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Prescription requiredMacleods Pharmaceuticals Pvt LtdAntibiotic

Polyclav 375 Tablet

Amoxycillin + Clavulanic Acid

₹259MRP ₹272In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

This medicine needs a prescription.

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Polyclav 375 Tablet is used for this medicine is used in the treatment of bacterial infection, throat infection, chest infection, skin infection and urinary infection.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Amoxycillin + Clavulanic Acid
Available variants: tablet 10`S
Best price: ₹259 (₹25.86 per tablet)
MRP: ₹272
Prescription: Required
Manufacturer: MACLEODS PHARMACEUTICALS LTD

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Polyclav 375 Tablet

Polyclav 375 Tablet contains Amoxycillin + Clavulanic Acid. It belongs to the Penicillin class of medicines.

Uses of Polyclav 375 Tablet

  • This medicine is used in the treatment of bacterial infection
  • throat infection
  • chest infection
  • skin infection and urinary infection.

Key benefits

  • Long-established and effective
  • Works against a wide range of common infections

How Polyclav 375 Tablet works

This medicine combines 2 active ingredients: Amoxycillin and Clavulanic Acid. Amoxycillin kills the bacteria causing your infection by breaking down the wall they need to survive. Clavulanic Acid kills the bacteria causing your infection by breaking down the wall they need to survive.

How to take Polyclav 375 Tablet

Swallow the tablet whole with a glass of water. Do not chew, crush or break it unless your doctor has told you to. Take it with or just after food. Taking it at about the same time each day helps you remember. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause vomiting, severe loose motions and, rarely, fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Polyclav 375 Tablet

Most side effects of Polyclav are mild and settle as the body adjusts. Reported side effects include:

  • Loose motions
  • Nausea
  • Rash
  • Vomiting
  • Thrush

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Polyclav 375 Tablet

PregnancyConsult your doctor before using this in pregnancy.
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholAlcohol may worsen the side effects of this medicine. Limit it.
DrivingNot expected to affect your ability to drive.
KidneyConsult your doctor if you have kidney disease.
LiverUse with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function.
Habit formingNo

Warnings and precautions

Finish the whole course even after you feel better. Stopping early lets the strongest bacteria survive, and they are the ones that come back resistant. Stop and seek emergency care for swelling of the face or throat, difficulty breathing, or a widespread rash — a penicillin allergy can be serious. Tell every doctor and pharmacist if you have ever reacted to penicillin. Tell your doctor if loose motions become severe or watery, or continue after the course — this needs attention rather than an anti-diarrhoeal. Antibiotics do not work against colds, flu or most sore throats, which are caused by viruses.

Do not take Polyclav if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a known penicillin allergy.

Interactions with other medicines

May reduce the reliability of the oral contraceptive pill if you have vomiting or loose motions — use additional precautions during the course. Tell your doctor if you take methotrexate or a blood thinner.

How to store Polyclav 375 Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Polyclav 375 Tablet

Space the doses evenly through the day so the level stays steady. Take a probiotic a few hours apart if loose motions trouble you, and drink plenty of fluids. Never use a leftover antibiotic, or someone else's, for a new illness.

Manufacturer and class

Manufacturer:
MACLEODS PHARMACEUTICALS LTD
Therapeutic class:
Antibiotic
Drug class:
Penicillin

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Polyclav 375 Tablet FAQs

What is Polyclav 375 Tablet used for?
Polyclav 375 Tablet is commonly used for This medicine is used in the treatment of bacterial infection, throat infection, chest infection, skin infection and urinary infection. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Polyclav 375 Tablet?
Polyclav 375 Tablet contains Amoxycillin + Clavulanic Acid. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Polyclav 375 Tablet?
Swallow the tablet whole with a glass of water. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Polyclav 375 Tablet work?
This medicine combines 2 active ingredients: Amoxycillin and Clavulanic Acid.
Is Polyclav 375 Tablet a prescription medicine?
Yes. Polyclav 375 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Polyclav 375 Tablet?
The side effects reported most often with Polyclav are Loose motions, Nausea, Rash, Vomiting, Thrush. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Polyclav 375 Tablet be taken during pregnancy?
Consult your doctor before using this in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Polyclav.
Can I drink alcohol while taking Polyclav 375 Tablet?
Alcohol may worsen the side effects of this medicine.
What if I miss a dose of Polyclav 375 Tablet?
Take it as soon as you remember.
Is Polyclav 375 Tablet habit forming?
No. Polyclav 375 Tablet is not known to be habit forming when taken as prescribed.
How much does Polyclav 375 Tablet cost on PingMeDoc Pharmacy?
Polyclav 375 Tablet starts at ₹259 (MRP ₹272) on PingMeDoc Pharmacy. Available in tablet 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Polyclav 375 Tablet?
Polyclav 375 Tablet is manufactured by MACLEODS PHARMACEUTICALS LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Polyclav 375 Tablet delivered?
Polyclav 375 Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Polyclav 375 Tablet, Quick facts

Salt
Amoxycillin + Clavulanic Acid
Form
tablet
Best price
₹259 (₹25.86 per tablet)
MRP
₹272
Prescription
Required (Rx)
Brand
Macleods Pharmaceuticals Pvt Ltd
Manufacturer
MACLEODS PHARMACEUTICALS LTD
Therapeutic class
Antibiotic
Drug class
Penicillin
Habit forming
No
Variants
tablet 10`S
Delivery
Standard across India

References

The information on Polyclav 375 Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Polyclav 375 Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.