
A B Phylline Caps
Sun Pharma - Capsule - 15 S
Save ₹15
Prescription required
Tolperisone (450mg)
Delivery across India. Free above ₹999; ₹49 from ₹499, ₹99 below. Chennai express delivery is chargeable.
This medicine needs a prescription.
You can pay now and add the prescription afterwards. We pack your order only after a pharmacist verifies it.
A doctor decides whether a prescription can be issued. If it is not issued, the prescription items in your order are cancelled and refunded. You choose this at checkout.
Synaptol SR 450 is used for muscle relaxation.
Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026
Synaptol SR 450 contains Tolperisone (450mg). It belongs to the Centrally acting muscle relaxant class of medicines.
Muscle relaxation
SynAPTOL SR 450 Tablet is a muscle relaxant. It works on the centres in the brain and spinal cord to relieve muscle stiffness or spasm without reduction in strength. This improves pain and movement of muscles.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. SynAPTOL SR 450 Tablet should be taken with or after food.
Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.
If you miss a dose of SynAPTOL SR 450 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
An overdose of this medicine can cause deep drowsiness, muscle weakness, a fall in blood pressure and slowed breathing. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.
Most side effects of Synaptol SR are mild and settle as the body adjusts. Reported side effects include:
Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.
| Pregnancy | Pregnancy CONSULT YOUR DOCTOR |
|---|---|
| Breastfeeding | Breast feeding CONSULT YOUR DOCTOR |
| Alcohol | Alcohol SAFE |
| Driving | Driving UNSAFE |
| Kidney | Kidney CAUTION |
| Liver | Liver CAUTION |
| Habit forming | No |
This medicine causes drowsiness. Do not drive or operate machinery until you know how it affects you. Use it for the short course your doctor has prescribed — these are not intended for long-term use. Do not stop a long course abruptly without asking your doctor.
Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with myasthenia gravis or severe liver disease.
Alcohol, sleeping tablets, antihistamines and opioid painkillers all add to the drowsiness, sometimes dangerously.
Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.
SynAPTOL SR 450 Tablet provides relief from rigidity, tension and stiffness in muscles (spasticity) that may occur due to various conditions affecting the nervous system. Consider taking with or after food or a glass of milk to prevent upset stomach. SynAPTOL SR 450 Tablet may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. Do not stop taking it suddenly without talking to your doctor if you've been on it for a long time.
Medicines with the same active ingredient (Tolperisone (450mg)). Ask your doctor or pharmacist before switching brands.
| Medicine | Pack | Price | vs Synaptol SR 450 |
|---|---|---|---|
| Tolifast SR 450 mg TabletLUPIN LAB | tablet · 6`S | ₹352 | 14% cheaper |

Sun Pharma - Capsule - 15 S
Save ₹15
Prescription required
Sun Pharma - Tablet - 10 S
Save ₹13
Prescription required
Sun Pharma - Tablet - 200 mg - 10 S
Save ₹16
Prescription required
Sun Pharma - Syrup - 100 ml
Save ₹9
Prescription required
Sun Pharma - Tablet - 6 Tablet
Save ₹12
Prescription required

Sun Pharma - Tablet - 100mg - 10 S
Save ₹25
Prescription required

Sun Pharma - Tablet - 100mg + 200IU + 200mg - 10 S
Save ₹4

Sun Pharma - 10 S
Save ₹5
Prescription required
Icon Pharma - 10 mg - 10 S
Save ₹6
Prescription required

Icon Pharma - 25 mg - 10 S
Save ₹16
Prescription required

Intas Pharmaceuticals Ltd - Tablet - 10 mg - 15 S
Save ₹10
Prescription required

Larenon - Tablet - 10 mg - 10 S
Save ₹6
Prescription required

Larenon - Tablet - 20 mg - 10 S
Save ₹9
Prescription required

Propel Health Care - Tablet - 10mg - 10 S
Save ₹6
Prescription required
1 X6
Save ₹4
Prescription required
1 X10
Save ₹2
Prescription required

Pfizer Ltd - Tablet - 15 Tablet
Save ₹1
Prescription required

D9 Healthcare Llp - Kit
Save ₹83
12 G
1*1
Save ₹90
100 S
Funplay - 1*3*30
Save ₹2
1
Save ₹52
1
The information on Synaptol SR 450 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.