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Prescription requiredMankind (pharma)GASTRO INTESTINAL

Rifasmart 400 mg Tablet

Rifaximin (400mg)

Rifasmart 400 mg Tablet is used for treatment of Infectious diarrhea.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹355₹35.53 per tablet
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Rifaximin (400mg)
Available variants: tablet 400 mg 10`S
Best price: ₹355 (₹35.53 per tablet)
Prescription: Required
Manufacturer: MANKIND (PHARMA)

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Same salt, lower price

Medicines with the same active ingredient and strength as Rifasmart 400 mg Tablet.

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Rifasmart 400 mg Tablet

tablet - 400 mg - 10 S

₹355

₹35.53 per tablet

Compare all substitutes
Same salt, different brand — what does that mean?

A substitute contains the same active ingredient (salt), in the same strength, as Rifasmart 400 mg Tablet. The medicine inside is the same — the brand name, manufacturer and price are what differ.

All medicines sold in India, branded or generic, must meet the quality standards set by the national drug regulator (CDSCO). A lower price does not mean lower quality.

Please confirm with your doctor or pharmacist before switching brands — they will check that the strength and form match your prescription.

Composition of Rifasmart 400 mg Tablet

Rifasmart 400 mg Tablet contains Rifaximin (400mg). It belongs to the Antibiotic class of medicines.

Uses of Rifasmart 400 mg Tablet

Treatment of Infectious diarrhea

Key benefits

  • In Treatment of Infectious diarrhea Infectious diarrhea is a condition characterized by the sudden onset of loose or watery stools caused by harmful microorganisms in the digestive system. Rifasmart 400 Tablet helps treat infectious diarrhea by targeting and stopping the growth of harmful bacteria in the intestines. This medicine interferes with the bacteria's ability to make important proteins they need to survive and multiply. This helps to get rid of the bad bacteria causing the infection
  • which in turn reduces the diarrhea and helps you feel better.

How Rifasmart 400 mg Tablet works

Rifasmart 400 Tablet is an antibiotic. It works by killing the ammonia-producing bacteria in the digestive tract. This treats your infection and relieves symptoms of hepatic encephalopathy (agitation, confusion, muscle problems). This also helps reduce the recurrence of episodes of hepatic encephalopathy.

How to take Rifasmart 400 mg Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rifasmart 400 Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Rifasmart 400 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause vomiting, severe loose motions and nerve symptoms. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Rifasmart 400 mg Tablet

Most side effects of Rifasmart are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Rifasmart 400 mg Tablet

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol UNSAFE
DrivingDriving CONSULT YOUR DOCTOR
KidneyKidney CONSULT YOUR DOCTOR
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

Use with caution in patients with liver disease, may cause orange discoloration of urine, sweat, and tears. Regular liver function tests are recommended.

Do not take Rifasmart if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack.

Interactions with other medicines

May interact with anticoagulants, oral contraceptives, and certain antiretroviral drugs.

How to store Rifasmart 400 mg Tablet

Store at room temperature (20-25°C), away from light and moisture.

Expert advice for Rifasmart 400 mg Tablet

Rifasmart 400 Tablet reduces the risk of overt hepatic encephalopathy (HE) recurrence in patients with liver disease. It may cause reddish discoloration of urine. This is normal and harmless. Stop taking Rifasmart 400 Tablet and inform your doctor if you have severe diarrhea during or after using Rifasmart 400 Tablet. Finish the full course of the medication, even if you feel better.

Manufacturer and class

Manufacturer:
MANKIND (PHARMA)
Therapeutic class:
GASTRO INTESTINAL
Drug class:
Antibiotic
Chemical class:
Macrolactams

Substitutes for Rifasmart 400 mg Tablet

Medicines with the same active ingredient (Rifaximin (400mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Rifasmart 400 mg Tablet
Riforte 400 TabletSamarth Life Sciences Pvt Ltdtablet · 10`S₹3443% cheaper
Rifaxigress 400 mg TabletLARENONtablet · 10`S₹3521% cheaper
Rifakem 400 mg TabletALKEM LABtablet · 10`S₹38910% more
Rifaximax 400 TabletZuventus Healthcare Ltdtablet · 10`S₹39110% more
Dirifa 400 mg TabletAbbott India Limitedtablet · 10`S₹43221% more
Torfix 400 mg TabletTorrent Pharmaceuticals Ltdtablet · 10`S₹43723% more
Rifagut 400 mg TabletSUN PHARMAtablet · 10`S₹45027% more
Zimigut 400 mg TabletIntas Pharmaceuticals Ltdtablet · 10`S₹48436% more
Rcifax 400 mg TabletLUPIN LABtablet · 10`S₹48436% more
Sibofix 400 mg TabletDr Reddys Laboratories Ltdtablet · 10`S₹48837% more
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Rifasmart 400 mg Tablet FAQs

What is Rifasmart 400 mg Tablet used for?
Rifasmart 400 mg Tablet is commonly used for Treatment of Infectious diarrhea. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Rifasmart 400 mg Tablet?
Rifasmart 400 mg Tablet contains Rifaximin (400mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Rifasmart 400 mg Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Rifasmart 400 mg Tablet work?
Rifasmart 400 Tablet is an antibiotic.
Is Rifasmart 400 mg Tablet a prescription medicine?
Yes. Rifasmart 400 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Rifasmart 400 mg Tablet?
The side effects reported most often with Rifasmart are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Rifasmart 400 mg Tablet be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Rifasmart.
Can I drink alcohol while taking Rifasmart 400 mg Tablet?
Alcohol UNSAFE
What if I miss a dose of Rifasmart 400 mg Tablet?
If you miss a dose of Rifasmart 400 Tablet, take it as soon as possible.
Is Rifasmart 400 mg Tablet habit forming?
No. Rifasmart 400 mg Tablet is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Rifasmart 400 mg Tablet?
Riforte 400 Tablet has the same active ingredient and strength and is listed from ₹344 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Rifasmart 400 mg Tablet cost on PingMeDoc Pharmacy?
Rifasmart 400 mg Tablet starts at ₹355 on PingMeDoc Pharmacy. Available in tablet 400 mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Rifasmart 400 mg Tablet?
Rifasmart 400 mg Tablet is manufactured by MANKIND (PHARMA). PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Rifasmart 400 mg Tablet delivered?
Rifasmart 400 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Rifasmart 400 mg Tablet, Quick facts

Salt
Rifaximin (400mg)
Form
tablet
Best price
₹355 (₹35.53 per tablet)
Prescription
Required (Rx)
Schedule
Schedule H
Brand
MANKIND (PHARMA)
Manufacturer
MANKIND (PHARMA)
Therapeutic class
GASTRO INTESTINAL
Drug class
Antibiotic
Chemical class
Macrolactams
Action class
RNA polymerase inhibitors- Rifamycins
Habit forming
No
Variants
tablet 400 mg 10`S
Delivery
Standard across India

References

The information on Rifasmart 400 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Indian Pharmacopoeia
  2. CDSCO, manufacturer labeling
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Rifasmart 400 mg Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.