Skip to main content
PingMeDoc
Prescription requiredH & H Pharmaceutical Pvt LtdAnti-acne agent and Topical corticosteroid

Propysalic Plus 6% Lotion

Salicylic Acid (6%w/v) + Clobetasol (0.05%w/v)

₹117MRP ₹123In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

This medicine needs a prescription.

You can pay now and add the prescription afterwards. We pack your order only after a pharmacist verifies it.

Upload prescriptionNo prescription? A doctor will call you (free)

A doctor decides whether a prescription can be issued. If it is not issued, the prescription items in your order are cancelled and refunded. You choose this at checkout.

Propysalic Plus 6% Lotion is used for topisal 6% Lotion is used in the treatment of eczema and psoriasis.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Salicylic Acid (6%w/v) + Clobetasol (0.05%w/v)
Available variants: lotion 6%w/v + 0.05%w/v 30ML
Best price: ₹117 (₹3.90 per ml)
MRP: ₹123
Prescription: Required
Manufacturer: H & H PHARMACEUTICAL PVT LTD

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Propysalic Plus 6% Lotion

Propysalic Plus 6% Lotion contains Salicylic Acid (6%w/v) + Clobetasol (0.05%w/v). It belongs to the Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor class of medicines.

Uses of Propysalic Plus 6% Lotion

Topisal 6% Lotion is used in the treatment of eczema and psoriasis.

Key benefits

  • Clears and prevents acne
  • Improves skin texture and marks over time
  • Rapid relief of itching and inflammation
  • Acts where it is applied

How Propysalic Plus 6% Lotion works

Topisal 6% Lotion is a combination of two medicines: Clobetasol and Salicylic Acid, which treats eczema and psoriasis. Clobetasol is a steroid which blocks the production of certain chemical messengers (prostaglandins) that make the skin red, swollen and itchy. Salicylic Acid is a keratolytic medicine which breaks down keratin clumps, removes dead skin cells and softens the skin. It also enhances the absorption of Clobetasol into the skin.

How to take Propysalic Plus 6% Lotion

Clean and dry the affected area, then apply a thin layer and rub it in gently. Wash your hands before and after use, unless your hands are the area being treated. This is for use on the skin only — do not swallow it. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Apply it as soon as you remember. If it is nearly time for the next application, skip the missed one — applying extra does not make up for it.

If you take too much

An overdose of this medicine can cause severe irritation when far too much cream is applied; an oral retinoid taken in excess can cause headache, vomiting and liver injury. It can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Propysalic Plus 6% Lotion

Most side effects of Propysalic Plus 6% are mild and settle as the body adjusts. Reported side effects include:

  • Dryness
  • Peeling
  • Redness
  • Burning or stinging
  • Increased sensitivity to sunlight
  • Thinning of the skin
  • Stretch marks
  • Acne
  • Change in skin colour

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Propysalic Plus 6% Lotion

PregnancyTopisal 6% Lotion may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor.
BreastfeedingTopisal 6% Lotion is probably safe to use during lactation. Limited human data suggests that the drug does not represent a significant risk to the baby.
AlcoholAlcohol may worsen the side effects of this medicine. Limit it.
DrivingNot expected to affect your ability to drive.
KidneyUse with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function.
LiverConsult your doctor if you have liver disease.
Habit formingNo

Warnings and precautions

Acne often looks worse for the first two to four weeks before it improves. This is expected — do not stop. Use sunscreen every day. These medicines make the skin burn much more easily. Oral isotretinoin must never be taken in pregnancy — it causes severe birth defects. Reliable contraception and the pregnancy tests your dermatologist requires are essential before, during and after the course. Start with alternate nights and build up, and do not use more than a pea-sized amount for the whole face. Do not combine several strong acne actives at once without advice — the irritation compounds. Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted.

Do not take Propysalic Plus 6% if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Oral retinoids are absolutely contraindicated in pregnancy and in anyone who might become pregnant without a pregnancy prevention programme. Topical retinoids are avoided in pregnancy. Not for untreated bacterial, fungal or viral skin infections. Not for use in or around the eyes.

Interactions with other medicines

Do not combine with other peeling agents or with waxing and harsh scrubs. Oral retinoids must not be combined with tetracycline antibiotics. No significant interactions are expected from preparations used on the skin.

How to store Propysalic Plus 6% Lotion

Store below 30°C, away from direct sunlight. Close the cap tightly after each use. Keep out of the reach of children.

Expert advice for Propysalic Plus 6% Lotion

Apply retinoids at night to clean, dry skin, and moisturise afterwards. Give it at least eight to twelve weeks before judging whether it works. Do not pick or squeeze spots — that is what leaves scars. Apply a thin layer — a fingertip's worth covers an area about the size of two adult palms. Use a plain moisturiser generously alongside it; that is what keeps eczema away between flares. Ask your doctor for a written plan of how long to use it and when to step down.

Manufacturer and class

Manufacturer:
H & H PHARMACEUTICAL PVT LTD
Therapeutic class:
Anti-acne agent and Topical corticosteroid
Drug class:
Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor

More from H & H Pharmaceutical Pvt Ltd

View categories
Amrfy Cream
5% offRx

Amrfy Cream

H & H Pharmaceutical Pvt Ltd - Cream - 0.25%W/W - 30 G

₹390₹411

Save ₹21

Prescription required

Amrfy Xl Cream
5% offRx

Amrfy Xl Cream

H & H Pharmaceutical Pvt Ltd - Cream - 0.25%W/W - 50 G

₹488₹514

Save ₹26

Prescription required

5% off

Aquahance Adv.Night Rep.Serum

H & H Pharmaceutical Pvt Ltd - 25 ml

₹950₹1,000

Save ₹50

Aquahance Hair Revi.Cond.
5% off

Aquahance Hair Revi.Cond.

H & H Pharmaceutical Pvt Ltd - 150 G

₹998₹1,050

Save ₹52

Aquahance Moist.Surge F/W
5% off

Aquahance Moist.Surge F/W

H & H Pharmaceutical Pvt Ltd - 100 ml

₹356₹375

Save ₹19

Aquahance Moist.Surge Gel
5% off

Aquahance Moist.Surge Gel

H & H Pharmaceutical Pvt Ltd - Gel - 45 G

₹998₹1,050

Save ₹52

5% off

Aquahance Moist.Surge Soap

H & H Pharmaceutical Pvt Ltd - Soap - 125 G

₹285₹300

Save ₹15

Arezy Duo Nasal Spray
5% offRx

Arezy Duo Nasal Spray

H & H Pharmaceutical Pvt Ltd - Spray - 7 G

₹403₹424

Save ₹21

Prescription required

More in Acne Care

View categories
Caricom Tab
5% offRx

Caricom Tab

Comed Chemicals - Tablet - 15 S

₹387₹408

Save ₹21

Prescription required

Com-D3 Strong Cap
5% offRx

Com-D3 Strong Cap

Comed Chemicals - Capsule - 1500mcg + 50mg + 0.25mcg + 7.5mg + 45mcg + 1250mg + 800mcg - 10 S

₹244₹257

Save ₹13

Prescription required

Cortimax Sus
Rx

Cortimax Sus

Zuventus Healthcare Ltd - 30 ml

₹91₹95

Save ₹4

Prescription required

Desowen Lotion
5% offRx

Desowen Lotion

Galderma India Pvt Ltd - Lotion - 0.05%W/W - 30 ml

₹276₹291

Save ₹15

Prescription required

Dobecure Cream
5% offRx

Dobecure Cream

Walfs Pharma - Cream - 5%W/W + 0.25%W/W + 0.25%W/W + 3%W/W - 30 G

₹128₹135

Save ₹7

Prescription required

Dronis-P 4MG Tab
5% offRx

Dronis-P 4MG Tab

Sun Pharma - Tablet - 4 mg - 24 S

₹456₹480

Save ₹24

Prescription required

5% offRx

Eglucent Mix 25 Kwikpen

Lupin Lab - 3 ml

₹1,416₹1,490

Save ₹74

Prescription required

Essendo-E2 Tab
5% offRx

Essendo-E2 Tab

Olympus - Tablet - 2mg - 28 S

₹355₹374

Save ₹19

Prescription required

Popular on PingMeDoc Pharmacy

View categories
Wysolone Dt 5 Tablet
9% offRx

Wysolone Dt 5 Tablet

Pfizer Ltd - Tablet - 15 Tablet

₹10₹11

Save ₹1

Prescription required

D9 Hairblendz Nutritional Hair Kit
5% off

D9 Hairblendz Nutritional Hair Kit

D9 Healthcare Llp - Kit

₹1,581₹1,664

Save ₹83

Vaseline Jelly 12GM

12 G

₹10
15% off

Artery Forceps 6"Cd.Pak

1*1

₹510₹600

Save ₹90

Rbx Aid Plaster

100 S

₹4
7% off

Funplay Condom Choco 3S

Funplay - 1*3*30

₹28₹30

Save ₹2

15% off

Adson Forceps

1

₹298₹350

Save ₹52

Rbx Aid Plaster New

1

₹4₹4

Propysalic Plus 6% Lotion FAQs

What is Propysalic Plus 6% Lotion used for?
Propysalic Plus 6% Lotion is commonly used for Topisal 6% Lotion is used in the treatment of eczema and psoriasis. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Propysalic Plus 6% Lotion?
Propysalic Plus 6% Lotion contains Salicylic Acid (6%w/v) + Clobetasol (0.05%w/v). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Propysalic Plus 6% Lotion?
Clean and dry the affected area, then apply a thin layer and rub it in gently. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Propysalic Plus 6% Lotion work?
Topisal 6% Lotion is a combination of two medicines: Clobetasol and Salicylic Acid, which treats eczema and psoriasis.
Is Propysalic Plus 6% Lotion a prescription medicine?
Yes. Propysalic Plus 6% Lotion is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Propysalic Plus 6% Lotion?
The side effects reported most often with Propysalic Plus 6% are Dryness, Peeling, Redness, Burning or stinging, Increased sensitivity to sunlight. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Propysalic Plus 6% Lotion be taken during pregnancy?
Topisal 6% Lotion may be unsafe to use during pregnancy.<br>Animal studies have shown adverse effects on the foetus, however, there are limited human studies. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Propysalic Plus 6%.
Can I drink alcohol while taking Propysalic Plus 6% Lotion?
Alcohol may worsen the side effects of this medicine.
What if I miss a dose of Propysalic Plus 6% Lotion?
Apply it as soon as you remember.
Is Propysalic Plus 6% Lotion habit forming?
No. Propysalic Plus 6% Lotion is not known to be habit forming when taken as prescribed.
How much does Propysalic Plus 6% Lotion cost on PingMeDoc Pharmacy?
Propysalic Plus 6% Lotion starts at ₹117 (MRP ₹123) on PingMeDoc Pharmacy. Available in lotion 6%w/v + 0.05%w/v 30ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Propysalic Plus 6% Lotion?
Propysalic Plus 6% Lotion is manufactured by H & H PHARMACEUTICAL PVT LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Propysalic Plus 6% Lotion delivered?
Propysalic Plus 6% Lotion is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Propysalic Plus 6% Lotion, Quick facts

Salt
Salicylic Acid (6%w/v) + Clobetasol (0.05%w/v)
Form
lotion
Best price
₹117 (₹3.90 per ml)
MRP
₹123
Prescription
Required (Rx)
Brand
H & H PHARMACEUTICAL PVT LTD
Manufacturer
H & H PHARMACEUTICAL PVT LTD
Therapeutic class
Anti-acne agent and Topical corticosteroid
Drug class
Retinoid / keratolytic and Corticosteroid / calcineurin inhibitor
Habit forming
No
Variants
lotion 6%w/v + 0.05%w/v 30ML
Delivery
Standard across India

References

The information on Propysalic Plus 6% Lotion is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Propysalic Plus 6% Lotion.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.