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Prescription requiredIntas Pharmaceuticals LtdPAIN ANALGESICS

Tolperitas D SR Tablet

Tolperisone (450mg) + Diclofenac (100mg)

Currently out of stock

Same composition, in stock now. Check with your doctor or pharmacist before you switch.

  • Myotop Dsr Tablet₹262View

Tolperitas D SR Tablet is used for pain due to muscle spasm.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Tolperisone (450mg) + Diclofenac (100mg)
Available variants: tablet 450mg + 100mg 5`S
Best price: ₹135 (₹26.98 per tablet)
MRP: ₹142
Prescription: Required
Manufacturer: INTAS PHARMACEUTICALS`

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Tolperitas D SR Tablet

Tolperitas D SR Tablet contains Tolperisone (450mg) + Diclofenac (100mg). It belongs to the Centrally acting muscle relaxant and Non-steroidal anti-inflammatory drug class of medicines.

Uses of Tolperitas D SR Tablet

Pain due to muscle spasm

Key benefits

  • In Pain due to muscle spasm Tolperitas D 450mg/100mg Tablet SR treats pain due to muscle spasm by relaxing stiff muscles. It also reduces swelling in the muscles. Altogether
  • it helps in easy movement and reduces discomfort. Once you see some improvement
  • you can start doing therapy exercises (such as walking or breathing exercises) that will help you get your strength back more quickly.

How Tolperitas D SR Tablet works

Tolperitas D 450mg/100mg Tablet SR is a combination of two medicines: Tolperisone and Diclofenac, which relieves pain and relaxes the muscles.

How to take Tolperitas D SR Tablet

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Tolperitas D 450mg/100mg Tablet SR should be taken with or after food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Tolperitas D 450mg/100mg Tablet SR, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can cause deep drowsiness, muscle weakness, a fall in blood pressure and slowed breathing. It can cause stomach bleeding, kidney failure, drowsiness and fits. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Tolperitas D SR Tablet

Most side effects of Tolperitas D SR are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Tolperitas D SR Tablet

PregnancyPregnancy UNSAFE
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol SAFE
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingNo

Warnings and precautions

This medicine causes drowsiness. Do not drive or operate machinery until you know how it affects you. Use it for the short course your doctor has prescribed — these are not intended for long-term use. Do not stop a long course abruptly without asking your doctor. Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy.

Do not take Tolperitas D SR if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with myasthenia gravis or severe liver disease. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy.

Interactions with other medicines

Alcohol, sleeping tablets, antihistamines and opioid painkillers all add to the drowsiness, sometimes dangerously. Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time.

How to store Tolperitas D SR Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Tolperitas D SR Tablet

Tolperitas D 450mg/100mg Tablet SR helps relieve pain and muscle spasm that may occur due to strains, sprains, and muscle injuries. It is usually used along with rest and physical therapy. Take it with food to avoid an upset stomach. It may cause dizziness. Do not drive or do anything requiring concentration until you know how it affects you. Avoid consuming alcohol when taking Tolperitas D 450mg/100mg Tablet SR as it may cause excessive drowsiness.

Manufacturer and class

Manufacturer:
INTAS PHARMACEUTICALS`
Therapeutic class:
PAIN ANALGESICS
Drug class:
Centrally acting muscle relaxant and Non-steroidal anti-inflammatory drug

Substitutes for Tolperitas D SR Tablet

Medicines with the same active ingredient (Tolperisone (450mg) + Diclofenac (100mg)). Ask your doctor or pharmacist before switching brands.

MedicinePackPricevs Tolperitas D SR Tablet
Myotop Dsr TabletZuventus Healthcare Ltdtablet · 5`S₹26294% more
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Tolperitas D SR Tablet FAQs

What is Tolperitas D SR Tablet used for?
Tolperitas D SR Tablet is commonly used for Pain due to muscle spasm. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Tolperitas D SR Tablet?
Tolperitas D SR Tablet contains Tolperisone (450mg) + Diclofenac (100mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Tolperitas D SR Tablet?
Take this medicine in the dose and duration as advised by your doctor. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Tolperitas D SR Tablet work?
Tolperitas D 450mg/100mg Tablet SR is a combination of two medicines: Tolperisone and Diclofenac, which relieves pain and relaxes the muscles.
Is Tolperitas D SR Tablet a prescription medicine?
Yes. Tolperitas D SR Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Tolperitas D SR Tablet?
The side effects reported most often with Tolperitas D SR are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Tolperitas D SR Tablet be taken during pregnancy?
Pregnancy UNSAFE Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Tolperitas D SR.
Can I drink alcohol while taking Tolperitas D SR Tablet?
Alcohol SAFE
What if I miss a dose of Tolperitas D SR Tablet?
If you miss a dose of Tolperitas D 450mg/100mg Tablet SR, take it as soon as possible.
Is Tolperitas D SR Tablet habit forming?
No. Tolperitas D SR Tablet is not known to be habit forming when taken as prescribed.
How much does Tolperitas D SR Tablet cost on PingMeDoc Pharmacy?
Tolperitas D SR Tablet starts at ₹135 (MRP ₹142) on PingMeDoc Pharmacy. Available in tablet 450mg + 100mg 5`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Tolperitas D SR Tablet?
Tolperitas D SR Tablet is manufactured by INTAS PHARMACEUTICALS`. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Tolperitas D SR Tablet delivered?
Tolperitas D SR Tablet is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Tolperitas D SR Tablet, Quick facts

Salt
Tolperisone (450mg) + Diclofenac (100mg)
Form
tablet
Best price
₹135 (₹26.98 per tablet)
MRP
₹142
Prescription
Required (Rx)
Schedule
Schedule H
Brand
Intas Pharmaceuticals Ltd
Manufacturer
INTAS PHARMACEUTICALS`
Therapeutic class
PAIN ANALGESICS
Drug class
Centrally acting muscle relaxant and Non-steroidal anti-inflammatory drug
Habit forming
No
Variants
tablet 450mg + 100mg 5`S
Delivery
Standard across India

References

The information on Tolperitas D SR Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Tolperitas D SR Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.