tablet

Myotop-DSR Tablet helps relieve pain and muscle spasm that may occur due to strains, sprains, and muscle injuries. It is usually used along with rest and physical therapy. Take it with food to avoid an upset stomach. It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you. Avoid consuming alcohol when taking Myotop-DSR Tablet as it may cause excessive drowsiness.

Manufacturer and class

Manufacturer:

ZUVENTUS HEALTHCARE LTD`

Therapeutic class:

Anti-ulcer/Anti-reflux (PPI + prokinetic)

Drug class:

Proton pump inhibitor (esomeprazole) + dopamine D2 antagonist prokinetic/antiemetic (domperidone)