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Prescription requiredAbbott India LimitedAntidepressant
Prothiaden 25 Tablet
Dosulepin (Dothiepin) Hydrochloride 25 mg
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Prothiaden 25 Tablet is used for treatment of depression (especially with anxiety); may be used for depressive illness as prescribed by a psychiatrist/physician.
Licensed pharmacyPharmacist-verified order
Key details
Salt: Dosulepin (Dothiepin) Hydrochloride 25 mg
Available variants: tablet 15 Tablet
Price: ₹202 (₹13.46 per tablet)
Prescription: Required
Manufacturer: ABBOTT INDIA LTD
Ordering notes
Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy
Composition of Prothiaden 25 Tablet
Prothiaden 25 Tablet contains Dosulepin (Dothiepin) Hydrochloride 25 mg. It belongs to the Tricyclic antidepressant (TCA) class of medicines.
Uses of Prothiaden 25 Tablet
- Depression (especially with anxiety)
- May be used for depressive illness as prescribed by a psychiatrist
- Physician
Benefits of Prothiaden 25 Tablet
- In Depression
- Prothiaden restores the balance of the brain's chemical messengers, gradually lifting mood, energy, sleep and appetite. The benefit builds over several weeks, which is why it is important to keep taking it.
- In Anxiety
- Prothiaden calms persistent worry and the physical tension that goes with it, so that everyday situations feel manageable again.
- In Obsessive compulsive disorder
- Prothiaden reduces the intrusive thoughts and the urge to repeat rituals, usually alongside talking therapy.
- In Nerve pain
- Prothiaden dampens the pain signals from damaged nerves, easing burning, shooting or tingling pain that ordinary painkillers do not touch.
- In Migraine prevention
- Prothiaden, taken every day, reduces how often migraines come and how severe they are. It does not treat an attack once it has started.
How Prothiaden 25 Tablet works
Dosulepin is a tricyclic antidepressant (TCA). It increases levels of serotonin and noradrenaline in the brain by inhibiting their reuptake, helping improve mood and reduce anxiety symptoms. It also has anticholinergic and sedative effects which may contribute to some side effects.
How to take Prothiaden 25 Tablet
Take by mouth as directed by the doctor, usually once daily at night or in divided doses. Can be taken with or without food; taking at bedtime may reduce daytime drowsiness. Swallow whole with water; do not stop suddenly without medical advice.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
Missed dose and overdose
If you miss a dose
Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.
If you take too much
An overdose of this medicine can cause fits, dangerous heart rhythm disturbance and coma, and is particularly dangerous with the older tricyclic medicines. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Side effects of Prothiaden 25 Tablet
Most side effects of Prothiaden are mild and settle as the body gets used to the medicine. The ones reported most often are:
- Drowsiness/sedation
- dry mouth
- constipation
- blurred vision
- dizziness
- weight gain
- nausea
- sweating
- tremor
- palpitations
- postural hypotension
Stop the medicine and get help at once for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
Safety advice for Prothiaden 25 Tablet
- AlcoholUNSAFE
- Do not drink alcohol while taking this medicine.
- PregnancyCONSULT YOUR DOCTOR
- Consult your doctor before using this in pregnancy.
- Breast feedingCONSULT YOUR DOCTOR
- Consult your doctor before using this while breastfeeding.
- DrivingCAUTION
- May cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
- KidneyCAUTION
- Use with caution if you have kidney disease. Your doctor may adjust the dose or monitor your kidney function.
- LiverCONSULT YOUR DOCTOR
- Consult your doctor if you have liver disease.
Warnings and precautions
Prescription Schedule H medicine. May cause drowsiness—avoid driving/operating machinery until you know the effect. Risk of suicidal thoughts/behaviour particularly in young adults at start or dose changes—seek urgent help if worsening mood or self-harm thoughts occur. Use with caution in heart disease, arrhythmias, recent myocardial infarction, epilepsy, liver impairment, glaucoma, urinary retention/prostatic hypertrophy, and elderly (falls/confusion). Do not use with MAO inhibitors or within 14 days of stopping them. Taper gradually to avoid withdrawal symptoms.
Do not take Prothiaden if
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Must not be combined with a monoamine oxidase inhibitor, or started within the gap your doctor specifies after one.
Interactions with other medicines
MAO inhibitors (contraindicated), alcohol and other CNS depressants (increased sedation), other antidepressants/serotonergic drugs (risk of serotonin syndrome), QT-prolonging drugs (arrhythmia risk), antiarrhythmics, anticholinergics, antihypertensives (additive hypotension), cimetidine (may increase levels), enzyme inducers like carbamazepine/phenytoin (may reduce levels), tramadol (seizure/serotonin risk)
How to store Prothiaden 25 Tablet
Store below 25°C in a cool, dry place. Protect from light and moisture. Keep out of reach of children.
Quick tips for Prothiaden 25 Tablet
- Give it a fair trial of several weeks, and keep your review appointments.
- Take it at the same time each day.
- At night if it makes you drowsy, in the morning if it disturbs sleep.
- Talking therapy alongside medicine works better than either alone for most people.
Manufacturer and class
- Manufacturer:
- ABBOTT INDIA LTD
- Therapeutic class:
- Antidepressant
- Drug class:
- Tricyclic antidepressant (TCA)
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Prothiaden 25 Tablet FAQs
What is Prothiaden 25 Tablet used for?
Prothiaden 25 Tablet is commonly used for Treatment of depression (especially with anxiety); may be used for depressive illness as prescribed by a psychiatrist/physician. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What are the benefits of Prothiaden 25 Tablet?
Depression: Prothiaden restores the balance of the brain's chemical messengers, gradually lifting mood, energy, sleep and appetite. The benefit builds over several weeks, which is why it is important to keep taking it. It is also used for anxiety, obsessive compulsive disorder, nerve pain.
What is the salt in Prothiaden 25 Tablet?
Prothiaden 25 Tablet contains Dosulepin (Dothiepin) Hydrochloride 25 mg. If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Prothiaden 25 Tablet?
Take by mouth as directed by the doctor, usually once daily at night or in divided doses. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Prothiaden 25 Tablet work?
Dosulepin is a tricyclic antidepressant (TCA).
Is Prothiaden 25 Tablet a prescription medicine?
Yes. Prothiaden 25 Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Prothiaden 25 Tablet?
The side effects reported most often with Prothiaden are Drowsiness/sedation, dry mouth, constipation, blurred vision, dizziness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Prothiaden 25 Tablet be taken during pregnancy?
Consult your doctor before taking Prothiaden 25 Tablet in pregnancy. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Prothiaden.
Can I drink alcohol while taking Prothiaden 25 Tablet?
No. Do not drink alcohol while taking Prothiaden 25 Tablet.
What if I miss a dose of Prothiaden 25 Tablet?
Take it as soon as you remember.
Is Prothiaden 25 Tablet habit forming?
No. Prothiaden 25 Tablet is not known to be habit forming when taken as prescribed.
How much does Prothiaden 25 Tablet cost on PingMeDoc Pharmacy?
Prothiaden 25 Tablet starts at ₹202 on PingMeDoc Pharmacy. Available in tablet 15 Tablet. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Prothiaden 25 Tablet?
Prothiaden 25 Tablet is manufactured by ABBOTT INDIA LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Prothiaden 25 Tablet delivered?
Prothiaden 25 Tablet is delivered across India from our licensed pharmacy. Orders placed before 2 pm ship the same day, later ones the next day, every day of the week. Chennai: next-day delivery by Porter, ₹99 (free above ₹1,499). Enter your pincode on the page to see the date it reaches you.
Prothiaden 25 Tablet, Quick facts
- Salt
- Dosulepin (Dothiepin) Hydrochloride 25 mg
- Form
- tablet
- Price
- ₹202 (₹13.46 per tablet)
- Prescription
- Required (Rx)
- Schedule
- Schedule H
- Brand
- Abbott India Limited
- Manufacturer
- ABBOTT INDIA LTD
- Therapeutic class
- Antidepressant
- Drug class
- Tricyclic antidepressant (TCA)
- Habit forming
- No
- Variants
- tablet 15 Tablet
- Delivery
- Standard across India
References
Compiled from the manufacturer's prescribing information and the sources below, and reviewed by a registered pharmacist. It does not replace your own doctor's advice.
- Manufacturer labeling/pack insert
- CDSCO/Schedule H requirements, established medical literature on tricyclic antidepressants
- Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
- National List of Essential Medicines (NLEM) 2022, Government of India.
- Manufacturer's package insert / prescribing information for Prothiaden 25 Tablet.
- World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.
Next steps
Safety disclaimer
Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.