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OTC · No prescriptionAlcon IndiaOphthalmic lubricant / Artificial tears

Systane Ultra

Polyethylene Glycol 400 0.4% w/v + Propylene Glycol 0.3% w/v (lubricant eye drops)

Systane Ultra is used for relief of dry eye symptoms such as burning, irritation, grittiness, and discomfort due to tear film instability; lubrication for eyes exposed to wind, sun, screen use, air-conditioning or contact lens–related dryness (as advised).

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹561MRP ₹5905% off₹56.05 per ml
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Polyethylene Glycol 400 0.4% w/v + Propylene Glycol 0.3% w/v (lubricant eye drops)
Available variants: NA 10ML
Best price: ₹561 (₹56.05 per ml)
MRP: ₹590
Prescription: Not required
Manufacturer: ALCON INDIA

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Systane Ultra

Systane Ultra contains Polyethylene Glycol 400 0.4% w/v + Propylene Glycol 0.3% w/v (lubricant eye drops). It belongs to the Ocular lubricants (demulcents) class of medicines.

Uses of Systane Ultra

  • Relief of dry eye symptoms such as burning
  • irritation
  • grittiness
  • and discomfort due to tear film instability; lubrication for eyes exposed to wind
  • sun
  • screen use
  • air-conditioning or contact lens–related dryness (as advised).

Key benefits

  • Relieves dryness
  • burning and irritation
  • Stabilizes tear film
  • Provides long-lasting lubrication
  • Soothes gritty/foreign body sensation
  • Helps protect ocular surface from dryness

How Systane Ultra works

Polyethylene glycol 400 and propylene glycol act as ocular lubricants that supplement the tear film and reduce friction on the ocular surface. They help stabilize the tear layer, soothe irritation and provide longer-lasting comfort in dry eye.

How to take Systane Ultra

For ophthalmic use only. Instill 1–2 drops in the affected eye(s) as needed or as directed by a doctor. If using with other eye medicines, keep a gap of at least 5–10 minutes. Do not touch the dropper tip to any surface; recap tightly after use.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause severe loose motions, dehydration and salt imbalance. It is not a realistic risk from a moisturiser used on the skin. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Systane Ultra

Most side effects of Systane Ultra are mild and settle as the body adjusts. Reported side effects include:

  • Temporary blurred vision
  • mild eye irritation or burning
  • eye redness
  • watery eyes
  • sticky sensation
  • foreign body sensation

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Systane Ultra

PregnancyGenerally safe (minimal systemic absorption); consult doctor if pregnant
BreastfeedingConsult your doctor before using this while breastfeeding.
AlcoholNo known interaction
DrivingNot expected to affect your ability to drive.
KidneyUse with caution if you have kidney disease — your doctor may adjust the dose or monitor your kidney function.
LiverUse with caution if you have liver disease — your doctor may adjust the dose or monitor your liver function.
Habit formingNo

Warnings and precautions

For external use in the eyes only. Remove contact lenses before instillation if advised; reinsert after 15 minutes (or as per label/doctor). Stop use and consult a doctor if eye pain, vision changes, persistent redness/irritation, or symptoms worsen or persist. Do not use if seal is broken or solution changes color/turns cloudy. Avoid contamination—do not touch dropper tip. Use caution while driving immediately after use due to temporary blurring.

Do not take Systane Ultra if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for anyone with a suspected bowel obstruction, or with severe abdominal pain of unknown cause.

Interactions with other medicines

No clinically significant drug interactions known with topical ocular lubricants; separate from other eye drops by 5–10 minutes to avoid washout/dilution.

How to store Systane Ultra

Store at room temperature (generally below 25–30°C), protected from light and moisture. Keep the bottle tightly closed. Do not freeze. Discard as per pack instructions after opening.

Expert advice for Systane Ultra

Increase fibre, fluids and physical activity — these treat the cause rather than the episode. Do not ignore the urge to go; a regular routine helps. Use lukewarm water, a soap substitute and short baths. Smooth it on in the direction the hair grows rather than rubbing it in hard. Keep using it when the skin looks normal — that is what prevents the next flare.

Manufacturer and class

Manufacturer:
ALCON INDIA
Therapeutic class:
Ophthalmic lubricant / Artificial tears
Drug class:
Ocular lubricants (demulcents)

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Systane Ultra FAQs

What is Systane Ultra used for?
Systane Ultra is commonly used for Relief of dry eye symptoms such as burning, irritation, grittiness, and discomfort due to tear film instability; lubrication for eyes exposed to wind, sun, screen use, air-conditioning or contact lens–related dryness (as advised). Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Systane Ultra?
Systane Ultra contains Polyethylene Glycol 400 0.4% w/v + Propylene Glycol 0.3% w/v (lubricant eye drops). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Systane Ultra?
For ophthalmic use only. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Systane Ultra work?
Polyethylene glycol 400 and propylene glycol act as ocular lubricants that supplement the tear film and reduce friction on the ocular surface.
Is Systane Ultra a prescription medicine?
No. Systane Ultra is available over the counter (OTC), no prescription is required. However, it is always safer to consult a doctor or pharmacist before use.
What are the common side effects of Systane Ultra?
The side effects reported most often with Systane Ultra are Temporary blurred vision, mild eye irritation or burning, eye redness, watery eyes, sticky sensation. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Systane Ultra be taken during pregnancy?
Generally safe (minimal systemic absorption); consult doctor if pregnant Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Systane Ultra.
Can I drink alcohol while taking Systane Ultra?
No known interaction
What if I miss a dose of Systane Ultra?
Take it as soon as you remember.
Is Systane Ultra habit forming?
No. Systane Ultra is not known to be habit forming when taken as prescribed.
How much does Systane Ultra cost on PingMeDoc Pharmacy?
Systane Ultra starts at ₹561 (MRP ₹590) on PingMeDoc Pharmacy. Available in NA 10ML. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Systane Ultra?
Systane Ultra is manufactured by ALCON INDIA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Systane Ultra delivered?
Systane Ultra is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Systane Ultra, Quick facts

Salt
Polyethylene Glycol 400 0.4% w/v + Propylene Glycol 0.3% w/v (lubricant eye drops)
Best price
₹561 (₹56.05 per ml)
MRP
₹590
Prescription
Not required (OTC)
Brand
ALCON INDIA
Manufacturer
ALCON INDIA
Therapeutic class
Ophthalmic lubricant / Artificial tears
Drug class
Ocular lubricants (demulcents)
Habit forming
No
Variants
NA 10ML
Delivery
Standard across India

References

The information on Systane Ultra is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling/pack insert (Alcon), established medical literature on ocular lubricants, standard ophthalmology references
  2. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  3. National List of Essential Medicines (NLEM) 2022, Government of India.
  4. Manufacturer's package insert / prescribing information for Systane Ultra.
  5. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.