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Prescription requiredLupin LabSkeletal muscle relaxant

Tolifast SR 450 mg Tablet

Tolperisone (450mg)

Tolifast SR 450 mg Tablet is used for relief of painful muscle spasm and increased muscle tone in acute musculoskeletal conditions (e.g., back/neck pain, sprains/strains), adjunct in spasticity management as advised by physician.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

₹337₹56.16 per tablet
Licensed pharmacyPharmacist-verified orderDelivered across India

Key details

Salt: Tolperisone (450mg)
Available variants: tablet 450 mg 6`S
Best price: ₹337 (₹56.16 per tablet)
Prescription: Required
Manufacturer: LUPIN LAB

Ordering notes

Standard delivery across India. No same-day delivery nationally.
Chennai express delivery is possible and chargeable. Learn more
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Tolifast SR 450 mg Tablet

Tolifast SR 450 mg Tablet contains Tolperisone (450mg). It belongs to the Centrally acting muscle relaxant (tolperisone) class of medicines.

Uses of Tolifast SR 450 mg Tablet

  • Relief of painful muscle spasm and increased muscle tone in acute musculoskeletal conditions (e.g.
  • back/neck pain
  • sprains/strains)
  • adjunct in spasticity management as advised by physician.

Key benefits

  • Relieves painful muscle spasm
  • Reduces muscle stiffness
  • Improves mobility in acute back/neck pain
  • Helps functional recovery with physiotherapy
  • Sustained-release for prolonged effect

How Tolifast SR 450 mg Tablet works

Tolperisone is a centrally acting muscle relaxant that reduces reflex muscle spasm. It stabilizes nerve membranes and inhibits abnormal nerve signal transmission in spinal pathways, leading to muscle relaxation and pain relief without significant sedation in many patients.

How to take Tolifast SR 450 mg Tablet

Tablet (SR) to be taken exactly as prescribed. Swallow whole with water; do not crush or chew. Usually taken after food to reduce stomach upset; take at the same time each day.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Tolifast SR Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause deep drowsiness, muscle weakness, a fall in blood pressure and slowed breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Tolifast SR 450 mg Tablet

Most side effects of Tolifast SR are mild and settle as the body adjusts. Reported side effects include:

  • dizziness
  • headache
  • nausea
  • vomiting
  • abdominal discomfort
  • diarrhea
  • weakness
  • drowsiness
  • low blood pressure
  • skin rash

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Tolifast SR 450 mg Tablet

PregnancyConsult doctor (use only if clearly needed)
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholUse with caution (may increase dizziness/drowsiness)
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

Use with caution in liver or kidney impairment; dose adjustment/monitoring may be needed. May cause dizziness or drowsiness—avoid driving/operating machinery if affected. Stop and seek medical help if allergic reactions occur (rash, swelling, breathing difficulty). Not recommended for children unless prescribed. Inform doctor if you have myasthenia gravis or severe hypotension.

Do not take Tolifast SR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with myasthenia gravis or severe liver disease.

Interactions with other medicines

Alcohol and other CNS depressants (increased dizziness/drowsiness), antihypertensives (additive low blood pressure), sedatives/anxiolytics, opioids, muscle relaxants, NSAIDs (generally compatible but follow doctor advice).

How to store Tolifast SR 450 mg Tablet

Store below 25°C in a dry place, protected from light and moisture. Keep out of reach of children.

Expert advice for Tolifast SR 450 mg Tablet

Tolifast SR Tablet provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system. Consider taking with or after food or a glass of milk to prevent upset stomach. Tolifast SR Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.

Manufacturer and class

Manufacturer:
LUPIN LAB
Therapeutic class:
Skeletal muscle relaxant
Drug class:
Centrally acting muscle relaxant (tolperisone)
Chemical class:
Aminoketones

Substitutes for Tolifast SR 450 mg Tablet

Medicines with the same active ingredient (Tolperisone (450mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Tolifast SR 450 mg Tablet
Synaptol SR 450SUN PHARMA10`S₹39216% more
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Tolifast SR 450 mg Tablet FAQs

What is Tolifast SR 450 mg Tablet used for?
Tolifast SR 450 mg Tablet is commonly used for Relief of painful muscle spasm and increased muscle tone in acute musculoskeletal conditions (e.g., back/neck pain, sprains/strains), adjunct in spasticity management as advised by physician. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Tolifast SR 450 mg Tablet?
Tolifast SR 450 mg Tablet contains Tolperisone (450mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Tolifast SR 450 mg Tablet?
Tablet (SR) to be taken exactly as prescribed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Tolifast SR 450 mg Tablet work?
Tolperisone is a centrally acting muscle relaxant that reduces reflex muscle spasm.
Is Tolifast SR 450 mg Tablet a prescription medicine?
Yes. Tolifast SR 450 mg Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Tolifast SR 450 mg Tablet?
The side effects reported most often with Tolifast SR are dizziness, headache, nausea, vomiting, abdominal discomfort. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Tolifast SR 450 mg Tablet be taken during pregnancy?
Consult doctor (use only if clearly needed) Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Tolifast SR.
Can I drink alcohol while taking Tolifast SR 450 mg Tablet?
Use with caution (may increase dizziness/drowsiness)
What if I miss a dose of Tolifast SR 450 mg Tablet?
If you miss a dose of Tolifast SR Tablet, take it as soon as possible.
Is Tolifast SR 450 mg Tablet habit forming?
No. Tolifast SR 450 mg Tablet is not known to be habit forming when taken as prescribed.
How much does Tolifast SR 450 mg Tablet cost on PingMeDoc Pharmacy?
Tolifast SR 450 mg Tablet starts at ₹337 on PingMeDoc Pharmacy. Available in tablet 450 mg 6`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Tolifast SR 450 mg Tablet?
Tolifast SR 450 mg Tablet is manufactured by LUPIN LAB. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Tolifast SR 450 mg Tablet delivered?
Tolifast SR 450 mg Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Tolifast SR 450 mg Tablet, Quick facts

Salt
Tolperisone (450mg)
Form
tablet
Best price
₹337 (₹56.16 per tablet)
Prescription
Required (Rx)
Brand
LUPIN LAB
Manufacturer
LUPIN LAB
Therapeutic class
Skeletal muscle relaxant
Drug class
Centrally acting muscle relaxant (tolperisone)
Chemical class
Aminoketones
Action class
Centrally Acting Skeletal Muscle Relaxants
Habit forming
No
Variants
tablet 450 mg 6`S
Delivery
Standard across India

References

The information on Tolifast SR 450 mg Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. Manufacturer labeling, established medical literature on tolperisone
  2. Indian drug references/compendia, pharmacology texts
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Tolifast SR 450 mg Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.