Refresh Liquigel
Allergan India Pvt Ltd - 10 ml
₹169₹178
Save ₹9
OTC · No prescriptionPolyethylene Glycol 400 0.4% w/v + Propylene Glycol 0.3% w/v
Systane Ultra, Substitutes & Alternatives
Find medicines with the same composition as Systane Ultra (Polyethylene Glycol 400 0.4% w/v + Propylene Glycol 0.3% w/v (lubricant eye drops)). Compare alternatives at different price points.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Known Substitutes
The following medicines may be used as alternatives to Systane Ultra (same or similar composition):
- Refresh Tears Eye Drops
- Refresh Liquigel Eye Drops
- Tears Naturale II Eye Drops
- Optive Lubricant Eye Drops
- Hylo-Comod Eye Drops
Important: Never switch medicines without consulting your doctor or pharmacist. Even medicines with the same composition may have different inactive ingredients that affect how they work for you.
Understanding the Composition
Systane Ultra contains Polyethylene Glycol 400 0.4% w/v + Propylene Glycol 0.3% w/v (lubricant eye drops). Substitute medicines with the same active ingredient work by the same mechanism and treat the same conditions.
Price differences between brands are common and do not indicate a difference in quality or effectiveness. All medicines sold in India must meet the standards set by CDSCO (Central Drugs Standard Control Organisation).
Available Alternatives on PingMeDoc™
View categories
Refresh Liquigel Eye Drop
Allergan India Pvt Ltd - Drop - 10 ml
₹167₹186
Save ₹19
Refresh Tears
Allergan India Pvt Ltd - 10 ml
₹126₹132
Save ₹6
10% off
Refresh Tears Eye Drops
Allergan India Pvt Ltd - Drop - 10 ml
₹124₹138
Save ₹14
Tears Naturale Forte Drops
Alcon India - Drop - 15 ml
₹418₹440
Save ₹22
Prescription required
Tears Naturale Ii
Alcon India - 5 ml
₹53₹55
Save ₹2
Tears Naturale Ii.
Alcon India - 10 ml
₹175₹184
Save ₹9
Prescription required
Systane Ultra: At a Glance
- Composition
- Polyethylene Glycol 400 0.4% w/v + Propylene Glycol 0.3% w/v (lubricant eye drops)
- Price
- ₹561
- Prescription
- Not required (OTC)
- Manufacturer
- ALCON INDIA
- Known substitutes
- 5
Systane Ultra: Substitute FAQs
Are substitutes as effective as the original medicine?
Substitutes with the same active ingredient (salt) work in a similar way. However, inactive ingredients may differ. Always consult your doctor before switching.
Why are some substitutes cheaper?
Generic medicines are usually cheaper because manufacturers don't have the same development costs as the original brand. They contain the same active ingredient in the same strength.
Can I switch to a substitute on my own?
No. Always consult your doctor or pharmacist before switching medicines, even if the substitute has the same composition.
What is the difference between generic and branded medicines?
Generic medicines contain the same active ingredients as branded ones but are sold under different names, often at lower prices. Both are regulated for safety and efficacy.
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Safety disclaimer
Never switch medicines without consulting your doctor. This page is for educational purposes only. Individual response to medicines may vary.