Panalto-Dsr Capsule

Composition of Panalto-Dsr Capsule

Panalto-Dsr Capsule contains Pantoprazole (as enteric-coated pellets) 40 mg + Domperidone (as sustained/modified release) 30 mg. It belongs to the Proton pump inhibitor (Pantoprazole) + Dopamine D2 receptor antagonist/prokinetic (Domperidone SR) class of medicines.

Uses of Panalto-Dsr Capsule

• Gastroesophageal reflux disease (GERD)
• acidity/heartburn
• indigestion (dyspepsia)
• nausea and vomiting associated with acid reflux

Key benefits

• Relieves acidity and heartburn
• Helps heal reflux-related irritation
• Reduces regurgitation and bloating
• Controls nausea and vomiting due to reflux

How Panalto-Dsr Capsule works

Pantoprazole is a proton pump inhibitor that reduces stomach acid by blocking the gastric H+/K+ ATPase pump. Domperidone is a peripheral dopamine (D2) receptor antagonist that increases gastric motility and helps relieve nausea/vomiting, improving reflux symptoms.

How to take Panalto-Dsr Capsule

Take 1 capsule as prescribed, usually once daily 30 minutes before food (preferably before breakfast). Swallow whole; do not crush or chew (contains enteric-coated/SR components).

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine may cause confusion, blurred vision, sweating and a fast heartbeat. It can cause drowsiness, disorientation and abnormal muscle movements. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Panalto-Dsr Capsule

Most side effects of Panalto-Dsr are mild and settle as the body adjusts. Reported side effects include:

• Headache
• diarrhea
• abdominal pain
• nausea
• dry mouth
• dizziness
• flatulence
• constipation

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Panalto-Dsr Capsule

Warnings and precautions

Use with caution in liver disease. Domperidone may increase risk of QT prolongation/serious heart rhythm problems—avoid in patients with known QT prolongation, significant cardiac disease, electrolyte disturbances, or when used with QT-prolonging medicines. Seek medical help for black stools, blood in vomit, persistent vomiting, unexplained weight loss, or severe abdominal pain. Long-term PPI use may be associated with low magnesium/vitamin B12, bone fracture risk, and gastrointestinal infections; use the lowest effective dose.

Do not take Panalto-Dsr if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with bleeding, blockage or perforation of the gut, or with certain heart rhythm disorders.

Interactions with other medicines

Ketoconazole/itraconazole/posaconazole/erlotinib (reduced absorption with pantoprazole), warfarin (monitor INR), digoxin (risk of hypomagnesemia-related toxicity), methotrexate high dose (increased levels), clopidogrel (possible reduced activation; consider alternative PPI if needed), strong CYP3A4 inhibitors like clarithromycin/erythromycin/ketoconazole/ritonavir (increase domperidone levels and QT risk), other QT-prolonging drugs (e.g., amiodarone, sotalol, quinolones, macrolides, antipsychotics)

How to store Panalto-Dsr Capsule

Store below 25°C in a dry place, protected from moisture and light. Keep in original blister pack. Keep out of reach of children.

Expert advice for Panalto-Dsr Capsule

Take it before breakfast, not after a meal. Eat smaller meals, avoid late dinners, raise the head of your bed and avoid smoking — these do as much as the tablet for reflux. Take it shortly before meals for bloating and early fullness. Sip fluids frequently in small amounts, and use oral rehydration salts if you have been vomiting.

Manufacturer and class

Manufacturer:

D EARTH PHARMACEUTICALS

Therapeutic class:

Anti-ulcer/Anti-reflux (PPI + Prokinetic/Antiemetic)

Drug class:

Proton pump inhibitor (Pantoprazole) + Dopamine D2 receptor antagonist/prokinetic (Domperidone SR)