Topimac 40

Composition of Topimac 40

Topimac 40 contains Topiroxostat (40mg). It belongs to the Enzyme / disease-modifying anti-rheumatic agent class of medicines.

Uses of Topimac 40

Gout

Key benefits

• In Gout Topimac 40 Tablet is used to prevent and treat gout. Gout is caused by too much uric acid in your body. When the level becomes too high
• crystals may form in and around certain joints and your kidneys. This can cause sudden and severe pain
• redness
• warmth
• and swelling. This medicine works by reducing the levels of uric acid in your blood. This makes it less likely that you will suffer the symptoms and make them milder if you do have them. It is usually for long-term treatment and should be taken regularly until the dose is completed.

How Topimac 40 works

Gout occurs due to increased blood uric acid levels. Topimac 40 Tablet reduces the synthesis of uric acid by inhibiting the enzyme involved in it.

How to take Topimac 40

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Topimac 40 Tablet may be taken with or without food.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Topimac 40 Tablet, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.

If you take too much

An overdose of this medicine can seriously suppress the bone marrow and damage the liver. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Topimac 40

Most side effects of Topimac are mild and settle as the body adjusts. Reported side effects include:

• Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Topimac 40

Warnings and precautions

Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack.

Do not take Topimac if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.

How to store Topimac 40

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Topimac 40

Take adequate water or fluids while taking Topimac 40 Tablet to prevent kidney stones. Treatment with this medicine should not be started during a sudden/severe gout attack. Wait until your current attack is over before starting this medication. Consult your doctor before taking it if you have or ever had kidney stones, stomach ulcers, peptic ulcers, diabetes, liver disorders or blood disorders. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding. Take adequate water or fluids while taking Topimac 40 Tablet to prevent kidney stones. Treatment with this medicine should not be started during a sudden/severe gout attack. Wait until your current attack is over before starting this medication. Consult your doctor before taking it if you have or ever had kidney stones, stomach ulcers, peptic ulcers, diabetes, liver disorders or blood disorders. Tell your doctor if you are pregnant, plan to become pregnant, or are breastfeeding.

Manufacturer and class

Manufacturer:

MACLEODS PHARMACEUTICALS LTD

Therapeutic class:

PAIN ANALGESICS

Drug class:

Enzyme / disease-modifying anti-rheumatic agent

Chemical class:

Pyridyl- 1,2,4- triazoles