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OTC · No prescriptionGlaxoSmithKline Consumer Pvt LtdNasal decongestant

Otrivin Advance Adult Nasal Spray

Xylometazoline hydrochloride 0.1% w/v (1 mg/mL) nasal spray

Otrivin Advance Adult Nasal Spray is used for relief of nasal congestion due to common cold, allergic rhinitis (hay fever), sinusitis; may help open blocked nose and improve breathing.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹240₹24.00 per g
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Xylometazoline hydrochloride 0.1% w/v (1 mg/mL) nasal spray
Available variants: spray 10 Gm
Best price: ₹240 (₹24.00 per g)
Prescription: Not required
Manufacturer: GlaxoSmithKline Consumer Pvt Ltd

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Otrivin Advance Adult Nasal Spray

Otrivin Advance Adult Nasal Spray contains Xylometazoline hydrochloride 0.1% w/v (1 mg/mL) nasal spray. It belongs to the Topical alpha-adrenergic agonist (imidazoline derivative) class of medicines.

Uses of Otrivin Advance Adult Nasal Spray

  • Relief of nasal congestion due to common cold
  • allergic rhinitis (hay fever)
  • sinusitis; may help open blocked nose and improve breathing

Key benefits

  • Fast relief from blocked nose
  • Reduces nasal swelling
  • Improves airflow and breathing
  • Helps relieve congestion from cold/allergies/sinusitis

How Otrivin Advance Adult Nasal Spray works

Xylometazoline is an alpha-adrenergic agonist that constricts blood vessels in the nasal mucosa. This reduces swelling and mucus congestion, improving airflow through the nose.

How to take Otrivin Advance Adult Nasal Spray

For adults and adolescents ≥12 years: 1 spray in each nostril up to 2-3 times daily as needed. Use for a maximum of 3 consecutive days unless advised by a doctor. Blow nose before use; keep bottle upright and avoid sharing the spray.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine may cause a racing heart, restlessness and a rise in blood pressure if swallowed. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Otrivin Advance Adult Nasal Spray

Most side effects of Otrivin Advance Adult Nasal are mild and settle as the body adjusts. Reported side effects include:

  • Nasal dryness
  • burning or stinging in nose/throat
  • sneezing
  • irritation
  • headache
  • nausea
  • palpitations
  • rebound congestion (with overuse)

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Otrivin Advance Adult Nasal Spray

PregnancyConsult doctor
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholNo known interaction
DrivingNot expected to affect your ability to drive.
KidneyNo dose change is usually needed in kidney disease.
LiverNo dose change is usually needed in liver disease.
Habit formingNo

Warnings and precautions

Do not use for more than 3 days (risk of rebound congestion/rhinitis medicamentosa). Use with caution in hypertension, heart disease, hyperthyroidism, diabetes, enlarged prostate, glaucoma. Avoid in atrophic rhinitis or after certain nasal surgeries unless prescribed. Seek medical advice if symptoms persist/worsen. Not recommended for children <12 years for this strength. Do not exceed recommended dose.

Do not take Otrivin Advance Adult Nasal if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Decongestant sprays are not suitable for very young children without medical advice.

Interactions with other medicines

MAO inhibitors (or within 14 days), tricyclic antidepressants, other sympathomimetics/decongestants, certain antihypertensives (may reduce control of blood pressure)

How to store Otrivin Advance Adult Nasal Spray

Store below 25°C in a cool, dry place. Protect from light. Keep container tightly closed; keep out of reach of children.

Expert advice for Otrivin Advance Adult Nasal Spray

Blow your nose gently before using the spray. Steam inhalation and saline rinses help without any rebound risk.

Manufacturer and class

Manufacturer:
GlaxoSmithKline Consumer Pvt Ltd
Therapeutic class:
Nasal decongestant
Drug class:
Topical alpha-adrenergic agonist (imidazoline derivative)

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Otrivin Advance Adult Nasal Spray FAQs

What is Otrivin Advance Adult Nasal Spray used for?
Otrivin Advance Adult Nasal Spray is commonly used for Relief of nasal congestion due to common cold, allergic rhinitis (hay fever), sinusitis; may help open blocked nose and improve breathing. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Otrivin Advance Adult Nasal Spray?
Otrivin Advance Adult Nasal Spray contains Xylometazoline hydrochloride 0.1% w/v (1 mg/mL) nasal spray. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Otrivin Advance Adult Nasal Spray?
For adults and adolescents ≥12 years: 1 spray in each nostril up to 2-3 times daily as needed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Otrivin Advance Adult Nasal Spray work?
Xylometazoline is an alpha-adrenergic agonist that constricts blood vessels in the nasal mucosa.
Is Otrivin Advance Adult Nasal Spray a prescription medicine?
No. Otrivin Advance Adult Nasal Spray is available over the counter (OTC), no prescription is required. However, it is always safer to consult a doctor or pharmacist before use.
What are the common side effects of Otrivin Advance Adult Nasal Spray?
The side effects reported most often with Otrivin Advance Adult Nasal are Nasal dryness, burning or stinging in nose/throat, sneezing, irritation, headache. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Otrivin Advance Adult Nasal Spray be taken during pregnancy?
Consult doctor Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Otrivin Advance Adult Nasal.
Can I drink alcohol while taking Otrivin Advance Adult Nasal Spray?
No known interaction
What if I miss a dose of Otrivin Advance Adult Nasal Spray?
Apply it as soon as you remember.
Is Otrivin Advance Adult Nasal Spray habit forming?
No. Otrivin Advance Adult Nasal Spray is not known to be habit forming when taken as prescribed.
How much does Otrivin Advance Adult Nasal Spray cost on PingMeDoc Pharmacy?
Otrivin Advance Adult Nasal Spray starts at ₹240 on PingMeDoc Pharmacy. Available in spray 10 Gm. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Otrivin Advance Adult Nasal Spray?
Otrivin Advance Adult Nasal Spray is manufactured by GlaxoSmithKline Consumer Pvt Ltd. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Otrivin Advance Adult Nasal Spray delivered?
Otrivin Advance Adult Nasal Spray is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Otrivin Advance Adult Nasal Spray, Quick facts

Salt
Xylometazoline hydrochloride 0.1% w/v (1 mg/mL) nasal spray
Form
spray
Best price
₹240 (₹24.00 per g)
Prescription
Not required (OTC)
Brand
GlaxoSmithKline Consumer Pvt Ltd
Manufacturer
GlaxoSmithKline Consumer Pvt Ltd
Therapeutic class
Nasal decongestant
Drug class
Topical alpha-adrenergic agonist (imidazoline derivative)
Habit forming
No
Variants
spray 10 Gm
Delivery
Standard across India

References

The information on Otrivin Advance Adult Nasal Spray is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack insert, established medical literature (adrenergic agonists), standard pharmacology references
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Otrivin Advance Adult Nasal Spray.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.