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Prescription requiredSundyota Numandis Pharmaceuticals Pvt LtdPAIN ANALGESICS

Xytram S Tablet

Tramadol (37.5mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)

Available at our pharmacy counter

This medicine is dispensed in person against a valid prescription and is not sold online. Ask our pharmacist about availability, or speak to a registered doctor.

In-store reference price ₹125

Xytram S Tablet is used for pain relief.

Medically reviewed by Dr. Balaji Krishnan, MBBS · Updated September 2026

Licensed pharmacyPharmacist-verified order

Key details

Salt: Tramadol (37.5mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)
Available variants: tablet 37.5mg + 325mg + 15mg 10`S
Best price: ₹125 (₹12.47 per tablet)
MRP: ₹131
Prescription: Required
Manufacturer: SUNDYOTA NUMANDIS PHARMACEUTICALS PVT LTD

Ordering notes

This medicine is dispensed in person at a licensed pharmacy counter and is not delivered.
Returns & refunds: orders can be cancelled before dispatch; after dispatch, returns depend on the item category. Read the full policy

Composition of Xytram S Tablet

Xytram S Tablet contains Tramadol (37.5mg) + Paracetamol (325mg) + Serratiopeptidase (15mg). It belongs to the Opioid analgesic, Para-aminophenol derivative and Enzyme / disease-modifying anti-rheumatic agent class of medicines.

Uses of Xytram S Tablet

Pain relief

Key benefits

  • In Pain relief Xytram-S Tablet is a pain relieving medicine. It helps reduce pain and swelling in conditions like back ache
  • joint pain
  • muscle pain
  • menstrual pain and toothache. Along with painkillers
  • this medicine also contains an active ingredient called Serratiopeptidase
  • which is an enzyme that promotes the overall healing process and speeds up recovery. Xytram-S Tablet might also reduce fever associated with muscle pain.

How Xytram S Tablet works

Xytram-S Tablet is a combination of three medicines: Tramadol, Paracetamol and Serratiopeptidase. Tramadol is an opoid analgesic (pain reliever) which works by blocking transmission of pain signals to the brain to lower pain perception. Paracetamol is an analgesic and anti-pyretic (fever reducer) which works by blocking the release of certain chemical messengers that cause pain and fever. Serratiopeptidase is an enzyme which works by breaking down abnormal proteins at the site of inflammation, and promotes healing.

How to take Xytram S Tablet

Take exactly as prescribed by your doctor.

Side effects of Xytram S Tablet

Most side effects of Xytram S are mild and settle as the body adjusts. Reported side effects include:

  • Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Xytram S Tablet

PregnancyPregnancy CONSULT YOUR DOCTOR
BreastfeedingBreast feeding CONSULT YOUR DOCTOR
AlcoholAlcohol UNSAFE
DrivingDriving UNSAFE
KidneyKidney CAUTION
LiverLiver CAUTION
Habit formingYes

Warnings and precautions

Take it with or just after food, and for the shortest time that works. Stop and seek urgent care for black or tarry stools, vomiting blood, or severe stomach pain — this group can cause bleeding from the stomach. Long or high-dose use raises the risk of heart attack, stroke and kidney injury, particularly in older people and those already at risk. Avoid if you are dehydrated or have an illness with vomiting or loose motions — the kidneys are vulnerable then. Must be avoided in the last three months of pregnancy. This is an opioid painkiller. It can cause dependence, and should be taken only for the period your doctor has specified. Never combine it with alcohol, sleeping tablets or other sedatives — together they can dangerously slow your breathing. Do not stop a long course abruptly; your doctor will reduce it gradually. Tell your doctor if you have epilepsy or take an antidepressant — tramadol can lower the seizure threshold and can raise serotonin dangerously in combination. Never exceed the daily maximum printed on the pack. Paracetamol overdose damages the liver, and the damage can be silent for a day or two before it becomes serious. Check every other medicine you are taking. Paracetamol is in a very large number of cold, flu and pain combinations, and the doses add together. If you drink alcohol regularly, or have liver disease, ask your doctor what daily limit is safe for you. See a doctor if fever lasts more than three days, or pain more than five. Medicines that suppress the immune system need regular blood tests — do not miss them. Report fever, sore throat, mouth ulcers or unusual bruising promptly if you are on an immune-suppressing medicine. Tell your doctor about any infection, and before any vaccination. Methotrexate for arthritis is taken ONCE A WEEK. Taking it daily by mistake is dangerous — check the day on your pack.

Do not take Xytram S if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with an active stomach ulcer, severe kidney or heart failure, or asthma triggered by aspirin or anti-inflammatory painkillers. Not in the third trimester of pregnancy. Not for people with severe liver disease, except under medical supervision. Not for people with an active serious infection, or with severe liver or bone-marrow disease. Several of these medicines must not be used in pregnancy.

Interactions with other medicines

Combining with a blood thinner or aspirin sharply raises the bleeding risk. Reduces the effect of blood pressure medicines and water tablets, and together with them can harm the kidneys. Never take two anti-inflammatory painkillers at the same time. Regular alcohol use increases the risk of liver injury. Tell your doctor if you are on warfarin — regular high-dose paracetamol can affect it. Tell your doctor about all other medicines, especially anti-inflammatory painkillers and antibiotics. Live vaccines are generally avoided while on immune-suppressing treatment.

How to store Xytram S Tablet

Store below 30°C in the original pack, away from direct sunlight and moisture. Keep out of the reach of children.

Expert advice for Xytram S Tablet

Xytram-S Tablet is used to treat various painful conditions. It is better to take it with milk or food to prevent stomach upset. Drink plenty of water while taking this medicine. Do not take any other pain medicine without asking your doctor first. During long-term treatment, your doctor may want to take regular blood tests to monitor your liver function. Inform your doctor if you have a history of stomach ulcers, heart diseases, high blood pressure, and liver or kidney disease.

Manufacturer and class

Manufacturer:
SUNDYOTA NUMANDIS PHARMACEUTICALS PVT LTD
Therapeutic class:
PAIN ANALGESICS
Drug class:
Opioid analgesic, Para-aminophenol derivative and Enzyme / disease-modifying anti-rheumatic agent

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Xytram S Tablet FAQs

What is Xytram S Tablet used for?
Xytram S Tablet is commonly used for Pain relief. Always follow your doctor's advice, this information is for educational purposes and not a substitute for professional medical guidance.
What is the salt in Xytram S Tablet?
Xytram S Tablet contains Tramadol (37.5mg) + Paracetamol (325mg) + Serratiopeptidase (15mg). If you are allergic to any of these active ingredients or excipients, do not take this medicine and speak to your doctor first.
How does Xytram S Tablet work?
Xytram-S Tablet is a combination of three medicines: Tramadol, Paracetamol and Serratiopeptidase.
Is Xytram S Tablet a prescription medicine?
Yes. Xytram S Tablet is a prescription-only (Rx) medicine. Upload a valid prescription from a registered medical practitioner during checkout. We cannot dispense it without a valid Rx.
What are the common side effects of Xytram S Tablet?
The side effects reported most often with Xytram S are Most side effects do not require any medical attention and disappear as your body adjusts to the medicine. Consult your doctor if they persist or if you’re worried about them. Most are mild and settle as the body adjusts; tell your doctor if any of them persist or worry you, and stop the medicine and seek help at once for a rash, swelling of the face or lips, or difficulty breathing.
Can Xytram S Tablet be taken during pregnancy?
Pregnancy CONSULT YOUR DOCTOR Always tell your doctor if you are pregnant, planning a pregnancy or breastfeeding before starting Xytram S.
Can I drink alcohol while taking Xytram S Tablet?
Alcohol UNSAFE
Is Xytram S Tablet habit forming?
Yes Take Xytram S only as directed and for the duration your doctor advises.
How much does Xytram S Tablet cost on PingMeDoc Pharmacy?
Xytram S Tablet starts at ₹125 (MRP ₹131) on PingMeDoc Pharmacy. Available in tablet 37.5mg + 325mg + 15mg 10`S. Final price is confirmed at checkout and may vary by variant and location.
Who manufactures Xytram S Tablet?
Xytram S Tablet is manufactured by SUNDYOTA NUMANDIS PHARMACEUTICALS PVT LTD. PingMeDoc Pharmacy sources medicines only from licensed manufacturers and distributors.
How is Xytram S Tablet delivered?
Xytram S Tablet is a regulated medicine and is not delivered. It is dispensed in person at a licensed pharmacy counter against a valid prescription. Ask our pharmacist on WhatsApp about availability.

Xytram S Tablet, Quick facts

Salt
Tramadol (37.5mg) + Paracetamol (325mg) + Serratiopeptidase (15mg)
Form
tablet
Best price
₹125 (₹12.47 per tablet)
MRP
₹131
Prescription
Required (Rx)
Schedule
Schedule H1
Brand
SUNDYOTA NUMANDIS PHARMACEUTICALS PVT LTD
Manufacturer
SUNDYOTA NUMANDIS PHARMACEUTICALS PVT LTD
Therapeutic class
PAIN ANALGESICS
Drug class
Opioid analgesic, Para-aminophenol derivative and Enzyme / disease-modifying anti-rheumatic agent
Habit forming
Yes
Variants
tablet 37.5mg + 325mg + 15mg 10`S
Delivery
Standard across India

References

The information on Xytram S Tablet is compiled from the manufacturer's prescribing information and the sources below, and is reviewed by a registered medical practitioner. It does not replace advice from your own doctor.

  1. PingMeDoc clinical monograph library — compiled from Indian package inserts, the Indian Pharmacopoeia
  2. CDSCO schedules and standard pharmacology references. Reviewed for patient readability. This is general information, not a substitute for your doctor's advice.
  3. Central Drugs Standard Control Organisation (CDSCO), Ministry of Health & Family Welfare, Government of India, approved drug and schedule listings.
  4. National List of Essential Medicines (NLEM) 2022, Government of India.
  5. Manufacturer's package insert / prescribing information for Xytram S Tablet.
  6. World Health Organization, ATC/DDD classification and Model Formulary for the active ingredient.

Next steps

Safety disclaimer

Product information is for general awareness and does not replace professional medical advice. Always follow a clinician's guidance and upload a valid prescription when required.