Prothiaden 25 Tablet

Composition of Prothiaden 25 Tablet

Prothiaden 25 Tablet contains Dosulepin (Dothiepin) Hydrochloride 25 mg. It belongs to the Tricyclic antidepressant (TCA) class of medicines.

Uses of Prothiaden 25 Tablet

Treatment of depression (especially with anxiety); may be used for depressive illness as prescribed by a psychiatrist/physician

Key benefits

• Helps relieve symptoms of depression
• Reduces associated anxiety and tension
• Improves sleep in depressed patients (sedative effect)
• Enhances mood and interest in daily activities

How Prothiaden 25 Tablet works

Dosulepin is a tricyclic antidepressant (TCA). It increases levels of serotonin and noradrenaline in the brain by inhibiting their reuptake, helping improve mood and reduce anxiety symptoms. It also has anticholinergic and sedative effects which may contribute to some side effects.

How to take Prothiaden 25 Tablet

Take by mouth as directed by the doctor, usually once daily at night or in divided doses. Can be taken with or without food; taking at bedtime may reduce daytime drowsiness. Swallow whole with water; do not stop suddenly without medical advice.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Prothiaden 25 Tablet

Most side effects of Prothiaden are mild and settle as the body adjusts. Reported side effects include:

• Drowsiness/sedation
• dry mouth
• constipation
• blurred vision
• dizziness
• weight gain
• nausea
• sweating
• tremor
• palpitations
• postural hypotension

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Prothiaden 25 Tablet

Warnings and precautions

Prescription Schedule H medicine. May cause drowsiness—avoid driving/operating machinery until you know the effect. Risk of suicidal thoughts/behaviour particularly in young adults at start or dose changes—seek urgent help if worsening mood or self-harm thoughts occur. Use with caution in heart disease, arrhythmias, recent myocardial infarction, epilepsy, liver impairment, glaucoma, urinary retention/prostatic hypertrophy, and elderly (falls/confusion). Do not use with MAO inhibitors or within 14 days of stopping them. Taper gradually to avoid withdrawal symptoms.

Do not take Prothiaden if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.

Interactions with other medicines

MAO inhibitors (contraindicated), alcohol and other CNS depressants (increased sedation), other antidepressants/serotonergic drugs (risk of serotonin syndrome), QT-prolonging drugs (arrhythmia risk), antiarrhythmics, anticholinergics, antihypertensives (additive hypotension), cimetidine (may increase levels), enzyme inducers like carbamazepine/phenytoin (may reduce levels), tramadol (seizure/serotonin risk)

How to store Prothiaden 25 Tablet

Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.

Expert advice for Prothiaden 25 Tablet

Give it a fair trial of several weeks, and keep your review appointments. Take it at the same time each day — at night if it makes you drowsy, in the morning if it disturbs sleep. Talking therapy alongside medicine works better than either alone for most people.

Manufacturer and class

Manufacturer:

ABBOTT INDIA LTD

Therapeutic class:

Antidepressant

Drug class:

Tricyclic antidepressant (TCA)