Zifi-O Dry Syrup

Composition of Zifi-O Dry Syrup

Zifi-O Dry Syrup contains Cefixime 50 mg/5 ml + Ofloxacin 50 mg/5 ml (dry syrup; after reconstitution). It belongs to the Third-generation cephalosporin + Fluoroquinolone combination class of medicines.

Uses of Zifi-O Dry Syrup

• Treatment of susceptible bacterial infections such as acute bacterial diarrhea/dysentery
• enteric fever (typhoid) (as per physician)
• urinary tract infections
• and respiratory tract infections where combination therapy is considered appropriate.

Key benefits

• Helps treat bacterial diarrhea/dysentery
• Broad-spectrum coverage against susceptible bacteria
• Useful in mixed bacterial infections when prescribed
• Reduces fever and infection-related symptoms by eradicating bacteria

How Zifi-O Dry Syrup works

Cefixime is a third-generation cephalosporin antibiotic that inhibits bacterial cell wall synthesis leading to bacterial death. Ofloxacin is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase/topoisomerase IV, preventing DNA replication. Together they provide broad antibacterial coverage against susceptible organisms.

How to take Zifi-O Dry Syrup

Take exactly as prescribed by your doctor.

Side effects of Zifi-O Dry Syrup

Most side effects of Zifi-O Dry are mild and settle as the body adjusts. Reported side effects include:

• Nausea
• vomiting
• diarrhea
• abdominal pain
• indigestion
• headache
• dizziness
• rash
• altered taste

Stop the medicine and seek help immediately for a rash, swelling of the face or lips, wheezing or difficulty breathing. Tell your doctor about any side effect that persists or worries you.

Safety advice for Zifi-O Dry Syrup

Warnings and precautions

Prescription-only antibiotic; use only for bacterial infections and complete the course. Use with caution in kidney disease (dose adjustment may be needed), history of allergy to cephalosporins/penicillins, seizure disorders, and in patients with history of tendon disorders. Fluoroquinolones may rarely cause tendonitis/tendon rupture, peripheral neuropathy, CNS effects and QT prolongation; seek medical help if tendon pain, numbness/tingling, palpitations or severe dizziness occur. Stop and consult doctor if severe diarrhea occurs (risk of C. difficile). Avoid unnecessary use in children unless specifically prescribed; ofloxacin use in children is generally restricted due to effects on growing cartilage—use only when benefits outweigh risks as decided by physician.

Interactions with other medicines

Antacids or supplements containing magnesium/aluminium/calcium/iron/zinc (reduce ofloxacin absorption; separate by 2–4 hours), warfarin/anticoagulants (may increase bleeding risk), NSAIDs (may increase CNS stimulation/seizure risk with quinolones), other QT-prolonging drugs (increased arrhythmia risk), probenecid (may increase cephalosporin levels)

How to store Zifi-O Dry Syrup

Store dry powder below 25°C in a dry place away from light. After reconstitution, store as per label (often in refrigerator or at room temperature as directed) and use within the recommended period (commonly 7–14 days); do not freeze. Keep the bottle tightly closed and out of reach of children.

Manufacturer and class

Manufacturer:

FDC LIMITED

Therapeutic class:

Antibiotic

Drug class:

Third-generation cephalosporin + Fluoroquinolone combination