
Amoclafix 625MG Tab
Klm Lab - Tablet - 625 mg - 10 S
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Clobetasol (0.05%w/w) + Salicylic Acid (3%w/w)
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Niosalic Ointment is used for niosalic Ointment is used in the treatment of eczema and psoriasis.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Medicines with the same active ingredient and strength as Niosalic Ointment.
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Niosalic Ointment
ointment - 0.05%w/w + 3%w/w - 20 g
₹170
₹8.50 per g
SYSTOPIC LAB · ointment - 0.05%w/w + 3%w/w - 30 g · Rx
₹116
₹3.86 per g
20 g · Rx
₹81
₹4.04 per g
EAST WEST PHARMA · ointment - 0.05%w/w + 3%w/w - 15 g · Rx
₹103
₹6.84 per g
A substitute contains the same active ingredient (salt), in the same strength, as Niosalic Ointment. The medicine inside is the same — the brand name, manufacturer and price are what differ.
All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.
Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.
Niosalic Ointment contains Clobetasol (0.05%w/w) + Salicylic Acid (3%w/w). It belongs to the Corticosteroid / calcineurin inhibitor and Retinoid / keratolytic class of medicines.
Niosalic Ointment is used in the treatment of eczema and psoriasis.
Niosalic Ointment is a combination of two medicines: Clobetasol and Salicylic Acid, which treats eczema and psoriasis. Clobetasol is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Salicylic Acid is a keratolytic medicine which breaks down keratin clumps, removes dead skin cells and softens the skin. It also enhances the absorption of Clobetasol into the skin.
This medicine is for external use only. Use it in the dose and duration as advised by your doctor. Check the label for directions before use. Clean and dry the affected area and gently massage the ointment. Wash your hands after applying, unless hands are the affected area.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.
An overdose of this medicine can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. It can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Niosalic are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Niosalic Ointment may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. |
|---|---|
| Breastfeeding | Niosalic Ointment is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby. |
| Alcohol | No interaction found/established |
| Driving | Not expected to affect your ability to drive. |
| Kidney | No interaction found/established |
| Liver | No interaction found/established |
| Habit forming | No |
Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted. Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy.
No significant interactions are expected from preparations used on the skin. Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics.
Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.
Apply a thin layer — a fingertip's worth covers an area about the size of two adult palms. Use a plain moisturiser generously alongside it; that is what keeps eczema away between flares. Ask your doctor for a written plan of how long to use it and when to step down. Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars.
Medicines with the same active ingredient (Clobetasol (0.05%w/w) + Salicylic Acid (3%w/w)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Niosalic Ointment |
|---|---|---|---|
| Diplomax Ointment 20 g | 20gm | ₹81 | 53% cheaper |
| Clomic S OintmentEAST WEST PHARMA | ointment · 15GM | ₹103 | 40% cheaper |
| Topisal 3% OinSYSTOPIC LAB | ointment · 30GM | ₹116 | 32% cheaper |
| Topisal 3 Lotion | lotion · 50 Ml | ₹134 | 21% cheaper |
| Dipsalic F Ointment 30 gAbbott Healthcare Pvt Ltd | ointment · 30GM | ₹243 | 43% more |

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Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered medical practitioner. It does not replace your own doctor's advice.