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Prescription requiredFiziks Life ScienceTopical antifungal, Topical antibiotic and Topical corticosteroid

Upketo K5

Tolnaftate (1%w/w) + Iodochlorhydroxyquinoline (1%w/w) + Clobetasol (0.05%w/w) + Neomycin (0.1%w/w) + Ketoconazole (2%w/w)

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Upketo K5 is used for this medicine is used in the treatment of fungal skin infection, ringworm, athlete's foot, dandruff, nail fungal infection, skin infection, infected wounds, impetigo, boils, eczema, dermatitis, psoriasis and skin inflammation and itching.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Tolnaftate (1%w/w) + Iodochlorhydroxyquinoline (1%w/w) + Clobetasol (0.05%w/w) + Neomycin (0.1%w/w) + Ketoconazole (2%w/w)
Available variants: NA 15GM
Best price: ₹76 (₹5.05 per g)
MRP: ₹80
Prescription: Required
Manufacturer: FIZIKS LIFE SCIENCE

Ordering notes

Delivery details are shown when the medicine is back in stock.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Upketo K5

Upketo K5 contains Tolnaftate (1%w/w) + Iodochlorhydroxyquinoline (1%w/w) + Clobetasol (0.05%w/w) + Neomycin (0.1%w/w) + Ketoconazole (2%w/w). It belongs to the Antifungal, Topical antibacterial and Corticosteroid / calcineurin inhibitor class of medicines.

Uses of Upketo K5

  • This medicine is used in the treatment of fungal skin infection
  • ringworm
  • athlete's foot
  • dandruff
  • nail fungal infection
  • skin infection
  • infected wounds
  • impetigo
  • boils
  • eczema
  • dermatitis
  • psoriasis and skin inflammation and itching.

Key benefits

  • Acts directly on the infected skin
  • Little absorption into the body
  • Treats a localised infection without whole-body antibiotics
  • Rapid relief of itching and inflammation
  • Acts where it is applied

How Upketo K5 works

Upketo-K5 Cream is a combination of five medicines : Ketoconazole, Clioquinol (Iodochlorhydroxyquin), Tolnaftate, Neomycin, and Clobetasol. Ketoconazole and tolnaftate is an antifungal medication. It kills and stops the growth of the fungi by destroying its cell membrane, thereby treating your skin infection. Clioquinol belongs to a category of drugs called hydroxyquinoline antifungal agents. It acts by interacting with Dna synthesis thus killing the fungi that are responsible for causing the infection. Neomycin is an antibiotic. It stops bacterial growth by preventing synthesis of essential proteins required by bacteria to carry out vital functions. Clobetasol is a steroid. It works by blocking the production of certain chemical messengers that make the skin red, swollen and itchy.

How to take Upketo K5

Use this medicine as your doctor has directed. Follow the dose and the duration written on your prescription.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

Take it as soon as you remember. If your next dose is almost due, skip the one you missed — never take two doses together to catch up.

If you take too much

An overdose of this medicine is unlikely from skin use; swallowing the preparation may cause stomach upset. It is unlikely from skin use. It can suppress the body's own steroid production when it is used for a long time over large areas, especially in children. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Upketo K5

Most side effects of Upketo K5 are mild and settle as the body adjusts. Reported side effects include:

  • Burning or stinging
  • Redness
  • Itching
  • Dryness
  • Peeling
  • Thinning of the skin
  • Stretch marks
  • Acne
  • Change in skin colour

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Upketo K5

PregnancyInformation regarding the use of Upketo-K5 Cream during pregnancy is not available. Please consult your doctor.
BreastfeedingInformation regarding the use of Upketo-K5 Cream during breastfeeding is not available. Please consult your doctor.
AlcoholNo significant interaction with alcohol is expected.
DrivingNot expected to affect your ability to drive.
KidneyNo dose change is usually needed in kidney disease.
LiverNo dose change is usually needed in liver disease.
Habit formingNo

Warnings and precautions

Keep applying for the full period your doctor stated, usually two to four weeks, and for a week or two after the rash has cleared. Stopping when it looks better is why ringworm keeps coming back. Apply a little beyond the visible edge of the patch — the fungus extends further than the redness. Do not use a combination cream containing a steroid on a fungal infection unless a doctor has specifically prescribed it. The steroid calms the redness while the fungus spreads underneath. See a doctor if the rash covers a large area, involves the scalp or nails, or has not improved in two weeks — these usually need tablets as well. Use it for the short course prescribed, usually about a week. Prolonged use of a topical antibiotic breeds resistant bacteria. See a doctor if the area becomes more red, swollen, painful or spreads, or if you develop a fever — a spreading skin infection needs tablets. Clean the area gently before each application. Do not use it on large raw areas or burns unless your doctor has said to. Use it only on the area and for the number of days your doctor specified. Potent steroid creams thin the skin permanently when used for too long. Never use a potent steroid cream on the face, the groin or the underarms unless your doctor has specifically told you to — the skin there is thin and absorbs much more. Do not use it on an infection. A steroid on ringworm, impetigo or herpes makes the infection worse while hiding it. Do not use leftover cream on a new rash, and never pass it to someone else. Stop and see your doctor if the area becomes more painful, weepy or crusted.

Do not take Upketo K5 if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. For external use only. Not for use in the eyes. Not for use in or around the eyes. Not for untreated bacterial, fungal or viral skin infections.

Interactions with other medicines

No significant interactions are expected from preparations used on the skin.

How to store Upketo K5

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Upketo K5

Keep the area clean and completely dry — fungus thrives in moisture and sweat. Wear loose cotton clothing, change it daily, and wash clothes and towels in hot water. Do not share towels, and treat affected family members at the same time. Wash your hands before and after applying, and cover the area if advised. Do not share towels or bedding while an infection is active. Apply a thin layer — a fingertip's worth covers an area about the size of two adult palms. Use a plain moisturiser generously alongside it; that is what keeps eczema away between flares. Ask your doctor for a written plan of how long to use it and when to step down.

Manufacturer and class

Manufacturer:
FIZIKS LIFE SCIENCE
Therapeutic class:
Topical antifungal, Topical antibiotic and Topical corticosteroid
Drug class:
Antifungal, Topical antibacterial and Corticosteroid / calcineurin inhibitor

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Upketo K5 FAQs

What is Upketo K5 used for?
Upketo K5 is commonly used for This medicine is used in the treatment of fungal skin infection, ringworm, athlete's foot, dandruff, nail fungal infection, skin infection, infected wounds, impetigo, boils, eczema, dermatitis, psoriasis and skin inflammation and itching. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Upketo K5?
Upketo K5 contains Tolnaftate (1%w/w) + Iodochlorhydroxyquinoline (1%w/w) + Clobetasol (0.05%w/w) + Neomycin (0.1%w/w) + Ketoconazole (2%w/w). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How should I take Upketo K5?
Use this medicine as your doctor has directed. Take it exactly as prescribed; do not change the dose or stop early without talking to your doctor.
How does Upketo K5 work?
Upketo-K5 Cream is a combination of five medicines : Ketoconazole, Clioquinol (Iodochlorhydroxyquin), Tolnaftate, Neomycin, and Clobetasol.
Is Upketo K5 a prescription medicine?
Yes. Upketo K5 is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Upketo K5?
The side effects reported most often with Upketo K5 are Burning or stinging, Redness, Itching, Dryness, Peeling. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Upketo K5 be taken during pregnancy?
Information regarding the use of Upketo-K5 Cream during pregnancy is not available. Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Upketo K5.
Can I drink alcohol while taking Upketo K5?
No significant interaction with alcohol is expected.
What if I miss a dose of Upketo K5?
Take it as soon as you remember.
Is Upketo K5 habit forming?
No. Upketo K5 is not known to be habit forming when taken as prescribed.
How much does Upketo K5 cost on PingMeDoc Pharmacy?
Upketo K5 starts at ₹76 (MRP ₹80) on PingMeDoc Pharmacy. Available in NA 15GM. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Upketo K5?
Upketo K5 is manufactured by FIZIKS LIFE SCIENCE. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Upketo K5 delivered?
Upketo K5 is delivered across India via our licensed pharmacy partners. Standard delivery timelines are confirmed at checkout. Chennai customers can opt for chargeable same-city express delivery.

Upketo K5, Quick facts

Salt
Tolnaftate (1%w/w) + Iodochlorhydroxyquinoline (1%w/w) + Clobetasol (0.05%w/w) + Neomycin (0.1%w/w) + Ketoconazole (2%w/w)
Best price
₹76 (₹5.05 per g)
MRP
₹80
Prescription
Required (Rx)
Brand
FIZIKS LIFE SCIENCE
Manufacturer
FIZIKS LIFE SCIENCE
Therapeutic class
Topical antifungal, Topical antibiotic and Topical corticosteroid
Drug class
Antifungal, Topical antibacterial and Corticosteroid / calcineurin inhibitor
Habit forming
No
Variants
NA 15GM
Delivery
Standard across India

References

The information on Upketo K5 is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Upketo K5.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.