Zeepam Injection

Composition of Zeepam Injection

Zeepam Injection contains Lorazepam (2mg). It belongs to the Benzodiazepine (GABA-A receptor positive allosteric modulator) class of medicines.

Uses of Zeepam Injection

• Short-term management of severe anxiety and agitation
• acute seizures/status epilepticus
• premedication and procedural sedation
• muscle spasm/spasticity (e.g.
• tetanus)
• alcohol withdrawal symptoms (including delirium tremens)

Key benefits

• Rapid control of acute seizures
• Short-term relief of severe anxiety/agitation
• Sedation for procedures/premedication
• Relief of acute muscle spasm/spasticity
• Helps manage alcohol withdrawal symptoms

How Zeepam Injection works

Diazepam is a benzodiazepine that enhances the effect of GABA (an inhibitory neurotransmitter) by binding to GABA-A receptors. This increases chloride influx into neurons, producing anxiolytic, sedative, anticonvulsant and muscle-relaxant effects.

How to take Zeepam Injection

Injection for use only under medical supervision. Given as slow IV injection/IV infusion or deep IM injection as prescribed; dose and rate depend on indication, age and clinical response. Avoid rapid IV administration; monitor breathing, blood pressure and level of sedation.

Take it exactly as your doctor prescribed. Do not change the dose or stop early on your own.

Missed dose and overdose

If you miss a dose

If you miss a dose of Zeepam 2mg Injection, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.\n

If you take too much

An overdose of this medicine can cause deep unconsciousness and dangerously slow breathing, particularly with alcohol or an opioid. Do not wait for symptoms to appear — go to the nearest emergency department and take the pack or strip with you.

Side effects of Zeepam Injection

Most side effects of Zeepam are mild and settle as the body adjusts. Reported side effects include:

• Drowsiness
• dizziness
• sedation
• muscle weakness
• confusion
• ataxia
• injection site pain/irritation
• low blood pressure
• respiratory depression

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zeepam Injection

Warnings and precautions

Schedule X medicine: use strictly on prescription and under supervision. Risk of respiratory depression, excessive sedation and hypotension—higher in elderly, debilitated patients, and with other CNS depressants. Use with caution in liver disease, COPD/sleep apnoea, myasthenia gravis, depression/suicidality. May cause dependence, tolerance and withdrawal; avoid abrupt discontinuation after repeated doses. Do not drive/operate machinery after receiving. IV use requires resuscitation facilities.

Do not take Zeepam if

Not for anyone with a known allergy to this medicine or to any ingredient in the pack. Not for people with severe breathing problems, sleep apnoea, or severe liver disease. Not for anyone with a history of dependence, except under specialist supervision.

Interactions with other medicines

Alcohol and other CNS depressants (opioids, barbiturates, sedating antihistamines, antipsychotics) increase sedation/respiratory depression; opioids carry high risk of profound sedation/coma. CYP inhibitors (cimetidine, omeprazole, fluoxetine, fluvoxamine, azole antifungals, macrolides) may increase diazepam levels. CYP inducers (rifampicin, carbamazepine, phenytoin, phenobarbital) may reduce effect. Valproate may increase sedation. Theophylline/caffeine may reduce sedative effect.

How to store Zeepam Injection

Store below 25°C, protected from light. Do not freeze. Keep in original pack until use; discard if solution is discoloured or contains particles.

Expert advice for Zeepam Injection

The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid consuming alcohol as it may increase dizziness and drowsiness. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion. The addiction / habit-forming potential of this medicine is very high. Take it only as per the dose and duration advised by your doctor It may cause dizziness. Do not drive or do anything that requires mental focus until you know how this medicine affects you. Avoid consuming alcohol as it may increase dizziness and drowsiness. Inform your doctor if you are pregnant, planning to conceive or breastfeeding. Do not stop taking medication suddenly without talking to your doctor as that may lead to nausea, anxiety, agitation, flu-like symptoms, sweating, tremor, and confusion.

Manufacturer and class

Manufacturer:

Tamman Titoe Pharma Pvt Ltd

Therapeutic class:

Anxiolytic / Sedative / Anticonvulsant

Drug class:

Benzodiazepine (GABA-A receptor positive allosteric modulator)

Chemical class:

1,4- benzodiazepines