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Prescription requiredPharmed LtdPAIN ANALGESICS

Thrize Plus

Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg)

₹290MRP ₹305In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Thrize Plus is used for pain relief.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg)
Available variants: NA 10`S
Best price: ₹290
MRP: ₹305
Prescription: Required
Manufacturer: PHARMED LIMITED

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Thrize Plus

Thrize Plus contains Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg). It belongs to the Enzyme / disease-modifying anti-rheumatic agent and Non-steroidal anti-inflammatory drug class of medicines.

Uses of Thrize Plus

Pain relief

Key benefits

  • In Pain relief Thrize Plus Tablet relieves pain
  • reduce swelling and ease inflammation in conditions like rheumatoid arthritis
  • osteoarthritis and ankylosing spondolytis. It also gives relief from muscle and back pain
  • toothache
  • or pain in the ear and throat. It works by reducing substances in the body that causes pain and swelling. Take it as prescribed to get the most benefit. This will help you to go about your daily activities more easily and have a better
  • more active
  • quality of life.

How Thrize Plus works

Thrize Plus Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside and Diclofenac. Trypsin and Bromelain are enzymes. They increase blood supply and make the body produce substances that fight pain and swelling. Rutoside is an antioxidant which protects the body from damage by chemicals (free radicals) and further reduces swelling. Diclofenac is a non-steroidal antiinflammatory drug (NSAID) which works by blocking the release of certain chemical messengers (prostaglandins) in the brain that cause pain and inflammation (redness and swelling).

How to take Thrize Plus

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Thrize Plus Tablet is to be taken on an empty stomach.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Thrize Plus Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can seriously suppress the bone marrow and damage the liver. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Thrize Plus

Most side effects of Thrize Plus are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Thrize Plus

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding UNSAFE
AlcoholAlcohol CONSULT YOUR DOCTOR
DrivingDriving CAUTION
KidneyKidney UNSAFE
LiverLiver UNSAFE
Habit formingNo

Warnings and precautions

Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.

Do not take Thrize Plus if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.

Interactions with other medicines

Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.

How to store Thrize Plus

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Thrize Plus

Thrize Plus Tablet helps relieve pain and inflammation that may occur due to trauma, surgery or everyday activity. It may also be used to relieve inflammation in rheumatic and degenerative conditions, such as rheumatoid arthritis and osteoarthritis. Take it with plenty of fluids, an hour before or two hours after a meal. It may increase the severity of your condition at the start of treatment. Continue using it as prescribed by your doctor. It may cause dizziness and blurred vision. Do not drive or do anything requiring concentration until you know how it affects you. It may change the color, consistency, and odor of your stool. This is harmless. Inform your doctor if this bothers you.

Manufacturer and class

Manufacturer:
PHARMED LIMITED
Therapeutic class:
PAIN ANALGESICS
Drug class:
Enzyme / disease-modifying anti-rheumatic agent and Non-steroidal anti-inflammatory drug

Substitutes for Thrize Plus

Medicines with the same active ingredient (Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg)). Ask your doctor or pharmacist before switching brands.

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Isibro D TabletEYSYS PHARMAtablet · 10`S₹22024% cheaper
Zymoflam D TabletARISTO PHARMACEUTICALS PVT LTDtablet · 10`S₹3097% more
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Thrize Plus FAQs

What is Thrize Plus used for?
Thrize Plus is commonly used for Pain relief. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Thrize Plus?
Thrize Plus contains Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Thrize Plus?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Thrize Plus work?
Thrize Plus Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside and Diclofenac.
Is Thrize Plus a prescription medicine?
Yes. Thrize Plus is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Thrize Plus?
The side effects reported most often with Thrize Plus are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Thrize Plus be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Thrize Plus.
Can I drink alcohol while taking Thrize Plus?
Alcohol CONSULT YOUR DOCTOR
What if I miss a dose of Thrize Plus?
If you miss a dose of Thrize Plus Tablet, take it as soon as possible.
Is Thrize Plus habit forming?
No. Thrize Plus is not known to be habit forming when taken as prescribed.
Is there a cheaper substitute for Thrize Plus?
Isibro D Tablet has the same active ingredient and strength and is listed from ₹220 on PingMeDoc Pharmacy. Ask your doctor or pharmacist before switching brands, the salt is the same, but excipients and release profiles can differ.
How much does Thrize Plus cost on PingMeDoc Pharmacy?
Thrize Plus starts at ₹290 (MRP ₹305) on PingMeDoc Pharmacy. Available in NA 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Thrize Plus?
Thrize Plus is manufactured by PHARMED LIMITED. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Thrize Plus delivered?
Thrize Plus is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Thrize Plus, Quick facts

Salt
Trypsin (48mg) + Bromelain (90mg) + Rutoside (100mg) + Diclofenac (50mg)
Best price
₹290
MRP
₹305
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Pharmed Ltd
Manufacturer
PHARMED LIMITED
Therapeutic class
PAIN ANALGESICS
Drug class
Enzyme / disease-modifying anti-rheumatic agent and Non-steroidal anti-inflammatory drug
Habit forming
No
Variants
NA 10`S
Delivery
Standard across India

References

The information on Thrize Plus is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Thrize Plus.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.