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Prescription requiredEysys PharmaAnalgesic and anti-inflammatory

Isibro D Tablet

Diclofenac (50mg) + Bromelain (90mg) + Trypsin (48mg) + Rutoside (100mg)

₹220MRP ₹232In stock

Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.

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Isibro D Tablet is used for isibro-D Tablet is used for pain relief.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Diclofenac (50mg) + Bromelain (90mg) + Trypsin (48mg) + Rutoside (100mg)
Available variants: tablet 50mg + 90mg + 48mg + 100mg 10`S
Best price: ₹220 (₹22.02 per tablet)
MRP: ₹232
Prescription: Required
Manufacturer: EYSYS PHARMA

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Isibro D Tablet

Isibro D Tablet contains Diclofenac (50mg) + Bromelain (90mg) + Trypsin (48mg) + Rutoside (100mg). It belongs to the Non-steroidal anti-inflammatory drug and Enzyme / disease-modifying anti-rheumatic agent class of medicines.

Uses of Isibro D Tablet

Isibro-D Tablet is used for pain relief.

Key benefits

  • Relieves pain and the swelling that causes it
  • Effective in arthritis and injury
  • Reduces swelling and joint damage over time
  • Improves function in inflammatory disease

How Isibro D Tablet works

Isibro-D Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside and Diclofenac. Trypsin and Bromelain are enzymes. They increase blood supply and make the body produce substances that fight pain and swelling. Rutoside is an antioxidant which protects the body from damage by chemicals (free radicals) and further reduces swelling. Diclofenac is a non-steroidal antiinflammatory drug (NSAID) which works by blocking the release of certain chemical messengers (prostaglandins) in the brain that cause pain and inflammation (redness and swelling).

How to take Isibro D Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Isibro-D Tablet is to be taken with food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine can cause stomach bleeding, kidney failure, drowsiness and fits. It can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Isibro D Tablet

Most side effects of Isibro D are mild and settle as the body adjusts. Reported side effects include:

  • Indigestion
  • Stomach pain
  • Nausea
  • Heartburn
  • Dizziness
  • Swelling of the ankles and feet
  • Stomach upset
  • Loose motions
  • Rash
  • Raised liver enzymes

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Isibro D Tablet

PregnancyIsibro-D Tablet is unsafe to use during pregnancy.<br>There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening situations. Please consult your doctor.
BreastfeedingNo information is available on the use of Isibro-D Tablet during lactation. Please consult your doctor.
AlcoholIt is not known whether it is safe to consume alcohol with Isibro-D Tablet . Please consult your doctor.
DrivingMay cause drowsiness or affect your concentration. Do not drive until you know how it affects you.
KidneyIsibro-D Tablet is probably safe to use in patients with kidney disease. Limited data available suggests that dose adjustment of Isibro-D Tablet may not be needed in these patients. Please consult your doctor.
LiverIsibro-D Tablet is probably safe to use in patients with liver disease. Limited data available suggests that dose adjustment of Isibro-D Tablet may not be needed in these patients. Please consult your doctor.
Habit formingNo

Warnings and precautions

Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack.

Do not take Isibro D if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.

How to store Isibro D Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Isibro D Tablet

<div class="style__desktop-container___1hcBT"><div class="style__desktop-video___2GTR9"><div class="styles__video-img___1rCzR"><div class=""/><div class=""/></div></div><div><div><div><div><div class="ExpertAdviceItem__content___1Djk2"><ul><li>Isibro-D Tablet helps relieve pain and inflammation that may occur due to trauma, surgery or everyday activity.</li> <li>It may also be used to relieve inflammation in rheumatic and degenerative conditions, such as rheumatoid arthritis and osteoarthritis.</li> <li>Take it with plenty of fluids, an hour before or two hours after a meal.</li> <li>It may increase the severity of your condition at the start of treatment. Continue using it as prescribed by your doctor.</li> <li>It may cause dizziness and blurred vision. Do not drive or do anything requiring concentration until you know how it affects you.</li> <li>It may change the color, consistency, and odor of your stool. This is harmless. Inform your doctor if this bothers you.</li></ul></div></div></div></div></div></div>

Manufacturer and class

Manufacturer:
EYSYS PHARMA
Therapeutic class:
Analgesic and anti-inflammatory
Drug class:
Non-steroidal anti-inflammatory drug and Enzyme / disease-modifying anti-rheumatic agent

Substitutes for Isibro D Tablet

Medicines with the same active ingredient (Diclofenac (50mg) + Bromelain (90mg) + Trypsin (48mg) + Rutoside (100mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Isibro D Tablet
Thrize PlusPharmed Ltd10`S₹29032% more
Zymoflam D TabletARISTO PHARMACEUTICALS PVT LTDtablet · 10`S₹30940% more
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Isibro D Tablet FAQs

What is Isibro D Tablet used for?
Isibro D Tablet is commonly used for Isibro-D Tablet is used for pain relief. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Isibro D Tablet?
Isibro D Tablet contains Diclofenac (50mg) + Bromelain (90mg) + Trypsin (48mg) + Rutoside (100mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Isibro D Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Isibro D Tablet work?
Isibro-D Tablet is a combination of four medicines: Trypsin, Bromelain, Rutoside and Diclofenac.
Is Isibro D Tablet a prescription medicine?
Yes. Isibro D Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Isibro D Tablet?
The side effects reported most often with Isibro D are Indigestion, Stomach pain, Nausea, Heartburn, Dizziness. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Isibro D Tablet be taken during pregnancy?
Isibro-D Tablet is unsafe to use during pregnancy.<br>There is positive evidence of human fetal risk, but the benefits from use in pregnant women may be acceptable despite the risk, for example in life-threatening... Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Isibro D.
Can I drink alcohol while taking Isibro D Tablet?
It is not known whether it is safe to consume alcohol with Isibro-D Tablet .
What if I miss a dose of Isibro D Tablet?
Take it as soon as you remember.
Is Isibro D Tablet habit forming?
No. Isibro D Tablet is not known to be habit forming when taken as prescribed.
How much does Isibro D Tablet cost on PingMeDoc Pharmacy?
Isibro D Tablet starts at ₹220 (MRP ₹232) on PingMeDoc Pharmacy. Available in tablet 50mg + 90mg + 48mg + 100mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Isibro D Tablet?
Isibro D Tablet is manufactured by EYSYS PHARMA. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Isibro D Tablet delivered?
Isibro D Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Isibro D Tablet, Quick facts

Salt
Diclofenac (50mg) + Bromelain (90mg) + Trypsin (48mg) + Rutoside (100mg)
Form
tablet
Best price
₹220 (₹22.02 per tablet)
MRP
₹232
Prescription
Required (Rx)
Schedule
Schedule H
Brand
EYSYS PHARMA
Manufacturer
EYSYS PHARMA
Therapeutic class
Analgesic and anti-inflammatory
Drug class
Non-steroidal anti-inflammatory drug and Enzyme / disease-modifying anti-rheumatic agent
Habit forming
No
Variants
tablet 50mg + 90mg + 48mg + 100mg 10`S
Delivery
Standard across India

References

The information on Isibro D Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Isibro D Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.