Pregain Nt Tab

Composition

Pregabalin + Nortriptyline (strengths vary by brand; commonly Pregabalin 75 mg + Nortriptyline 10 mg)

Uses of Pregain Nt Tab

Neuropathic (nerve) pain such as diabetic neuropathy, post-herpetic neuralgia, sciatica/radiculopathy, neuropathic pain associated with spinal disorders; also used when nerve pain has burning, tingling or shooting character.

• •Reduces burning/tingling nerve pain
• •Improves sleep disturbed by neuropathic pain
• •Provides dual-mechanism pain relief
• •Helps chronic radicular/sciatic pain symptoms

How it works

Pregabalin reduces abnormal nerve signaling by binding to the alpha-2-delta subunit of voltage-gated calcium channels, decreasing release of pain neurotransmitters. Nortriptyline is a tricyclic antidepressant that increases norepinephrine/serotonin in pain pathways and modulates nerve pain. Together they provide enhanced relief in chronic neuropathic pain.

Directions for use

Tablet; take exactly as prescribed, usually once daily at night (may cause drowsiness). Can be taken with or without food; swallow whole with water. Do not stop suddenly—dose should be tapered by a doctor.

Side effects

Common side effects of Pregain Nt Tab may include:

• •Dizziness
• •drowsiness/somnolence
• •dry mouth
• •constipation